Aarón Gallego Crespo

Aarón Gallego Crespo Email and Phone Number

PhD student in Bioinformatics | Computational Biology | Cancer Omics @ University Medical Center Mainz
mainz, rheinland-pfalz, germany
Aarón Gallego Crespo's Location
Mainz, Rhineland-Palatinate, Germany, Germany
About Aarón Gallego Crespo

I'm a PhD student at Dr. med. Daniel Sasca's lab in the University Medical Center (UMC), Mainz. This position is part of the International PhD Program (IPP) from the Institute of Molecular Biology (IMB) of Mainz. My project revolves around data analysis, integration and prediction of potential therapeutic treatments for Acute Myeloid Leukemia (AML).Thanks to my Biochemistry Bachelor degree I have a solid professional training about the molecular and cellular functioning of livings systems. There I got experience with wet lab techniques such as Northern Blot, ELISA, qPCR, RNA-Seq, and NGS for polymorphisms identification. Then I started a Master degree in Genetics since I wanted to specialize in the field of human genomics and its biomedical applications. There I got the oportunity to perform my Master thesis in the Javier Martin Ibáñez Group (IPBLN-CSIC), focused on meta-GWAS and HiChIP data analysis to search interesting systemic sclerosis associated SNPs variants present in regulatory, Th17 and Naive T Cells. That was one of the most enriching experiences in my early career and thanks to that I started to be interested in bioinformatics.I specialized further into Bioinformatics by studying a Master degree in Bioinformatics at the Open University of Catalonia (UOC), learning to use computational tools for biological and clinical data analysis. I am mostly interested in Omics and gene expression data analysis and how we can learn from them to discover complex disease biomarkers and drug development.

