Vasa Therapeutics

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Vasa Therapeutics is a San Diego-based, private biotechnology company committed to the discovery and development of therapeutics that target pathophysiology of cardiovascular aging. Vasa Therapeutics has three active preclinical programs: 1. VS-041 is the first personalized medicine-based treatment of HFpEF. VS-041 shows robust reduction of cardiac fibrosis in a preclinical HFpEF model and inhibits release of signaling collagen fragments, such as PRO-C6, that mediate fibroinflammatory responses and are biomarkers of worse outcomes in HFpEF patients. Phase 1 clinical trial of VS-041 is planned for 2024. 2. Long acting apelin peptide analogs for combination treatment with incretins in obesity patients at risk for skeletal muscle loss or cardiovascular disease. As a monotherapy, long acting apelin agonists could also be beneficial in muscle atrophy, heart failure, chronic kidney disease, and peripheral artery disease. 3. A best-in-class inhibitor of CamKIId for heart failure and life-threatening arrhythmias.

Company Details

Employees
8
Founded
-
Industry
Biotechnology Research
Website
http://www.vasatherapeutics.com
Keywords
Drug discovery, Cardiovascular disease, Aging, Heart Failure with preserved Ejection Fraction, Sarcopenia, Obesity, Chronic Kidney Disease, Peripheral Artery Disease, Arrhythmia, Longevity.
Competitors
Crinetics Pharmaceuticals, Travere Therapeutics, Ferdia Therapeutics LLC, Artery Therapeutics, Inc., Orphinic Scientific, Seal Rock Therapeutics, Biolexis Therapeutics, Inc., Quotient Sciences, BTB Therapeutics, Inc., eXIthera Pharmaceuticals LLC.
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