Aaron Sutherland Email & Phone Number

United Kingdom

Eurocentral

Livingston, Scotland, United Kingdom

Edinburgh, United Kingdom

Responsible for developing antibody purification protocols for scale-up into GMP manufacture in accordance to MHRA regulations.My skills include various biochemical protein purification techniques in order to produce procedures and products to the highest quality standards.

Edinburgh, United Kingdom

Glasgow, United Kingdom

My role within BioAscent Discovery Ltd lies within the automated, state of the art, compound storage and distribution facility, as a pivotal team member responsible for the organisation and coordination of process activities ensuring the successful management of client compound libraries for storage and distribution globally. As a laboratory automation/data handling specialist I am also responsible for the running and maintenance of vital pieces of robotic equipment as well as ensuring all data… Show more My role within BioAscent Discovery Ltd lies within the automated, state of the art, compound storage and distribution facility, as a pivotal team member responsible for the organisation and coordination of process activities ensuring the successful management of client compound libraries for storage and distribution globally. As a laboratory automation/data handling specialist I am also responsible for the running and maintenance of vital pieces of robotic equipment as well as ensuring all data is processed accurately and efficiently.My skills include the management of compound collections exceeding 1 million compounds. I am responsible for the registration, processing and management of new and existing compound libraries ensuring they are available for collaborative and commercial purposes. Show less

Edinburgh

GMP Production of Advanced Biologics-Cell Therapies, GMP cell production.-Responsible for the technical transfer, planning and running of manufacturing processes to cGMP of advanced biologics.-Excellent hands-on experience working with a wide variety of equipment and techniques associated with the manufacture of protein products (e.g. AKTA Pilot, ion-exchange/affinity chromatography, Tangential Flow and hollow fibre filtration systems), for diafiltration and… Show more GMP Production of Advanced Biologics-Cell Therapies, GMP cell production.-Responsible for the technical transfer, planning and running of manufacturing processes to cGMP of advanced biologics.-Excellent hands-on experience working with a wide variety of equipment and techniques associated with the manufacture of protein products (e.g. AKTA Pilot, ion-exchange/affinity chromatography, Tangential Flow and hollow fibre filtration systems), for diafiltration and concentration of product, within class B, C and D cleanrooms.-Responsible for writing and reviewing GMP documentation and participate in risk assessments associated with GMP manufacturing processes and deviation reporting. Show less

HTS ASSAY DEVELOPMENT·Managed assay development full life cycle for GPCR and lon channel targets ·Development and miniaturisation of assays (96/384 well formats) measuring receptor/ligand interactions using radioligand binding and fluorescence technologies·Monitored assay performance and troubleshooting where necessary ·Created standard operating procedures and protocols for new assays·Evaluated new laboratory automation technologies and optimised existing equipment for use… Show more HTS ASSAY DEVELOPMENT·Managed assay development full life cycle for GPCR and lon channel targets ·Development and miniaturisation of assays (96/384 well formats) measuring receptor/ligand interactions using radioligand binding and fluorescence technologies·Monitored assay performance and troubleshooting where necessary ·Created standard operating procedures and protocols for new assays·Evaluated new laboratory automation technologies and optimised existing equipment for use in HTS campaigns eg. Biomek FX platforms, HighRes Biosolutions plate replicator, Tecan Freedom EVO liquid handlersCOMPOUND LOGISTICS·Lead role in processing the integration of new chemical samples into the repository; and the distribution of the chemical collection globally·Planned, organised and forecasted the annual supply of chemicals to the site, ensuring targets would be met·Processed over 500 global customer orders on an annual basis, ensuring smooth operational efficiency ·Created strong working relations and collaborated with external suppliers (EU, India and China) and ‘internal’ customers ·Maintained and undertook troubleshooting on robotic equipment associated with running a successful chemical storage facility ·Selected to work with a global team set up to evaluate potential savings on laboratory consumables – consulting with the team and suppliers to identify key areas of cost reduction ·Compiled chemical data file formats from suppliers and associated a unique identifier, using in house sample administration software and MS Excel, prior to uploading onto inventory database Show less

·Planned and forecasted completion dates for assays under development, facilitating the construction of an annual screening timetable for senior project members ·Created the optimisation of fungal and bacterial culture conditions for the production of over-expressed enzymes; and the purification of active enzymes and peptides ·Sourced plant materials for testing through building relationships with specialist collaborators ·Contributed to a number of patents related to novel peptide… Show more ·Planned and forecasted completion dates for assays under development, facilitating the construction of an annual screening timetable for senior project members ·Created the optimisation of fungal and bacterial culture conditions for the production of over-expressed enzymes; and the purification of active enzymes and peptides ·Sourced plant materials for testing through building relationships with specialist collaborators ·Contributed to a number of patents related to novel peptide sequences discovered during purification and screening of crude seed/leaf extracts Show less