Aarón Gallego Crespo's Current Company Details
University Medical Center Mainz

University Medical Center Mainz

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PhD student in Bioinformatics | Computational Biology | Cancer Omics
mainz, rheinland-pfalz, germany
Employees:
904
Aarón Gallego Crespo Work Experience Details
  • University Medical Center Mainz
    Phd Student
    University Medical Center Mainz Apr 2023 - Present
    Mainz, Rhineland-Palatinate, Germany
    Data analysis, integration and prediction of potential therapeutic treatments in Acute Myeloid Leukemia (AML). Assessing the effects in gene expression and its regulation of targeting EP300/CREBBP, an acetylator of histones and other proteins. Sequencing data analysis is essential in this project, acquiring experience in working with the following methods:RNA-SeqSLAM-SeqChIP-SeqPRO-SeqRIMEAcetyl-proteomics
  • Bellvitge Biomedical Research Institute - Idibell
    Biostatistician
    Bellvitge Biomedical Research Institute - Idibell Oct 2021 - Feb 2022
    Barcelona, Catalonia, Spain
    Statistical and survival analysis from a multicentre clinical database of ICU patients in the context of the ENPIC project (Evaluation of Nutritional Practices in Critical Care). Studying enteral and parenteral nutrition therapy data using methods such as binary logistic regression, Cox regression, ROC curve and Kaplan-Meier analysis. The results of this work led to communications at the 37th Congress of the Spanish Society of Clinical Nutrition and Metabolism (SENPE 2022).
  • Universitat Oberta De Catalunya (Uoc)
    Student Of Master'S Thesis
    Universitat Oberta De Catalunya (Uoc) Oct 2021 - Jan 2022
    Barcelona, Catalonia, Spain
    I performed the Master's Thesis titled "Use of R/Bioconductor packages for ChIP-Seq data functional analysis" with a grade of 8.5 . It consisted of a comparative analysis of Bioconductor packages such as ChIPpeakAnno, ChIPseeker and rGREAT in order to design a pipeline for peak annotation and DNA motif analysis of transcription factor (TF) and histones peaks data. This pipeline is suitable for analysing TF/histone ChIP-Seq data from three experimental scenarios: 1) Different biological… Show more I performed the Master's Thesis titled "Use of R/Bioconductor packages for ChIP-Seq data functional analysis" with a grade of 8.5 . It consisted of a comparative analysis of Bioconductor packages such as ChIPpeakAnno, ChIPseeker and rGREAT in order to design a pipeline for peak annotation and DNA motif analysis of transcription factor (TF) and histones peaks data. This pipeline is suitable for analysing TF/histone ChIP-Seq data from three experimental scenarios: 1) Different biological replicates, same cell line; 2) Two different conditions (eg.: healthy tissue vs. disease), same cell line; 3) Different cell lines (Eg.: GM12878). Show less
  • Instituto De Parasitología Y Biomedicina
    Research Assistant (Master Thesis)
    Instituto De Parasitología Y Biomedicina "López - Neyra" Jan 2020 - Jul 2020
    Granada, Andalusia, Spain
    I perfomed my Master's Thesis titled "Functional study of systemic sclerosis - associated genetic variants", with a grade of 9.5 . Meta-GWAS and HiChIP data processing and analysis to study the functional role of genetic variants associated with systemic sclerosis in the connectome of three subsets of CD4+ T Cells: regulatory, Th17 and Naive T Cells. This project was performed in the Javier Martín Group "Genetic basis of autoimmune diseases" (IPBLN-CSIC) (Group webpage: https://bit.ly/35wL6wz)
  • Universidad De Murcia
    Research Assistant (Bachelor Thesis)
    Universidad De Murcia Mar 2019 - Jul 2019
    Murcia, Región De Murcia, Spain
    Carrying out my Bachelor's Thesis titled "Caracterisation of tyrosine kinase receptor ErbB4 expression in the Interpeduncular Nucleus in mouse development", with a grade of 9
  • Instituto Murciano De Investigación Biosanitaria (Imib)
    Laboratory Technician (Internship)
    Instituto Murciano De Investigación Biosanitaria (Imib) Feb 2019 - Mar 2019
    Murcia Y Alrededores, España
    Performing the usual techniques in the "Genomics Platform" Laboratory at IMIB: PCR, qPCR and Next Generation Sequencing with Ion Torrent technology
  • General Universitary Hospital Reina Sofía Of Murcia. Departments Of Microbiology And Biochemistry
    Student Internship
    General Universitary Hospital Reina Sofía Of Murcia. Departments Of Microbiology And Biochemistry Aug 2018 - Sep 2018
    Murcia Y Alrededores, España
    Handling, analysing and interpreting clinical samples (urine, blood, faeces, sputum etc.), always under the supervision of physicians.
  • Department Of Human Anatomy And Psychobiology Of The University Of Murcia
    Student Internship
    Department Of Human Anatomy And Psychobiology Of The University Of Murcia Jun 2018 - Jul 2018
    Murcia Y Alrededores, España
    Knowing the main lines of research, cooperate with my tutor in the search of bibliography. Performing the usual techniques and methods in the Department: In Situ Hybridization in developing mouse brain to study the expression of several axon-guidance molecules.

Aarón Gallego Crespo Education Details

Frequently Asked Questions about Aarón Gallego Crespo

What company does Aarón Gallego Crespo work for?

Aarón Gallego Crespo works for University Medical Center Mainz

What is Aarón Gallego Crespo's role at the current company?

Aarón Gallego Crespo's current role is PhD student in Bioinformatics | Computational Biology | Cancer Omics.

What schools did Aarón Gallego Crespo attend?

Aarón Gallego Crespo attended Johannes Gutenberg University Mainz, Universitat Oberta De Catalunya, Universidad De Granada, Universidad De Murcia.

Who are Aarón Gallego Crespo's colleagues?

Aarón Gallego Crespo's colleagues are Andrea Kronfeld, Florian König, Claudia Simon Sánchez, Eva Bettina Kirr, Olaf Schäfer, Helena Dieterle, Dr. Alejandro Ceron-Noriega.

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