Xtalpi Inc.

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We are a quantum physics-based, AI-powered drug R&D company with the mission to revolutionize drug discovery and development by improving the speed, scale, novelty and success rate. With operations in both China and the U.S., we strive to deploy the best capabilities and resources available to us in each market to meet the needs of our customers and collaborators. Beyond our team’s domain expertise and creative thinking, the key to our mission is the integrated technology platform, which combines the mutually informing and reinforcing cloud supercomputing-powered in silico tools and our wet lab with robotic automation, and enables discovery and development of innovative therapeutics at a pace and scale beyond traditional alternatives. We are among the pioneering AI-powered drug R&D companies in the world that have established a platform with an iterative feedback loop between quantum physics-based dry lab and wet lab capabilities, according to Frost & Sullivan. With our platform designed to improve dry lab calculations with experimental data generated by the wet lab and enhance the efficiency of the wet lab by insights derived from dry lab calculations, we believe that we are well positioned at this moment where the combination of AI, computing power, data and automation is becoming increasingly critical for pharmaceutical development. Since our founding, we have received investments and support from world-renowned investors, and we believe this blue-chip shareholder base is a testament to our capabilities and prospects.

Company Details

Employees
251
Founded
-
Address
245 Main St,
Email
co****@****lpi.com
Industry
Biotechnology Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology)
Website
xtalpi.com
HQ
Cambridge, Massachusetts
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News

XtalPi Holdings Limited to Announce 2025 Interim Results on August 27, 2025 - Yahoo Finance

XtalPi Holdings Limited to Announce 2025 Interim Results on August 27, 2025 Yahoo Finance

XtalPi Holdings Announces 2025 Interim Results - Financial Times

XtalPi Holdings Announces 2025 Interim Results Financial Times

XtalPi Holdings To Announce Interim Results August 27 - Quantum Zeitgeist

XtalPi Holdings To Announce Interim Results August 27 Quantum Zeitgeist

XtalPi Unveils Ailux: A New Chapter in AI-Powered Biologics Discovery - PR Newswire

XtalPi Unveils Ailux: A New Chapter in AI-Powered Biologics Discovery PR Newswire

XtalPi and Parthenon Enter Into AI-Powered Antibody Discovery Partnership - PR Newswire

XtalPi and Parthenon Enter Into AI-Powered Antibody Discovery Partnership PR Newswire

XtalPi Launches Computational Chemistry Software for Drug Discovery: XMolGen and XFEP - PR Newswire

XtalPi Launches Computational Chemistry Software for Drug Discovery: XMolGen and XFEP PR Newswire

AI Drug R&D Startup XtalPi Announces Over 300 Million Series C Investment Led by SoftBank Vision Fund, PICC Capital, and Morningside - PR Newswire

AI Drug R&D Startup XtalPi Announces Over 300 Million Series C Investment Led by SoftBank Vision Fund, PICC Capital, and Morningside PR Newswire

XtalPi Announces Collaboration with Lilly, Using AI + Robotics to Uncover First-in-class Therapeutics - PR Newswire

XtalPi Announces Collaboration with Lilly, Using AI + Robotics to Uncover First-in-class Therapeutics PR Newswire

XtalPi Inc. Unveils "XtalPi Intelligent Automation" and Announces New Automation Facility in Shanghai - PR Newswire

XtalPi Inc. Unveils "XtalPi Intelligent Automation" and Announces New Automation Facility in Shanghai PR Newswire

XtalPi and CK Life Sciences to collaborate in AI-empowered tumour vaccine research and development, opening a new paradigm for scientific innovation - PR Newswire

XtalPi and CK Life Sciences to collaborate in AI-empowered tumour vaccine research and development, opening a new paradigm for scientific innovation PR Newswire

XtalPi and Signet Expand AI Drug Discovery Collaboration to Novel Cancer Target - PR Newswire

XtalPi and Signet Expand AI Drug Discovery Collaboration to Novel Cancer Target PR Newswire

XtalPi Announces Research Collaboration with Janssen - PR Newswire

XtalPi Announces Research Collaboration with Janssen PR Newswire

Merck & XtalPi Collaboration Optimizes Drug Formulations with AI-Powered Techniques - PR Newswire

Merck & XtalPi Collaboration Optimizes Drug Formulations with AI-Powered Techniques PR Newswire

Ailux Biologics, a Division of XtalPi, Enters into a License Agreement with Janssen Biotech on Biologics AI Platform - PR Newswire

Ailux Biologics, a Division of XtalPi, Enters into a License Agreement with Janssen Biotech on Biologics AI Platform PR Newswire

XtalPi Announces Strategic Collaboration with Porton to Offer Prediction-Guided Crystallization and Drug Solid-State Research Services - PR Newswire

XtalPi Announces Strategic Collaboration with Porton to Offer Prediction-Guided Crystallization and Drug Solid-State Research Services PR Newswire

XtalPi and Pfizer Expand Strategic Collaboration to Advance AI-Driven Drug Discovery and Materials Science Simulations - PR Newswire

XtalPi and Pfizer Expand Strategic Collaboration to Advance AI-Driven Drug Discovery and Materials Science Simulations PR Newswire

XtalPi and DoveTree Announce Landmark $6 Billion AI Drug Discovery Collaboration - PR Newswire

XtalPi and DoveTree Announce Landmark $6 Billion AI Drug Discovery Collaboration PR Newswire

Pfizer expands AI-powered small-molecule discovery collab with XtalPi - Fierce Biotech

Pfizer expands AI-powered small-molecule discovery collab with XtalPi Fierce Biotech

