Afshin Beheshti Email and Phone Number
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My research is dedicated to exploring the intricate interplay of circulating miRNAs and mitochondria in the context of various diseases. I am particularly focused on unraveling how circulating miRNAs can serve as valuable biomarkers and potential therapeutic agents in combatting conditions such as cancer, COVID-19, long COVID, and the physiological effects of space biology.Currently, I am actively engaged in multiple projects, under my own at the Blue Marble Space Institute of Science at NASA Ames Research Center. These projects aim to identify countermeasures and enhance our biological understanding to mitigate the adverse effects of the space environment on living organisms. Simultaneously, I am involved in diverse initiatives addressing the multifaceted aspects of COVID-19 and long COVID. Furthermore, I am committed to advancing our knowledge of cancer biology, specifically exploring the application of miRNAs as both biomarkers and potential therapeutic interventions. Lastly, I involved in developing a personal AI assistant for the world to use!My expertise spans bioinformatics and systems biology, where I have successfully devised innovative experimental approaches to propel my research forward. Additionally, I possess extensive proficiency in imaging techniques, encompassing confocal, fluorescent, and light microscopy. My contributions extend to the development of novel imaging methodologies for live cell imaging and comprehensive image analysis.Driven by a passion for unconventional thinking, my overarching goal is to continually push the boundaries of conventional ideas and implement creative solutions. This approach is crucial in providing a more profound understanding of space biology and cancer development.
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Director Of Center For Space BiomedicineUniversity Of PittsburghBoston, Ma, Us
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Director Of Space Biomedicine ProgramUniversity Of Pittsburgh Sep 2024 - PresentPittsburgh, Pa, UsI will be starting a space biomedicine program at Pitt and looking for collaborators to partner with us.
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Associate Director Of Mcgowan Institute For Regenerative MedicineUniversity Of Pittsburgh Sep 2024 - PresentPittsburgh, Pa, UsContinue pushing my research forward.
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Professor Of Surgery And Computational And Systems BiologyUniversity Of Pittsburgh Sep 2024 - PresentPittsburgh, Pa, UsContinue my ongoing research at University of Pittsburgh
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PresidentKwaai Aug 2023 - PresentLos Angeles, UsStarting a grassroots AI initiative to better humanity. The mastermind behind this great initiative is Reza Rassool.We’re looking for people to join and volunteer their time to help us push this initiative forward. -
Scientific AdvisorUrsa Bio Feb 2022 - PresentScientific Advisor for Ursa Bio. -
PresidentCovid-19 International Research Team Mar 2020 - PresentI'm lead of a non-profit called COVID-19 International Research Team (COV-IRT, www.cov-irt.org), comprising of scientists driving research into COVID-19. This interdisciplinary group from over 80 institutions worldwide is coordinating projects focused specifically on SARS-CoV-2, including determining heterogeneity of the viral genome sequence, analyzing host response to COVID-19 disease, characterizing potential co-infections, and identifying potential therapeutic targets for preclinical and clinical development.PurposeThe purpose of the COVID-19 International Research Team is to rapidly improve our understanding of SARS-CoV-2 and develop a vaccine and/or therapeutics against SARS-CoV-2. We have formed a multidisciplinary team of researchers and will use a large consortium open science model to combine data, expertise, and labor to accelerate the process of finding a vaccine and/or therapeutics and provide tools for the public for COVID-19.Goals:-Enhance public datasets to reveal host infection dynamics for SARS-CoV-2 to improve medical treatment options for COVID-19 patients.-Determine and design optimal targets for therapeutics against SARS-CoV-2.-Create new drug delivery systems based on targets.-Test newly developed therapeutics in both in vitro and in vivo SARS-CoV-2 models.-Apply for human clinical trials.-Establish a multi-institutional collaborative team for rapid response for current and future pandemics.-Provide free tools and resources for the public -
Visiting ResearcherBroad Institute Of Mit And Harvard Apr 2019 - PresentCambridge, Ma, UsI obtained a Visiting Researcher appointment at Broad Institute. This will involve my current work under my own funded projects which I'm currently conducting at NASA. -
