BIOGALENYS

BIOANALYSIS and BIOPHARMACY - pKa, LogP, LogD, Physiological solubility and stability - in-vitro, in-vivo and ex-vivo assay studies. - Permeability, Absorption, Distribution. - BCS determination. - Franz Cells , Ussing chambers (Skin, Buccal and Nasal mucosa, intestinal segments, corneal and scleral permeability). - Eye distribution and Pharmacokinetic. - In-vitro / in-vivo correlation. ANALYTICAL SERVICES - HPLC-MS-MS ,DAD, UV. - GCMS-EI. - Spectrometry (fluorescence and luminescence), Elisa. COSMETIC SERVICES - Chromatographic qualification and quantification of preservatives (ISO 9001, ISO 22716). - UV filters and vitamin (ISO 9001, ISO 22716). - Actives ingredients analysis. - In-vitro testing : Cutaneous absorption in Franz cells according to guideline OCDE 428. Skin and ocular irritation test. Phototoxicity test. Microbial adhesion on human skin and mucosal segments.