XtalPi and Kula Bio Forge Multi-Million USD Collaborative R&D Agreement to Advance AI-Driven Microbial Fertilizers in China and the Middle East - PR Newswire

XtalPi and Kula Bio Forge Multi-Million USD Collaborative R&D Agreement to Advance AI-Driven Microbial Fertilizers in China and the Middle East PR Newswire

XtalPi and Sinar Mas Multiartha Launch Strategic Partnership to Revolutionize AI Across Asia-Pacific - PR Newswire

XtalPi and Sinar Mas Multiartha Launch Strategic Partnership to Revolutionize AI Across Asia-Pacific PR Newswire

Development and Comprehensive Benchmark of a High-Quality AMBER-Consistent Small Molecule Force Field with Broad Chemical Space Coverage for Molecular Modeling and Free Energy Calculation - ACS Publications

Development and Comprehensive Benchmark of a High-Quality AMBER-Consistent Small Molecule Force Field with Broad Chemical Space Coverage for Molecular Modeling and Free Energy Calculation ACS Publications

Tale of Two Polymorphs: Investigating the Structural Differences and Dynamic Relationship between Nirmatrelvir Solid Forms (Paxlovid) - ACS Publications

Tale of Two Polymorphs: Investigating the Structural Differences and Dynamic Relationship between Nirmatrelvir Solid Forms (Paxlovid) ACS Publications

XtalPi Inc. Announces Strategic Research Collaboration with Pfizer Inc. to Develop Artificial Intelligence-Powered Molecular Modeling Technology for Drug Discovery - PR Newswire

XtalPi Inc. Announces Strategic Research Collaboration with Pfizer Inc. to Develop Artificial Intelligence-Powered Molecular Modeling Technology for Drug Discovery PR Newswire

Hit Identification Driven by Combining Artificial Intelligence and Computational Chemistry Methods: A PI5P4K-β Case Study - ACS Publications

Hit Identification Driven by Combining Artificial Intelligence and Computational Chemistry Methods: A PI5P4K-β Case Study ACS Publications

A Cloud Computing Platform for Scalable Relative and Absolute Binding Free Energy Predictions: New Opportunities and Challenges for Drug Discovery - ACS Publications

A Cloud Computing Platform for Scalable Relative and Absolute Binding Free Energy Predictions: New Opportunities and Challenges for Drug Discovery ACS Publications

AI Biotech XtalPi Closes Series B Round Funding from Sequoia China, Google, and Tencent - PR Newswire

AI Biotech XtalPi Closes Series B Round Funding from Sequoia China, Google, and Tencent PR Newswire

Chinese drug developer XTalPi surges on US$6 billion deal - South China Morning Post

Chinese drug developer XTalPi surges on US$6 billion deal South China Morning Post

Effect of Polymer Additives on the Crystal Habit of Metformin HCl - Bellucci - 2023 - Small Methods - Wiley Online Library

Effect of Polymer Additives on the Crystal Habit of Metformin HCl - Bellucci - 2023 - Small Methods Wiley Online Library

Prediction of the Relative Free Energies of Drug Polymorphs above Zero Kelvin | Crystal Growth & Design - ACS Publications

Prediction of the Relative Free Energies of Drug Polymorphs above Zero Kelvin | Crystal Growth & Design ACS Publications

Eli Lilly, XtalPi ink $250M deal for AI-powered drug discovery - Fierce Biotech

Eli Lilly, XtalPi ink $250M deal for AI-powered drug discovery Fierce Biotech

Templated Nucleation of Clotrimazole and Ketoprofen on Polymer Substrates - ACS Publications

Templated Nucleation of Clotrimazole and Ketoprofen on Polymer Substrates ACS Publications

AI drug miner XtalPi strikes gold with $400M infusion, its 2nd VC megaround in a year - Fierce Biotech

AI drug miner XtalPi strikes gold with $400M infusion, its 2nd VC megaround in a year Fierce Biotech

ABB Robotics partners with XtalPi to build intelligent automated laboratories - ABB

ABB Robotics partners with XtalPi to build intelligent automated laboratories ABB

XtalPi scores landmark deal for AI drug discovery - thebambooworks.com

XtalPi scores landmark deal for AI drug discovery thebambooworks.com

XtalPi and ABB Robotics to automate laboratory workstations with GoFa cobots - The Robot Report

XtalPi and ABB Robotics to automate laboratory workstations with GoFa cobots The Robot Report

AI drug researcher XtalPi lists in Hong Kong amid U.S.-China rivalry - Nikkei Asia

AI drug researcher XtalPi lists in Hong Kong amid U.S.-China rivalry Nikkei Asia

Tencent-Backed AI Drug Discovery Startup Xtalpi Rises In Hong Kong Debut - Forbes

Tencent-Backed AI Drug Discovery Startup Xtalpi Rises In Hong Kong Debut Forbes

Emerging Landscape of Computational Modeling in Pharmaceutical Development - ACS Publications

Emerging Landscape of Computational Modeling in Pharmaceutical Development ACS Publications

Pfizer launches new collaboration with XtalPi for AI drug modeling - Fierce Biotech

Pfizer launches new collaboration with XtalPi for AI drug modeling Fierce Biotech

China AI biotech XtalPi lands $15M from Sequoia, Google, Tencent - Fierce Biotech

China AI biotech XtalPi lands $15M from Sequoia, Google, Tencent Fierce Biotech

Deal Analysis: XtalPi’s (QuantumPharm) $126.7m IPO on HKEX - FinanceAsia

Deal Analysis: XtalPi’s (QuantumPharm) $126.7m IPO on HKEX FinanceAsia

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