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Aaron Farrell Email & Phone Number

Process Development Scientist II at APC
Location: Dublin, County Dublin, Ireland 8 work roles 6 schools
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Current company
APC
Role
Process Development Scientist II
Location
Dublin, County Dublin, Ireland
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Who is Aaron Farrell? Overview

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Aaron Farrell is listed as Process Development Scientist II at APC, a with 640 employees, based in Dublin, County Dublin, Ireland. AeroLeads shows a matched LinkedIn profile for Aaron Farrell.

Aaron Farrell previously worked as Upstream Process Development and Analytical Scientist II at Apc and Upstream Process Development and Analytical Scientist at Apc. Aaron Farrell holds Doctor Of Philosophy - Phd, Biochemistry And Molecular Biology from Dublin Institute Of Technology.

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APC

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Profile bio

About Aaron Farrell

I am a recent PhD graduate with an extensive background in bioscience, biotechnology, and drug development, ready to transition into the industry. I hold a BSc (Hons) in Bio-Molecular Science & Drug Development with First-Class Honours, where I gained practical experience in diverse projects, including developing a novel platelet function test, investigating protease inhibitors for African sleeping sickness, and analysing miRNA impacts on the CHO cell proteome. My expertise spans core lab techniques such as cell culture, chromatography, PCR, and ELISA.My PhD research at Technological University Dublin focused on discovering and characterising novel antimicrobial peptides from plants. Using computational biology and experimental techniques, I optimised RNA extraction methods, constructed cDNA libraries, and developed PCR primers for defensin identification and gene expression analysis. Additionally, I established protocols for total protein extraction and purification from oil-based seeds, fine-tuning buffer compositions, cell lysis, ammonium sulfate precipitation, and desalting methods.This work involved testing novel plant antimicrobial peptides on bacteria, yeast, and fungi and conducting cytotoxicity testing on mammalian cells. I also constructed and optimised plasmids for expressing a novel plant defensin in E. coli, refining codon optimisation, transformation, translation, and His-Tag Ni-NTA purification for improved yield and purity.My project demonstrated the effectiveness of a multifaceted approach to identifying defensin-like peptides. It deepened my experience with data analytics tools like Knime, R, Microsoft Visual Studio, GraphPad Prism, and Minitab, along with bioinformatics tools, including BLAST and Hidden Markov Models for sequence and structure analysis. I am also skilled in protein homology modelling, docking, and QSAR analysis.As an adaptable and driven researcher, I am excited to apply my skills to advance scientific solutions in the biotech industry.

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APC
Apc
Process Development Scientist II
Dublin, IE
Website
Employees
640
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8 roles

Aaron Farrell work experience

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Process Development Scientist Ii

Apc

Dublin, Ie

Upstream Process Development And Analytical Scientist Ii

Apc

Dublin, Ie

Upstream Process Development And Analytical Scientist

Apc

Dublin, County Dublin, Ireland

Postgraduate Researcher

Dublin, County Dublin, Ireland

My work focused on the computational identification and experimental characterisation of novel plant-derived, defensin-like proteins with antimicrobial activity. I integrated bioinformatics and QSAR (Quantitative Structure-Activity Relationship) analysis to assess genetic sequences and predict bioactive peptides. Experimental validation was conducted through gene expression analysis (qRT-PCR), protein extraction, antimicrobial efficacy testing, and mammalian cytotoxicity assessment. This was followed by recombinant protein expression of the most potent plant peptide candidate.

Sep 2018 - Mar 2024

Research Assistant

Project placement at the Royal college of Surgeons Beaumont working on the development of a novel platelet function test (platelet monitoring bio chip) to produce a cost effective, rapid, small volume platelet function assay which can detect the effect of multiple anti-platelet drugs in a single patient blood sample. The PMB assay was ran in parallel with the current gold standard, light transmission aggregometry assay. The project contained a detailed assessment and comparison of platelet function assay's performance as well as the performance of multiple anti-platelet therapies in cardiovascular disease patients

Feb 2017 - May 2017

Bachelor Of Science (Bsc) Bio-Molecular Science

This course employed an interdisciplinary approach, providing me with theoretical and practical aspects of chemical, biochemical and microbiological analysis. Core Modules- Biochemistry, Molecular Immunology, Advanced Molecular Biology, Elective Modules- Bioprocessing, Drug DevelopmentAnalytical chemistry techniques:HPLC, GC, and other chromatographic techniques (affinity/ ion exchange). NMR, and fluorescence. Biological techniques:DNA extraction/purification, western blotting, electrophoresis, bacterial and mammalian cell culture, microscopy, bioassays, ELISA, PCR (RT-PCR/qPCR), flow cytometry, blood grouping, platelet function testing, genetic transformation, food sample analysis, bioreactor setup, and aseptic technique.

Sep 2016 - May 2017
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Colleagues at APC

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6 education records

Aaron Farrell education

Applied Pharmaceutical Structural Bioinformatics, Pass With Distinction (Vg)

Activities and Societies: -Alignment sequences and database searching. -Techniques for prediction of secondary protein structure.

Pharmaceutical Bioinformatics, Pass

Activities and Societies: -Databases in Pharmaceutical Biosciences. -Molecular Descriptors, Macromolecular Descriptors. -Alignments.

Bachelor Of Science (Bsc) Bio-Molecular Science, Biochemistry And Molecular Biology, First-Class Hons

Subjects - Biotechnology: Upstream & Downstream Bioprocessing - Advanced Molecular Biology - Biochemistry - Drug Development - Molecular.

Bachelor Of Science (Bsc) Biosciences, Merit Upper Division

Subjects -Analytical biochemistry -Biotechnology - Upstream and Downstream Bioprocessing -Advanced Molecular Biology -Genetic Engineering.

FAQ

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What company does Aaron Farrell work for?

Aaron Farrell works for APC.

What is Aaron Farrell's role at APC?

Aaron Farrell is listed as Process Development Scientist II at APC.

Where is Aaron Farrell based?

Aaron Farrell is based in Dublin, County Dublin, Ireland while working with APC.

What companies has Aaron Farrell worked for?

Aaron Farrell has worked for Apc, Technological University Dublin, Dublin Institute Of Technology, and Royal College Of Surgeons In Ireland.

Who are Aaron Farrell's colleagues at APC?

Aaron Farrell's colleagues at APC include Lauren Mcsweeney, Pranav Deo, Kate Donnelly, Priya Sahadevan Syamala, Phd, and Oussal Ahmed.

How can I contact Aaron Farrell?

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What schools did Aaron Farrell attend?

Aaron Farrell holds Doctor Of Philosophy - Phd, Biochemistry And Molecular Biology from Dublin Institute Of Technology.

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