Cell Signaling and Drug Discovery Group (Waaler)

Cell signaling and drug discovery group (waaler) email format

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Our research group at Oslo University Hospital is dedicated to advancing the understanding of tankyrase 1 and tankyrase 2 (TNKS1/2), key enzymes in the PARP family that regulate protein function, interactions, and degradation through ADP-ribosylation and downstream signaling. TNKS1/2 play crucial roles in controlling WNT/β-catenin and Hippo signaling pathways, both of which are central to disease mechanisms such as cancer, immune evasion, and fibrosis.
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