Kurome Therapeutics is developing therapies that target cancer cells that have co-opted immune signaling pathways in order to avoid destruction by traditional therapeutic agents and subvert adaptive resistance mechanisms.
Kurome Therapeutics is a preclinical stage company that is developing a series of IRAK1/4, panFLT3 inhibitors. Preclinical studies have demonstrated:
-Broad range of efficacy in MDS and AML patient-derived cell lines
-Synergy with Venclexta® (Venetoclax) to improve Venclexta® potency
-Identification of a biomarker that correlates with prognosis in AML patients and maximal activation of immune signaling through this pathway in AML cells
-Increased overall survival in cell line and patient-derived xenograft models, well beyond that of existing FLT3 inhibitors
-Maintenance of complete efficacy even in settings of adaptive resistance to FLT3 inhibitors and in settings of FLT3 mutations
Kurome Therapeutics is founded on research developed in the laboratory of Dr. Daniel Starczynowski at Cincinnati Children's Hospital Medical Center in collaboration with the National Center for Advancing Translational Sciences (NCATS) at the NIH.
Company Details
- Employees
- 4
- Founded
- -
- Address
- 3536 Edwards Road Suite 100, Cincinnati,ohio 45208,united States
- Phone
- 513-445-3852
- in****@****etx.com
- Industry
- Biotechnology Research
- NAICS
-
Research and Development in Biotechnology (except Nanobiotechnology)
- Website
- kurometherapeutics.com
- Keywords
- oncology, therapeutics, drug development, diagnostics, biomarkers, IRAK inhibitors, FLT3 inhibitors, cancer, structure-based drug design, start-up.
- HQ
- Cincinnati, Ohio
Kurome Therapeutics, Inc. Questions
Kurome Therapeutics, Inc.'s helpline number is 513-445-3852
Kurome Therapeutics, Inc.'s website is kurometherapeutics.com
Kurome Therapeutics, Inc.'s LinkedIn profile is https://www.linkedin.com/company/kurome-therapeutics
Kurome Therapeutics, Inc. has
4 employees.
View email and phone details for 4
employees at Kurome Therapeutics, Inc..
Kurome Therapeutics, Inc.'s industry is
Biotechnology Research
Kurome Therapeutics, Inc.'s top competitors are
Lamassu Biotech,
Eikonoklastes Therapeutics, Inc.,
Convelo Therapeutics, Inc,
Clarametyx Biosciences,
Neucore Bio,
Monarch Therapeutics, Inc.,
Sermonix Pharmaceuticals,
Allinaire Therapeutics,
Journey Biosciences,
Novelmed.
Kurome Therapeutics, Inc.'s support email address is info@kurometx.com
Kurome Therapeutics, Inc.'s categories are Biotechnology Research
Kurome Therapeutics, Inc.'s founding year is 2019
