Abhinav Gupta Email and Phone Number
Abhinav Gupta work email
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Abhinav Gupta personal email
I am an innovative early-stage discovery Senior Associate Scientist with expertise in molecular biology, protein science and novel platform development. My colleagues value me for being a data driven problem solver with a collaborative work style and being skilled in cell culture, protein engineering, and biological assay. My focus areas are molecular biology, cell culture, protein engineering, and biology assay.
Zag Bio
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Zag BioBoston, Ma, Us
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Senior Associate ScientistZag Bio Aug 2023 - PresentCambridge, Massachusetts, Us
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Associate ScientistXilio Therapeutics, Inc. May 2022 - Jun 2023Waltham, Massachusetts, UsTo enhance Xilio's pipeline, designed and developed a unique platform to develop biotherapeutic molecules with universal cleavage site. Also, devised a high throughput discovery workflow to screen hundreds of VHH proteins from phage display discovery campaign to identifying masks with enhanced masking properties.• Successfully generated hundreds of Fc fused cytokine with VHH or ScFv masks that has enzymatic cleavage properties by Protein Engineering and Molecular Biology techniques.• Screened >100 masked and un-masked Fc fused cytokine proteins for expression and purified them using high-throughput techniques like TECAN and Kingfisher. -
Senior Associate ScientistCompass Therapeutics Inc. Jul 2021 - May 2022Boston, Ma, Us• Generated bispecific molecules with ScFv and Fabs by utilizing protein engineering techniques like knobs/holes and electrostatic mutations • Produced grams of material by transient transfection of Expi293 HEK cell line and purified them by ProA and SCX purification techniques on AKTA Avant and Pure. • Characterized the expressed protein using biochemical analysis techniques example SDS-PAGE, Analytical Size Exclusion chromatography (SEC).• Collaborated with Senior Scientist on Phage display technology for a naive antibody discovery campaign. • Executed functional and reporter assays using Tcell and cd3 cd28 labeled dyna beads for a novel autoimmune agonist project.• Worked with Genewiz and IDT to generate plasmid and gblock/primers, respectively.• Helped manage the project timelines, and presented data in team meetings -
Senior Research AssociateMomenta Pharmaceuticals Jul 2015 - May 2021Cambridge, Massachusetts, Us• Engineered Antibody like molecule to increase the Fc effector function using protein engineering and Molecular Biology techniques like PCR mutagenesis and Gibson cloning. • Transiently expressed recombinant protein at various scales and purified them using AKTA• Generated stable Expi HEK293 and Expi CHO cell line and characterized them using FACs•Performed Biophysical and biochemical analysis of the protein. -
Research Assistant, Department Of Pharmaceutical ScienceNortheastern University Aug 2014 - Jul 2015Boston, Ma, Us• Maintained T cells, DC cells, MCF7 cells by performing Mammalian Cell Culture techniques• Performed Droplet Microfluidics Assays to evaluate the effect of different drug candidates on MCF7 resistant and sensitive breast cancer cell lines in alginate-calcium droplets • Implemented microfluidics bioassays to investigate the formation of immunological synapses by studying the interaction between T Cells, Dendritic Cells and Tumor Cells • Performed Live Dead Assay techniques to study viability of tumor cells • Involved in microfluidics devices fabrication• Executed ELISA to study the sustained release of proteins in different material -
Research Assistant, Department Of PathologyTufts University May 2014 - Aug 2014Medford, Massachusetts, Us• Performed animal handling and harvested different mice organ for experimental purpose • Executed Western Blot on tissue lysate to study cFLIP contributes in MSM/Ms mice T cell’s deciding to undergo apoptosis or necroptosis when stimulated with various agonists in vitro • Estimated protein level in different organ of mice by Bradford Assay• Determine the homogeneity and heterogeneity in different generation of mice by performing PCR • Studied histopathology samples to analyze the contribution of the anti-apoptotic protein cFLIP in MSM/Ms resistance to liver pathology in vivo
Abhinav Gupta Skills
Abhinav Gupta Education Details
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Northeastern UniversityBiotechnology -
Amity UniversityBiotechnology
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Harvard Extension School
Frequently Asked Questions about Abhinav Gupta
What company does Abhinav Gupta work for?
Abhinav Gupta works for Zag Bio
What is Abhinav Gupta's role at the current company?
Abhinav Gupta's current role is Senior Associate Scientist | Molecular Biologist | Protein Engineering, Expression & Purification | Assay Development.
What is Abhinav Gupta's email address?
Abhinav Gupta's email address is ag****@****rma.com
What schools did Abhinav Gupta attend?
Abhinav Gupta attended Northeastern University, Amity University, Harvard Extension School.
What are some of Abhinav Gupta's interests?
Abhinav Gupta has interest in Environment.
What skills is Abhinav Gupta known for?
Abhinav Gupta has skills like Biotechnology, Research, Microsoft Office, Microsoft Excel, Powerpoint, Cell Culture, Microsoft Word, Western Blotting, Elisa, Pcr, Assay Development, Immunology.
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