RCTs is a French and International Full-Service CRO with more than 30 years of experience and over 700 projects conducted: clinical studies from phase I to phase IV, real-life or public health impact studies, medical and administrative assessments of SNDS (National Health Data System) databases, in various therapeutic areas (oncology, diabetes, cardiology, rheumatology, infectious diseases, central nervous system, vaccines...), for drug and medical device manufacturers, as well as for academic sponsors, institutions, learned societies and patient associations. Besides, RCTs has an expertise in clinical evaluations (CEP and CER) and regulatory consulting for medical devices.
It is also a stable company whose staff annual renewal rate is less than 10% and the 5 main managers are associates (Frédéric Mistretta, Morgane Champiot, Audrey Lajoinie, Flavien Roux and Didier Not).
IT tools (eCRF, IWRS, ePRO, eTMF, CTMS) are being constantly adapted to the constraints and evolutions of the business and regulations. These tools are developed and maintained by ClinInfo, our daughter company (http://www.clininfo.fr/).
RCTs is also co-founder and shareholder of PSN Research LLC (http://psnresearch.com/), owned by 7 European CROs and one US CRO (France, Germany, Italy, Denmark, Spain, Netherlands, Great Britain, USA). This structure provides you with a unique added value across all these territories and even beyond, through preferred partners in countries not directly covered by PSN Research's parent companies.
Specializations: Clinical studies, Pharmaco-epidemiology, Health economics, Medical Devices, Consulting, Medical Writer, Clinical Evaluation (CEP, CER), CRO, eCRF, IWRS, ePRO and eTMF.
Outcome domains measured in randomized controlled trials of physical activity for older adults: a rapid review International Journal of Behavioral Nutrition and Physical Activity
An assessment of randomized controlled trials (RCTs) for non-communicable diseases (NCDs): more and higher quality research is required in less developed countries Nature
Systematic review of strengths and limitations of Randomized Controlled Trials for non-pharmacological interventions in mild cognitive impairment: Focus on Alzheimer's disease ScienceDirect.com
Framework for the synthesis of non-randomised studies and randomised controlled trials: a guidance on conducting a systematic review and meta-analysis for healthcare decision making BMJ Evidence-Based Medicine
A systematic review of randomisation method use in RCTs and association of trial design characteristics with method selection BMC Medical Research Methodology
The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials ScienceDirect.com
Randomized controlled trials on promoting self-care behaviors among informal caregivers of older patients: a systematic review and meta-analysis BMC Geriatrics
Agreement of treatment effects from observational studies and randomized controlled trials evaluating hydroxychloroquine, lopinavir-ritonavir, or dexamethasone for covid-19: meta-epidemiological study The BMJ
Early versus delayed mobilization for arthroscopic rotator cuff repair (small to large sized tear): a meta-analysis of randomized controlled trials BMC Musculoskeletal Disorders
Statistical methods for the analysis of adverse event data in randomised controlled trials: a scoping review and taxonomy BMC Medical Research Methodology
Appropriate statistical methods for analysing partially nested randomised controlled trials with continuous outcomes: a simulation study BMC Medical Research Methodology
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