Vulcan Biologics

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Our synthetic biology platform programs commensal microbes to make medicine in vivo, delivering medicine precisely where it is needed in the body. In simple terms, MICROBES MAKE MEDICINE – my microbes make my medicine, and your microbes make your medicine. Our initial proof of concept is celiac disease, a common immune-related inflammatory disease of the small intestine caused by gluten, by demonstrating tolerance to gluten exposure as gut microbes continuously make the peptide therapy ($690 million market). Currently, there is no treatment option and patients must adhere to a strict, lifelong gluten-free diet to manage celiac disease. Our pipeline also targets metabolic disorders by locally delivering incretin metabolic hormones to tackle obesity and diabetes (multi-billion-dollar market). Beyond this, our platform enables partners to produce custom proteins/peptides to substantially reduce manufacturing costs, increase efficacy, reduce toxicity, and secure new intellectual property. Vulcan Biologics was co-founded by repeat founder Prof. Michael Koeris (Sample6 [founder, exit], BiomX, DARPA BTO) and Dr. Brian Green (Verenium [now part of BASF], Sample6, Joule).

Company Details

Founded
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Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
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