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Sentrimed is a clinical-stage biopharmaceutical company creating safer, orally dosed oncology therapies that target the cancer biomarker podoplanin (PDPN). PDPN is a transmembrane glycoprotein receptor that enables cancer cells to proliferate and migrate. This biomarker appears early in cancer transformation, persists through malignant progression, and causes poor clinical outcomes. As a result, targeting PDPN could represent an important advancement in the profiling and treatment of cancer.
The Company’s lead product candidate, MASL, is an orally administered therapeutic that targets the PDPN receptor. MASL is a leader in a new drug class called oncolectins and represents a novel approach to addressing common challenges in oncology treatments, including drug resistance and highly immunosuppressive tumor microenvironments—which contribute to high recurrence rates and poor patient outcomes.
Blocking PDPN by MASL inhibits cancer by altering pathways critical to tumor growth, invasion, evasion and resistance - specifically RAS-GTP, TGF-β SMAD, JAK-STAT, and WNT/β-catenin. Additionally, MASL triggers necrotic cell death, which causes host anti-tumor immune responses.
Company Details
- Employees
- 6
- Founded
- -
- Address
- South Jersey Technology Park At Rowan University,
- Industry
- Biotechnology Research
- Website
- http://www.sentrimed.com
- Keywords
- Cambridge.
- HQ
- Mullica Hill, NJ
Sentrimed Questions
Sentrimed's website is http://www.sentrimed.com
Sentrimed's LinkedIn profile is https://www.linkedin.com/company/sentrimed
Sentrimed has
6 employees.
View email and phone details for 6
employees at Sentrimed.
Sentrimed's industry is
Biotechnology Research
Sentrimed's top competitors are
Sentrim Hotels & Lodges,
Genetic Engineering & Biotechnology News,
Linnaeus Therapeutics, Inc.,
Emzingo & Emzingou,
Sopa Lodges,
Integerbio,
Applied Therapeutics, Inc.,
Ima New York,
Arab Conference At Harvard,
Mariposa.
Sentrimed's categories are Biotechnology Research
Sentrimed's founding year is 2011
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Top Sentrimed Employees
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-
Chris Leonard
Secretary At Sentrimed Inc.
Brookline, Massachusetts, United States, United States2gmail.com, bostonpublicschools.org -
Ariel C. Yin
Molecular Cell Biology And Neuroscience…
Greater Philadelphia, United States1urmc.rochester.edu
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