As a Senior Research Fellow at Nanyang Technological University (NTU) and an Advisor at Singzyme, I am driven by a passion for biochemistry and a commitment to advancing biomedical science. My journey in this field has been marked by pioneering research, innovative solutions, and a relentless pursuit of excellence.At NTU, I lead teams of researchers in groundbreaking studies focused on protein ligases, contributing significantly to the understanding and engineering of these critical enzymes. My work has resulted in over 26 high-impact scientific publications and multiple patents, particularly in the realm of antimicrobial resistance. This research not only pushes the boundaries of biomedical science but also holds the potential to address some of the most pressing health challenges of our time.In my role as an Advisor at Singzyme, I leverage my expertise in enzyme engineering to guide strategic decisions and foster innovation. As a member of the founding team and main co-inventor of our core technology, I have been instrumental in drafting the initial business plan, securing successful seed investment, and managing key relationships for technology transfer. Our collective efforts at Singzyme are a testament to our shared commitment to biotechnological solutions that address complex health challenges.My academic background includes a Research Doctorate in Biochemistry and Structural Biology from Paris-Sud University and a Master's degree in Life Science-Proteins Engineering from Université de Lorraine. These formative years equipped me with a robust foundation in biochemistry, molecular biology, and structural biology, which I have continuously built upon throughout my career.My top skills include leadership, fundraising, and scholarly research, all of which have been critical to my success in both academic and entrepreneurial settings.Looking ahead, I am excited to continue exploring the frontiers of biochemistry and biotechnology, driving innovation, and contributing to the development of solutions that can make a tangible difference in global health. If you share a passion for biochemistry, biotechnology, or are interested in potential collaborations, I would love to connect and explore how we can work together to advance this vital field.
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Chief Technology OfficerSingzymeSingapore
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AdvisorSingzyme Oct 2022 - PresentSingapore, SingaporeActing Chief Executive Officer• Member of the founding team as main co-inventor of the core technology• Drafted the initial Business Plan• Helped in fundraising efforts, presenting the company and BP to investors.Successful seed investment raised.• Managed daily operations for Singzyme• Managed relation with CDMO for technology Transfer• Managed relation with clients and prospects
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Senior Research FellowNanyang Technological University, Singapore Jul 2020 - PresentSingapourNanyang Technological University • Lead teams of researchers and completed independent research into Protein Ligases mechanism study and engineering.• Authored over 10 scientific papers for publishing in high impact factor peer-reviewed journals.• Authored 2 Patents• Secured research grants and completed studies in Antimicrobial Resistance projects. -
Research FellowNanyang Technological University Singapore Oct 2015 - Jun 2020Singapore• Developed unique research into Structural Virology.• Performed scientific research on multiple projects including Zika and Dengue Virus studies, Malaria.• Supported and supervised 2 post-doctoral researchers as well as 3 Ph.D. students.• Published over 10 research articles in top-tier research journals.
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Principal ScientistEpitoire May 2020 - Dec 2020Singapour• Supervised 5 junior technicians and 2 post-Doc research scientists.• Collected samples and carried out fieldwork.• Performed research into study topics to increase knowledge and to provide valuable contributions.
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Ph.D StudentInstitute For Integrative Biology Of The Cell (I2Bc) Oct 2012 - Sep 2015Gif Sur Yvette, FranceMy thesis is about the study of structure-function relationships of a periplasmic protein of Agrobacterium tumefaciens involved in the virulence of this pathogen.My job is to combine biological approaches (bacterial cultures, in vivo virulence tests), biochemical (expression, production and purification of recombinant proteins, enzymology, enzyme mechanisms, enzyme and protein assays, fluorescence techniques, microcalorimetry) and Biophysics (Crystallography, X-Ray diffraction, Macromolecural Structure resolution ).
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Study Of The Enzymatic Mechanism Of 3Mst, A Sulfurtransferase From E. ColiImopa, Umr 7365 Cnrs-Lorraine University Jan 2012 - Jun 2012Lorraine-University, Vandoeuvre Les Nancy, FranceDuring this 6 month internship under the supervision of Pr. Sandrine BOSCHI-MULLER, I determined the mechanism by which the 3MST from E. coli transfers a sulfur atom from 3mercaptopyruvate in order to produce H2S. I combined the kinetics parameters determination (Enzymatic assays) to the quantification of the products (HPLC, TLC) and the biophysical characterization of the reactionary intermediates (Mass Spectrometry).
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Masters StudentUniversité Henri Poincaré, Nancy 1 Sep 2009 - Jun 2012Université De LorraineMaster 2 Proteins and Enzymes Ingeneering
Abbas Sahili Education Details
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Biochemistry And Structural Biology -
Very Good -
Biochemisty, Molecular Biology
Frequently Asked Questions about Abbas Sahili
What company does Abbas Sahili work for?
Abbas Sahili works for Singzyme
What is Abbas Sahili's role at the current company?
Abbas Sahili's current role is Chief Technology Officer.
What schools did Abbas Sahili attend?
Abbas Sahili attended Paris-Sud University (Paris Xi), Universite De Lorraine, Universite De Lorraine.
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