Nirupama Lal Email & Phone Number

Bangalore, Karnataka, India.

• Established required laboratory infrastructure
• Served as Head of R&D for the design and development of translational research in the field of autoimmune disease like psoriasis and eczema, obesity and diabetes.
• Played a key role in the designing project for the following molecules that are under the process of execution:
• Agonist for Peroxisome Proliferator-activated receptors (PPAR) gamma,The antagonist for Dipeptidyl peptidase IV (DPP4/CD26), Farnesyl pyrophosphate synthetase (FPPS), platelet P2Y12 receptors, Phosphodiesterase 4.
• Purification of Cell permeable peptides (CPP) and Antimicrobial peptides (AMP) from medicinal plants.
• Assisted lab experiments in troubleshooting to ensure the proper functioning of the protocols.

NCR, Delhi, India

• Helped in the establishment of Section-8 Company.
• Created the organization's mission and vision statements that would be utilized by all employees.
• Developed and maintained positive relationships with employees.
• Assisted with the creation of the marketing strategy and advertising initiatives that were used to promote the company to the public.
• Organized discussion group (8+ members) focused to support the entrepreneurial talents in researchers or scientists towards the commercialization of their scientific aspirations.

Kanpur, UP.

• Worked directly with the department to achieve its goal.
• Took four lectures per week during semester.
• Areas taught: Cell biology, Microbiology, Ecology and Bioinformatics to M.Sc. postgraduate students.
• Achieved the departmental objective by successful completion of the courses.

Hyderabad, India

• Awarded research grant and completed studies funded by academic groups. Independently designed and executed the project.
• Established mitochondrial research lab in the institute.
• Successful completion of the self-written project on 'Characterization of mitochondria associated senescence mechanism in obese mutant rat' through ICMR, New Delhi funding.
• Compared the mitochondrial swelling in female WNIN/Obese (O) rats at different ages to that of WNIN-parental (W) and WNIN/Ob lean (L) rats as controls along with physical and biochemical parameters.
• The obese rats were fed normal rat chow ad libitum and portrayed features of obesity such as higher body weight with hyperinsulinemia, which is similar to the preclinical /clinical features of obesity induced type 2.
• The whole body dual energy X-ray absorptiometry (DXA) and biochemical analysis of fasting plasma were performed.

Hyderabad, Telangana, India

• Designed experiments to study genetics and epigenetics of obesogenecity.
• Provided research support, case writing and data analysis, managed case submission process, edited, redrafted, and commented on working papers.
• Drafted successful project proposal for funding from ICMR, New Delhi, India for Postdoctoral fellowship.
• Co-authored 1 review on 'Genetics and epigenetic approach to Human Obesity'.
• Managed creative projects from concept to completion.
• Trained junior members of research team regarding molecular biology and troubleshooting of the experiments.

Hyderabad, Telangana, India

• Initiated the isolation and characterization of adult cardiac stem cell from perfused mice heart.
• Set up equipment, organized inventory and maintained facilities.
• Produced actionable information that improved the perfusion experiments.
• Provided methodologies for the isolation of mono-nuclear cardiomyocytes.

Columbus, Ohio, USA

• Established methods to detect and regulate mitochondrial programmed cell death.
• Demonstrated active participation of complex-III of ETC in apoptosis.
• Presented poster at 2008 VIIth Annual OSUMC Research Day on 'Association of complex-III of electron transport chain in apoptosis'.
• Studied the 'Differential effects of non-steroidal anti-inflammatory drugs on mitochondrial dysfunction during oxidative stress' and got first author publication.
• Produced and managed extensive data for fatty acid analysis under different conditions and provided recommendations to rescue the damage due to ischemic reperfusion in vitro.
• Coordinated with other labs for aid in project completion.

Columbus, Ohio, USA

• Standardized protocols and conditions for the study of mitochondrial apoptosis.
• Trained in studying mitochondrial biology and physiology at molecular level, isolation of mitochondria from heart, liver, brain and skeletal muscles, its permeability transition study through spectrophotometer, Ca2+.
• Obtained online certificate for Institutional Animal Care and Use for the research purpose.
• Supported Principal Investigator (PI) with daily research functions.
• Produced data analysis reports for senior team members and PI.
• Researched and updated all required materials needed for the lab.

UP, India

During my Ph.D. I used various DNA Fingerprinting techniques to study diversity among various species of aromatic grasses. I had been trained in various molecular biology techniques like from DNA/RNA isolation, qPCR, cloning, sequencing, hybridization, primer designing, molecular marker development etc. In brief I used to isolate DNA from different.

Uttarakhand, India

• Demonstrated a continued commitment to postgraduate teaching through full participation in the college community.
• Taught Biophysics, Biochemistry, Molecular biology, Microbiology, Immunology in Biotechnology and Biomedical Sciences courses
• Developed courses in line with the curriculum requirements of the Biotechnology Department.
• Organized seminars and conferences related to molecular biology, biochemistry, microbiology, immunology etc. to create awareness in the students for the perspective research areas.
• Established molecular biology and tissue culture lab and supervised and evaluated students' laboratory work.
• Established departmental library for referencing the literature.

Lucknow, UP, India

• Identified species-specific molecular markers in both genera of Cymbopogon and Vetiveria zizanioides
• Characterized both the genomes through RAPD and AFLP
• Identified novel molecular marker showing sequence similarity with ndhD of evolutionary significance
• Sequenced the marker fragment and submitted to Genebank as gbIEU871430.1
• Presented results at departmental seminars and retreats to audiences of 20+ people
• Generated high quality, professional papers for submission to scientific publications.

Lucknow, UP, India

• Learned and developed molecular biology skills through standardization of the techniques
• Worked on molecular characterization of the medicinal and aromatic grasses.
• Maintained high levels of confidentiality to ensure data quality and project research.
• Performed various scientific duties on a daily basis, including autoclave, DNA isolation, PCR, media preparation, competent cell preparation, cloning and paper writing and presentation.
• Developed and implemented laboratory protocols and modified when needed.

Lucknow, Uttar Pradesh, India

• Learned molecular biology skills like PCR, RAPD, gel electrophoresis etc., data compilation and literature search
• Learned paper writing and presentations at seminars and conferences
• Participated in organization of seminars and conferences/workshops
• Learned molecular characterization of the medicinal and aromatic grasses.
• Assisted seniors and principal investigators in their research project.

Ph.D., Lifesciences, Awarded

Activities and Societies: 1. National conference on Plant Biotechnology: Towards Strategic Agriculture and Drug Development, Lucknow.

M.Sc., Lifesciences, First Division

Activities and Societies: • 2nd Position in the University. • Successfully completed the coursework in in Molecular biology, Biochemistry.

B. Sc., Zoology, Botany & Chemistry, First Division

Activities and Societies: Done practicals and project work related to course curriculum. • Coursework in Zoology, Botany and Chemistry. •.