Gyre Therapeutics

Gyre Therapeutics company information, Employees & Contact Information

Gyre Therapeutics, Inc. (“Gyre”) (Nasdaq: GYRE) is a commercial-stage biotechnology company developing anti-fibrotic therapeutics for a variety of chronic organ diseases. Gyre is headquartered in San Diego, CA, with a primary focus on the development and commercialization of anti-fibrotic therapeutics for a variety of chronic organ diseases. Gyre has successfully advanced ETUARY® from research to commercialization. Its sales are re-invested to fund Gyre’s clinical development pipeline. Gyre's lead compound F351 is a derivative of ETUARY® (Pirfenidone) and has obtained breakthrough therapy designation status for chronic HBV-associated liver fibrosis. A phase 3 confirmative clinical study is being conducted based on the phase 2 POC clinical data. A F351 phase I study has been completed in the US. An IND for a phase 2 clinical study will be filed for the treatment of NASH-associated fibrosis in the U.S. in 2024. F351 effectively suppresses chronic inflammation pathways, including the TGFbeta signaling pathway. As a result, it presents a promising therapeutic strategy as a single agent and opportunity for combination therapy with metabolic inhibitors in treating organ fibrotic diseases. Gyre is also advancing a diverse pipeline through its indirect controlling interest in Gyre Pharmaceuticals, including ETUARY therapeutic expansions, F573, F528, and F230.

Company Details

Employees
13
Address
12770 High Bluff Drive,
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
HQ
San Diego , CA
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