Aaron Edwards Email & Phone Number

Cambridge, Ma, Us

Danville, Ky, Us

Boston, Ma, Us

As a Blavatnik Fellow in Life Science Entrepreneurship at Harvard Business School, I am leveraging mentorship from biotech and biomedical leaders to advance our work at KiraGen Bio. This 12-month fellowship provides a unique opportunity to develop leadership skills and collaborate with experts, shaping the future of science and innovation.

Boston, Massachusetts, Us

As a Henri Termeer Fellow, I am part of a values-driven leadership program designed for first-time CEOs and entrepreneurs in the biopharmaceutical industry. The program focuses on fostering inclusivity, providing executive coaching, mentoring, and skill development to empower a diverse group of current and future leaders. Through networking opportunities and peer-to-peer learning, the fellowship strengthens leadership capabilities while addressing underrepresentation at the executive level.

Boston, Massachusetts, Us

Indianapolis, Indiana, Us

Us

Boston, Us

Nucleate is a free and collaborative student-run organization that facilitates the formation of pioneering life sciences companies.

Boston, Ma, Us

San Rafael, Ca, Us

Los Angeles, Ca, Us

Cambridge, Massachusetts, Us

Cambridge, Massachusetts, Us

Cambridge, Massachusetts, Us

Working in our New Opportunities group, exploring and vetting applications of current and novel base editing technologies in the context of immune cell-based therapies.

Somerville, Massachusetts, Us

Early research and discovery with a primary focus on gene editing for immunotherapy products. Continued efforts at gene editing platform and process improvements while evaluating next generation technology to fill future pipeline.

Somerville, Massachusetts, Us

Exploratory research and discovery, primarily in the context of gene editing applications of our megaTAL platform. Focused on evaluation and integration of new cell and gene therapy technologies to improve platforms across the company while also leveraging our resource infrastructure to investigate potential new indications for our long-term product pipeline.

Basel, Baselstadt, Ch

Mentors: Dr. Dong Yu, Dr. Christie BellProject Overview: The development of nucleic acid-based vectors for next generation vaccine strategies; part of the DARPA:ADEPT program.● Executed duties in coordination with lab manager to maintain an optimal working environment.● Optimized constructs utilizing Novartis’ SAM® technology.● Optimized construct potency assays with BHK-21 cells.● Generated and performed quality control analyses on large batches of SAM® for numerous animal studies.● Evaluated strategies for enhancing translation of vector-encoded proteins.● Developed and optimized a quantification assay to measure levels of protein production off of enhanced nucleic acid constructs.

Cambridge, Ma, Us

Mentors: Dr. Galit Alter, Dr. Todd SuscovichProject Overview:The development of a nucleic acid - based approach to rapidly provide transient immunity to pathogens.Thesis Work: Producing Functionally Enhanced Monoclonal Antibodies in vivo via Gene Therapy•Designed, produced, purified, functionally and structurally validated glyco-engineered monoclonal antibodies. •Generated and validated cell lines stably expressing transgenes.•Isolated and stimulated primary lymphocytes to evaluate antibody expression levels.•Designed, optimized, cloned, and validated various nucleic acid constructs through molecular cloning techniques including Gibson assembly and in vitro transcription.•Developed and optimized numerous strategies to deliver nucleic acids to multiple immortalized cell lines and primary cells using nucleofection/electroporation techniques, lipid-based delivery, and microfluidic chip systems (CellSqueeze Technolog- SQZ).

Nashville, Tennessee, Us

Mentors: Dr. Eva Harth, Ghazal HaririProject Overview: Sequential Targeted Delivery of Paclitaxel and Camptothecin Using a Cross-Linked “Nanosponge” Network for Lung Cancer Chemotherapy. (See Publications)•Systematically prepared a series of targeted, biodegradable nanoparticles in a variety of distinct nanoscopic size dimensions using an intermolecular chain cross-linking reaction. •Functionalized nanoparticles with fluorescent dyes, molecular signals, and various chemotherapeutics for use as a cancer drug delivery system.•Utilized the chorioallantoic membrane (CAM) model as a preclinical evaluation tool, testing the targeting efficiency of the variously sized carriers.•Determined efficacy of the targeted particles in single and combination therapies with paclitaxel and camptothecin chemotherapeutics in murine tumor growth delay studies.

Tampa, Fl, Us

Mentor: Dr. Jin Q. ChengProject Overview: Connecting deregulation of IKBKE to tumor progression, poor prognosis, and cisplatin resistance in ovarian cancer.•Measured IKBKE expression in human ovarian cancer samples.•Correlated expression levels with clinical outcomes.

Tampa, Fl, Us

Mentors: Dr. Ed Seto, Dr. Zhigang YuanProject Overview: Ascertaining the role ARS2 plays in modulating cell fates as a negative regulator of SIRT1-Foxo1 pathway.•Confirmed protein-protein interaction between ARS2 and SIRT1 in multiple cancer cell lines. •Evaluated downstream effects of chemically regulating either protein’s expression levels.

Bowling Green, Ky, Us

Mentors: Dr. Jeffrey Marcus, Tia Hughes Project Overview: A Simulation Study of Mutations in the Genetic Regulatory Hierarchy for Butterfly Eyespot Focus Determination.•Collected Lepidoptera field samples.•Sequenced and analyzed DNA from samples.•Created a Lepidoptera phylogenetic tree from compiled data.

Ms/Mba Biotechnology: Life Sciences, Biotechnology And Business

Ms/Mba Biotechnology: Life Sciences

Master Of Science (Msc), Medical Sciences (Immunology/Virology)

Bachelor Of Science (Bs), Biology