OLIGOMED - Oligonucleotides for Medical Applications Company Profile, Contacts & Intelligence

ResearchThese Needs by: (1) Uniting World-class Academic and Private Sector Expertise in on Chemistry31 employees
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31
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OLIGOMED - Oligonucleotides for Medical Applications Overview

The multipartner, multidisciplinary project OLIGOMED addresses urgent needs in healthcare, in particular cancer, Huntington's Disease and cardiovascular diseases. We apply cutting edge oligonucleotide technology to find innovative solutions and create a novel platform for personalised medicine. NEED - The use of synthetic oligonucleotides (ONs- short DNA or RNA strands) in the treatment of genetic diseases is a rapidly growing field, and the most promising alternative to gene therapy or small molecules. - Most pharmaceutical companies shift from in-house platform development to product-specific licensing and co-development to get ON based therapies past clinical trials. - There is a growing and currently unmet need for a combined academic and industry-based multidisciplinary research to further advance the field by bringing together the separated and fragmented R&D efforts of diverse ON technologies. SOLUTION - We will address these needs by: (1) uniting world-class academic and private sector expertise in ON chemistry, bio-analysis and medical applications; (2) developing a next generation ON platform technology based on combining tailored synthetic ONs with smart delivery; (3) optimising ON therapies through testing in medicinal environment. - We will use these novel ON technologies to develop innovative treatment options for high-impact genetic diseases, i.e. Huntington’s disease, cardiovascular diseases and cancer. IMPLEMENTATION - Our European intersectoral and multidisciplinary research and training network is structured in four work packages and employs 15 Early Stage Researchers (ESRs). - The project will deliver: (1) highly skilled scientific staff required to fully exploit ON therapeutics for personalised medicine; (2) top-class training in organic and chemoenzymatic synthesis, ON analysis, and biomedical/medicinal testing; (3) transferable skills courses, specific industry relevant workshops and public engagement activities.

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These Needs by: (1) Uniting World-class Academic and Private Sector Expertise in on Chemistry
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