CytoDyn is in late-stage clinical development of leronlimab, a CCR5 receptor antagonist, to be used as a platform drug for various therapeutic indications, including NASH, NASH/HIV, oncology, and HIV. The CCR5 receptor is a protein located on the surface of various cells including white blood cells, stellate cells which produce scar tissue in the liver, cells that undergo malignant transformation, and is the predominant co-receptor needed for certain strains of HIV to infect healthy T-cells. The CCR5 receptor serves as a receptor for chemical attractants called chemokines. Chemokines are the key orchestrators of leukocyte trafficking by attracting immune cells to the sites of inflammation.
Leronlimab is a humanized monoclonal antibody that is a once-a-week subcutaneous injection that can also be administered intravenously. Leronlimab is a competitive rather than allosteric inhibitor of the CCR5 receptor. This mechanism of action of binding competitively to the CCR5 receptor differentiates leronlimab from all other CCR5 antagonists.
Company Details
- Employees
- 23
- Address
- Vancouver, Washington 98660, Us
- Phone
- (360) 980-8524
- in****@****dyn.com
- Industry
- Biotechnology Research
- NAICS
-
Research and Development in Biotechnology (except Nanobiotechnology)
- Website
- cytodyn.com
- Keywords
- Cancer, HIV/AIDS, NASH, Biotechnology, Pharmaceuticals.
- HQ
- VANCOUVER, Washington
Cytodyn Questions
Cytodyn's helpline number is (360) 980-8524
Cytodyn's website is cytodyn.com
Cytodyn's LinkedIn profile is https://www.linkedin.com/company/cytodyn-inc
Cytodyn has
23 employees.
View email and phone details for 23
employees at Cytodyn.
Cytodyn's industry is
Biotechnology Research
Cytodyn's top competitors are
Mosaic Biosciences,
Ksq Therapeutics, Inc.,
Virocell Biologics,
Amarex Clinical Research, Llc, An Nsf Company,
Opthea,
Anixa Biosciences, Inc.,
Diakonos Oncology,
Judo Bio,
Immunome, Inc.,
Bora Pharmaceuticals.
Cytodyn's support email address is info@cytodyn.com
Cytodyn's categories are Biotechnology Research
