Verified email-pattern data for Activity Signaling is currently limited. You can still use the company insights and contact sections below.
Recombinant Rabbit Monoclonal anti-Npas4 Antibody
We have developed an anti-Npas4 recombinant rabbit monoclonal antibody with high specificity demonstrated in Npas4 KO mice. This Npas4 antibody can be used to mark active neurons in brain slices and in primary cultures. The Ab has worked well in all methods tested, including Western blotting, immunohistochemistry, immunocytochemistry, ChIP-Seq and iDISCO whole brain staining.
Npas4 as a Marker of Recent Neuronal Activity
Neuronal activity engages biochemical signaling pathways that produce alterations in gene expression leading to long-term adaptive changes in neurons that are fundamental to behavioral plasticity. Thus, immediate-early gene (IEG) induction is commonly used to visualize recent neuronal activity. However, the IEGs traditionally used to mark neuronal activity (e.g., arc, cfos and egr1/zif268) are also turned on by extrinsic factors such as neurotrophins and neuromodulators that raise cAMP. In contrast, the neuron-specific IEG npas4is strongly induced by neuronal activity, but does not respond to these other factors (Lin et al., 2008). Further, Npas4 expression is more rapid and transient than other IEGs (Ramamoorthi et al., 2011). This tight tuning to neuronal activity makes Npas4 an ideal marker of neuronal activity in the brain.
Company Details
- Address
- San Diego, California 92127, Us
- Industry
- Biotechnology Research
- Website
- http://www.activitysignaling.com
- Keywords
- Activity Business Center of Hawaii.
- HQ
- SAN DIEGO, CALIFORNIA
Activity Signaling Questions
Activity Signaling's website is http://www.activitysignaling.com
Activity Signaling's LinkedIn profile is https://www.linkedin.com/company/activity-signaling
Activity Signaling's industry is
Biotechnology Research
Activity Signaling's top competitors are
Stream Trip,
Truecast Media Alliance,
Livestream,
Activity Business Center Of Hawaii,
Livestream Junkies,
Translucence Biosystems,
Hooshmand Law Group,
Agence Green Activity,
Livestream Prom,
Green Tv Productions & Event S.
Activity Signaling's categories are Biotechnology Research
Explore related pages
Related company profiles:
Free Chrome Extension
Find emails, phones & company data instantly
Find verified emails from LinkedIn profiles
Get direct phone numbers & mobile contacts
Access company data & employee information
Works directly on LinkedIn - no copy/paste needed
Aero Online
Your AI prospecting assistant
Select data to include:
Total price:
$0.00
0 records × $0.02 per record
How It Works
Get a Free Account
Sign up for a free account. No credit card required. Up to 10 free credits.
Search the #1 Contact Database
Get contact details of over 750M+ profiles across 60M companies – all with industry-leading accuracy. Sales Navigator and Recruiter users, try out our Email Finder Extension.
Use our AI-Powered Email Finder
Find business and personal emails and mobile phone numbers with exclusive coverage across niche job titles, industries, and more for unparalleled targeting. Also available via our Contact Data API.