Alexandre Rebuffat, Ph.D. Email & Phone Number

Caslano, Switzerland

I am a driven and creative scientific professional with a reputation for advancing projects with integrity and ingenuity. I can offer a rapid knowledge transfer through a wide range of expertise in the various fields relevant to Bioresource Technology to enhance stewardship of natural resources. 1) bioconversion of food wastes and its valorizations.2) enzymatic hydrolyzes and different fermentation processes.3) drying methodologies for food or waste processing.4) emerging tool for separating and isolation of high-added-value compound from natural products or raw materials from Food Supply Chain Waste (i.e., chitin, vegetable protein or new alternative source of protein, biocatalyst from plant or other organisms).5) implementation of new methodologies by using functional materials for studies on soil microbiology and isolation of microorganisms of importance.6) setup of clean processes for ammonia emission mitigation in food waste composting and production of enriched soil amendments.

Manno/Gravesano, Canton Of Ticino, Switzerland

Analysis of Trends in Food Science and Technology for the implementation of innovative approaches to the food sector and biowaste management: STAYFRESH project - Natural food preservation methods for salad-cut Iceberg salad to increase storage and quality maintenance- Biocontrols and preservation of fresh-cut and ready-to-eat fruits and vegetable for improved color, texture, flavor, taste, and nutritional value maintenance-Solid state or submerged fermentation of catering food waste as long-term storage of biological wastes for raw bioresource banking or production of alternative protein from insect or mass rearing of other value organismsAnalysis of consumer food trends toward healthy food and the production of value-added bakery products:-probiotic microorganisms resistant to food-processing conditions for bakery products-fortification of flour and bread in health and disease prevention (bioactive health-promoting compounds)-Introduction to Design thinking and food innovation for improving the attractiveness of the bakery's products in children and other niche markets

Manno, Canton Of Ticino, Switzerland

- Day to Day business management: food preparation, distribution, quality control, and hygiene- Customer acquisition management: potential customer identification, advertising, marketing, customer relationship management, loyalty programs preparation, and client needs assessment

Manno/Gravesano, Canton Of Ticino, Switzerland

Co-founded a Vending distribution business as a sales channel to sell ready-to-eat fresh products such as fruits, salad, and bakery's products.From 10/2010 - 11/2013: Customer prospecting; marketing plan preparation; contract negotiation; product presentation; Excel tables implementation for day to day business management.Annual revenues: CHF 180K (2012); CHF 250K (2013); CHF 48K (2017/2018) From 12/2017 - 11/2018: Day to Day business management

Children'S Hospital, Zürich, Switzerland

Gene Therapy with recombinant Adeno-Associated Virus (rAAV) and Side Projects:-Pre-clinical studies in a mouse model for phenylketonuria: 1) Liver gene transfer by intramuscular delivery of rAAV encoding functional phenylalanine hydroxylase 2) Liver gene transfer by hydrodynamic tail vein injection of optimized liver-specific non-viral vectors 3) Skeletal muscle bioengineering with rAAV for the correction of hyperphenylalaninemia- Analysis of the physiological consequence of the low level of tetrahydrobiopterin (BH4) cofactor in a mouse model with reduced or impaired BH4 synthesis under a high-fat diet.

Oxford, United Kingdom

Genetic analysis of complex phenotypes in rodents for quantitative genetic trait loci mapping

Children'S Hospital, Bern, Switzerland

Steroids and Gene therapy, and Side Projects:1) Synthesis of steroid-peptide nucleic acid conjugates for enhanced nuclear uptake of non-viral gene delivery vector in gene therapy2)Development of cell-based assays for the screening of synthetic steroid derivatives and compounds from human biological fluids: bioprospecting of inhibitory activities for 11 beta-hydroxysteroid dehydrogenase type 1 and 2 enzymes, and activity's modulation of the glucocorticoid receptor

Certificate In Laboratory Animal Science (Ltk1 Module)

Doctor Of Philosophy - Phd, Life Sciences, Very Good (Ects Grading Scale)

Activities and Societies: Department of Nephrology and Hypertension, Children's Hospital, Prof. Felix J. FreySynthesis of polymeric agents.

Diploma In Biochemistry, Biochemistry, Good (Ects Grading Scale)

Diploma Project under the supervision of Prof. Andreas Conzelmann: analysis and role of specific lipid species in the organization.