Bioinformatician And Principal InvestigatorNasa Ames Research Center Apr 2017 - Sep 2024Moffett Field, California, UsI work on several projects related to funding I have acquired that covers different subject which include: miRNA changes related to the space environment, mitochondrial changes due to the space environment, COVID-19 impact on human health, utilizing machine learning techniques to determine optimal countermeasure/therapeutics for space biology and cancer work, and impact of high altitude flight on central nervous system issues.In addition I am leading the GeneLab Analysis Working Group on Multi-Omics/Systems Biology to help develop the best tools and pipelines to implement on GeneLab. -
Scientific Advisory BoardYuri Jul 2022 - Jul 2024Meckenbeuren, Baden-Württemberg, DeServing on the Scientific Advisory Board of Yuri. -
Adjunct Assistant ProfessorRutgers Robert Wood Johnson Medical School Jun 2018 - Jul 2020New Brunswick, Nj , UsThis appointment will allow my work to continue on cancer research while I still work at NASA -
Assistant ProfessorTufts Medical Center Oct 2014 - Nov 2017Boston, Ma, UsProjects include studying the impact of microRNAs on cancer; aging effects with and without HZE and low LET irradiation on tumorigenesis; investigating effects of drugs on lymphomas and leukemia from clinical samples and in vitro experiments. -
Director Of The Microscopy CoreSt. Elizabeth'S Medical Center Jun 2008 - Sep 2014• Overseeing the microscope core facility which includes maintenance, setup, and repair of equipment for the following types of microscopes: Confocal Microscope, Epi-Fluorescent Microscopes (with and without environmental chamber for live cell imaging), and Light Microscopes.• Develop and implement quantitative image analysis techniques.• Conduct training on all microscopes and analysis techniques to the scientific staff.• Council faculty and scientific staff on best experimental setup for different microscopes at the facility.
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Assistant Professor / Associate InvestigatorTufts University School Of Medicine / St. Elizabeth'S Medical Center Feb 2006 - Sep 2014Freiburg I. Br. , DeProjects include studying aging effects with and without HZE and low LET irradiation on tumorigenesis; the effects of DNA double strand breaks (DSBs) in tumors and the influence on the neighboring stromal cells; cell-cell interaction and the effects of cell fusion on carcinogenesis; cancer stem cells and the developmental process during beginning stages of cancer; radiation resistance of cancer stem cells; and differential x-ray tomography imaging on tumors from both clinical samples and murine samples. Accomplishments included:• Performed comprehensive statistical data analysis with multiple technology platforms including: Bioinformatics and Gene Arrays, Flow Cytometry, qPCR, PCR, and ELISA.• Systems biology approach that incorporated in vivo and in vitro experiments (with extensive bioinformatics works) with computer modeling for predictions of the system being studied.• Managing a portfolio of projects from study design and conception to execution, milestone progress tracking and data quality review.• Prepared and edited manuscripts for submission to scientific journals. • Published articles in peer-reviewed journals: Analysis and interpretation of experimental data, development of logical structure, preparation of figures, writing and editing of manuscripts.• Wrote abstracts and developed oral and poster presentations for international conferences.• Apply new imaging techniques to understanding tumorigenesis. • Conducted gene array analysis and bioinformatics on different studies dealing with cancer progression.• Successfully developed study protocols for the Institutional Review Board (IRB) to conduct experiments using clinical samples.• Successfully designed experiments, wrote research proposals, and obtained approval from an international laboratory (Paul Scherrer Institut in Switzerland) to conduct differential x-ray tomography imaging experiments.• Mentored graduate students, undergraduates, and medical research fellows. -
ConsultantNanobiosym Dec 2005 - Feb 2006Cambridge, Ma, UsI was successful in troubleshooting on various experiments which needed to be completed by a deadline. Provided useful tips and advice to improve their experiments in speed, quality, and purity. -
