Gyre Therapeutics, Inc. (“Gyre”) (Nasdaq: GYRE) is a commercial-stage biotechnology company developing anti-fibrotic therapeutics for a variety of chronic organ diseases.
Gyre is headquartered in San Diego, CA, with a primary focus on the development and commercialization of anti-fibrotic therapeutics for a variety of chronic organ diseases. Gyre has successfully advanced ETUARY® from research to commercialization. Its sales are re-invested to fund Gyre’s clinical development pipeline. Gyre's lead compound F351 is a derivative of ETUARY® (Pirfenidone) and has obtained breakthrough therapy designation status for chronic HBV-associated liver fibrosis. A phase 3 confirmative clinical study is being conducted based on the phase 2 POC clinical data. A F351 phase I study has been completed in the US. An IND for a phase 2 clinical study will be filed for the treatment of NASH-associated fibrosis in the U.S. in 2024.
F351 effectively suppresses chronic inflammation pathways, including the TGFbeta signaling pathway. As a result, it presents a promising therapeutic strategy as a single agent and opportunity for combination therapy with metabolic inhibitors in treating organ fibrotic diseases.
Gyre is also advancing a diverse pipeline through its indirect controlling interest in Gyre Pharmaceuticals, including ETUARY therapeutic expansions, F573, F528, and F230.
Company Details
- Employees
- 13
- Address
- 12770 High Bluff Drive,
- Industry
- Biotechnology Research
- NAICS
-
Research and Development in Biotechnology (except Nanobiotechnology)
- Website
- https://www.gyretx.com/
- HQ
- San Diego , CA
Gyre Therapeutics Questions
Gyre Therapeutics's website is https://www.gyretx.com/
Gyre Therapeutics's LinkedIn profile is https://www.linkedin.com/company/gyre-therapeutics
Gyre Therapeutics has
13 employees.
View email and phone details for 13
employees at Gyre Therapeutics.
Gyre Therapeutics's industry is
Biotechnology Research
Gyre Therapeutics's top competitors are
Anchor Logics,
Catalyst Biosciences,
Cero Therapeutics, Inc.,
Uniquity Bio,
Ars Pharmaceuticals, Inc.,
Qpex Biopharma, Inc.,
Gni Group Ltd.,
Gyre Pharmaceuticals,
Immunitybio, Inc.,
Vertex Pharmaceuticals.
Gyre Therapeutics's categories are Biotechnology Research
