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RNAble is a preclinical biotechnology company developing a potent small-molecule inhibitor targeting FTO, a key driver of oncogenic RNA biology. Mechanistic studies have led to the identification of a specific biomarker that predicts pan-cancer sensitivity to the inhibitor across both hematological and solid malignancies.
Key highlights of RNAble's lead candidate:
• Demonstrates strong in vivo efficacy and superior antitumor activity compared to standard-of-care therapies in AML models.
• Shows promising efficacy in preclinical models of biomarker-selected solid tumors.
• Features a novel, validated mechanism of action that induces cancer cell death via RNA-mediated mitotic catastrophe followed by apoptosis, with potential to overcome resistance to current therapies.
• Exhibits strong oral bioavailability and a favorable safety profile.
• Expected IND submission in 2026.
Company Details
- Employees
- 6
- Founded
- -
- Address
- Ilan Ramon Street 2, 3rd Floor,israel
- Industry
- Biotechnology
- Keywords
- RNA, Cancer, Small Molecule.
- HQ
- Ness Ziona
Rnable Questions
RNAble's website is https://www.futurx.co.il/portfolio/rnable/
RNAble's LinkedIn profile is https://il.linkedin.com/company/rnable
RNAble has
6 employees.
View email and phone details for 6
employees at RNAble.
RNAble's industry is
Biotechnology
RNAble's top competitors are
Biolinerx,
Mitocarex Bio Ltd,
Circuit-Bio Ltd,
Catchme Therapeutics,
Scinai Immunotherapeutics Ltd.,
Aummune,
Futurx,
Cytoreason,
Kanso Diagnostics,
Epeius Pharma.
RNAble's categories are Biotechnology
RNAble's founding year is 2021
Top RNAble Employees
-
-
Guy Biber
Research Scientist
Rishon Lezion, Center District, Israel, Israel -
Reut Eshel
Senior Scientist | Drug Development |…
Rehovot, Center District, Israel, Israel -
Rotem Karni
Professor And Entrepreneur, Department…
Jerusalem District, Israel, Israel2ekmd.huji.ac.il, huji.ac.il
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