Postdoctoral FellowThe Forsyth Institute Jan 2003 - Feb 2006Cambridge, Ma, UsThe project was to sequence, assemble, and annotate the genome of uncultivable oral bacterium, phylotype TM7. This will be one of the first genomes of an “uncultivable” bacterium, from “uncultivable” phylum to be sequenced. Accomplishments included:• Demonstrated a new way to grow uncultivable oral bacterium & enrichment of uncultivable spirochetes.• Successfully modified Fosmid cloning techniques to work with minimal amount of DNA.• Successfully screened Fosmid clones for TM7 using colony hybridization.• Successfully utilized techniques such as: sequencing, assembling, and annotation of the genome of an uncultivable oral. bacterium, pulsed field gel electrophoresis, isolating DNA from bacteria, real time PCR for quantitative and qualitative analysis, and Fluorescent in situ Hybridization (FISH) with a confocal microscope. -
Research Assistant/Graduate StudentFlorida State University Aug 1997 - Dec 2002Tallahassee, Fl, UsDuring my graduate work in biophysics, I was able to develop and expand on an equation that universally described the mobility of DNA through different gels using various electrophoresis techniques. Accomplishments included:• Developed a new exponential function describing the length dependence on mobility of DNA through gel networks.• Designed new apparatus for electrophoresis experiment.• Investigated a video imaging method using a charged couple device (CCD) camera to image the diffusion of DNA bands in agarose gels.• Investigated 2D electrophoresis techniques on proteins in polyacrylamide gels.• Participated in the Surface structure study of polyacrylamide gels by atomic force microscopy (AFM).• Successfully utilized techniques such as: performing extensive analysis on the mobility of DNA as a function of length using a variety of fitting programs, pulsed field electrophoresis experiments on double stranded DNA in Pluronic F127 gels, electrophoresis experiments on double stranded DNA through various gels, and Pluronic gels.• Teaching introductory Astronomy & Physics Laboratory courses. -
Teaching AssistantFlorida State University Aug 1997 - Aug 2002Tallahassee, Fl, Us• Introductory Astronomy Laboratory at the undergraduate level. Monitored performance and graded reports• College Physics Laboratory at the undergraduate level. Monitored performance and graded reports
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Research Internship3M Jan 1997 - Aug 1997St Paul, Mn, UsPerformed mathematical modeling and numerical solutions, studied the current flow and the electric field in flexchips for inkjet printers. -
Research AssistantUniversity Of Minnesota Jun 1994 - Jan 1997Minneapolis And St. Paul, Minnesota, UsAs an undergraduate I participated in a number of High Energy Physics experiments. The work included:• Participated in research and development on the Main Injector Neutrino Oscillation Search (MINOS).• Participated in research and development on the Compact Muon Solenoid (CMS) experiment.• Assisted in constructing the g-2 experiment at Brookhaven National Laboratories.• Conducted studies to identify single proton decay at the Soudan II detector.• Gained extensive knowledge in electronics and computer programming, data interpretation and analysis.• Developed a multi-media system on computers for future undergraduate physics courses. -
Research AssistantUniversity Of Illinois Jun 1996 - Aug 1996Urbana-Champaign, Chicago, And Springfield, Il, UsDesigned a GPS (global positioning system) based global time-stamping system. Designed a software interface by programming in C++ and data interpretation and analysis
Afshin Beheshti Skills
Afshin Beheshti Education Details
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Florida State UniversityBiophysics -
University Of MinnesotaPhysics
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Apple Valley Senior High School
Frequently Asked Questions about Afshin Beheshti
What company does Afshin Beheshti work for?
Afshin Beheshti works for University Of Pittsburgh
What is Afshin Beheshti's role at the current company?
Afshin Beheshti's current role is Director of Center for Space Biomedicine.
What is Afshin Beheshti's email address?
Afshin Beheshti's email address is af****@****fts.edu
What is Afshin Beheshti's direct phone number?
Afshin Beheshti's direct phone number is +161763*****
What schools did Afshin Beheshti attend?
Afshin Beheshti attended Florida State University, University Of Minnesota, Apple Valley Senior High School.
What are some of Afshin Beheshti's interests?
Afshin Beheshti has interest in Reading Books, Programming, Cooking, Biotechnology, Playing Music, Biking, Digital Photography, Microscopy, Researching And Understanding Cancer.
What skills is Afshin Beheshti known for?
Afshin Beheshti has skills like Microscopy, Cell, Confocal Microscopy, Pcr, Bioinformatics, Fluorescence Microscopy, Cancer, Flow Cytometry, In Vitro, Cell Biology, Cell Culture, Molecular Biology.
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