Timothy Chapman, Phd Email & Phone Number

Carlsbad, Ca, Us

San Diego, California, United States

• Executed end-to-end Benchling R&D and In Vivo implementations across a diverse customer base of startups to mid-markets, developing tailored solutions, leading training, and building for continued success and expansion.• Relied on a strong scientific background to translate customer workflows and requirements to configurations, including antibody and gene therapy development and bioprocessing, in vivo pharmacology, ASO chemistry, and donor eligibility and screening.• Led an early GxP rollouts for Benchling for 200+ users, aligning with 3rd-party validation consultants on URS, RA, PQ, and summary documentation. • Developed a best practice data model for Bioanalytical workflows based on FDA and EMA guidelines using out-of-the-box configurations• Developed SQL-based operational and analytical dashboards for stability studies, donor monitoring, animal colony and inventory management, and more.

Provided technical expertise, application support, customer training, and pre- and post- sales support for near-infrared imagers and fluorescent-based protein expression assays.

• Oversaw all aspects of projects that implemented and validated track and trace software solutions for pharmaceutical clients to comply with worldwide drug serialization laws. • Developed and executed cross-functional project plans to integrate client’s serialization and supply chain efforts with their trading partners. • Led regular team meetings with client and other key stakeholders to update progress and risks and ensure clear actions were delegated and documented. Acted as the direct liaison for client’s IT, QA, and Supply Chain teams. • Remotely managed IT/software specialists, validation consultants, and pharmaceutical serialization experts across many time zones to produce high quality deliverables on time and within budget.

• Developed ‘personalized’ mouse models using CRISPR/Cas9 to replicate rare, de novo mutations identified in patients with autism and neurodevelopmental disorders. • Identified biomarkers and performed functional assays using patient-derived fibroblasts, cerebral organoids, and primary mouse cortical neurons.• Analyzed mouse models for behavioral phenotypes analogous to autism. • Conducted preclinical treatment with a proprietary Phase II oral compound to treat glutamatergic receptor deficiency, abnormal anxiety, and impaired learning in ‘personalized’ mouse model. • Managed project funded by Roche Pharma to analyze a mouse model for schizophrenia. • Developed and synthesized molecular inversion probes to target and sequence mutational hotspots and risk alleles in autism. • Drafted NIH grants, prepared manuscripts, and regularly presented research progress.

Doctoral Thesis: Interactions of Aging, Inflammation, and Neuronal Function • Investigated how infection in aged rodents alters multiple forms of synaptic plasticity, neuronal growth factor expression, and ion channel surface expression in the hippocampus using electrophysiology, pharmacology and standard molecular biology techniques. • Presented research regularly in department workshops and annually at Society for Neuroscience conferences.• Managed and trained research technicians on multiple projects and acted as a mentor for the Undergraduate Research Opportunity Program.

• Cloned microRNA regulatory sequence elements in GFP expression vectors to visualize microRNA expression during human embryonic stem cell differentiation.• Maintained stem cell culture lines and related reagents and equipment.

• Performed quality control assays on reagents and kits involving quantitative RT-PCR, 5′ and 3′ RACE, and cDNA cloning. • Prepared and purified large-yield RNA standards by size-exclusion liquid chromatography and NMR spectroscopy. • Transferred technologies from R&D and acquired companies and trained members of the manufacturing team.

Ph.D., Neuroscience And Psychology

Thesis: Interactions of Aging, Inflammation, and Neuronal Function: Synaptic Plasticity in Older Rats is Altered Following a Peripheral.

Master Of Arts (Ma), Psychology

Bachelor Of Science (Bs), Molecular Biology