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KINE SCIENCES is a company that researches and develops ultra-small immune-peptide drugs based on functional immunology for chronic neuroinflammatory and autoimmune diseases. We were the first to identify the anti-inflammatory function of ERDR1, and based on this, we have independently established a development process for immune-modulating functional immune-peptide drugs derived from cytokine-based peptides. We possess a comprehensive peptide library consisting of approximately 200 diverse peptide candidates. We have 6 assets with 19 indications in the pipeline including Rheumatoid Arthritis, Inflammatory Bowel Disease, Alzheimer’s Disease and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). Our ultra-small immune-peptides offer differentiated advantages, including excellent pharmacokinetic and pharmacodynamic (long PD effect) profiles, low immunogenicity and antigenicity, cost-effective production, and the potential for oral administration.
We are primarily focused on our lead asset, KINE-101, an ultra-small peptide (<1 kDa) composed of 9 amino acids, targeting Treg cells as a treatment candidate for CIDP. Following the successful completion of a Phase I clinical trial in healthy volunteers in the US, which demonstrated a good safety profile, a Phase Ib/IIa clinical study is currently underway in Korea with CIDP patients who have previously received at least one frontline treatment regimen (first patients dosed).
In addition, KINE-501, a post-modification form of KINE-101 designed to enhance therapeutic efficacy, is a candidate for Alzheimer's disease treatment, targeting microglial cells, the immune cells of the brain. KINE-501 can cross effectively the blood-brain barrier (BBB) and has the unique ability to simultaneously induce the removal of amyloid-beta and exert anti-inflammatory and antioxidant effects.
We are currently seeking a partner for the co-development, licensing or funding of KINE-101 and KINE-501.
Company Details
- Employees
- 4
- Founded
- -
- Industry
- Biotechnology Research
- Website
- http://kinesciences.com/
- Keywords
- Sheffield.
Kine Sciences Co., Ltd. Questions
KINE SCIENCES Co., Ltd.'s website is http://kinesciences.com/
KINE SCIENCES Co., Ltd.'s LinkedIn profile is https://www.linkedin.com/company/kine-sciences-co-ltd
KINE SCIENCES Co., Ltd. has
4 employees.
View email and phone details for 4
employees at KINE SCIENCES Co., Ltd..
KINE SCIENCES Co., Ltd.'s industry is
Biotechnology Research
KINE SCIENCES Co., Ltd.'s top competitors are
Propria.io,
Chong Kun Dang Pharm.,
Biocodex,
Sse Renewables,
Fern Talent,
Chardan,
Colorcon®.
KINE SCIENCES Co., Ltd.'s categories are Biotechnology Research
KINE SCIENCES Co., Ltd.'s founding year is 2012
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Top KINE SCIENCES Co., Ltd. Employees
-
hyoshin Kim
Bd Assistant Manager At Kine Sciences
Seoul, South Korea, Korea, Republic Of -
-
Sungwon Cho
Business Development Manager At Kine…
South Korea, Korea, Republic Of
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