Organism Engineer 3
CurrentDesigning and engineering yeast strains to optimize production of high-value compounds and bio-based materials
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Alexis Tomaszewski is listed as Organism Engineer 3 at Ginkgo Bioworks, Inc., a with 445 employees, based in Worcester, Massachusetts, United States. AeroLeads shows a matched LinkedIn profile for Alexis Tomaszewski.
Alexis Tomaszewski previously worked as PHD Researcher at Johns Hopkins Medicine and Research Fellow at University Of Massachusetts Amherst. Alexis Tomaszewski holds Doctor Of Philosophy - Phd, Biochemistry, Cellular, And Molecular Biology from The Johns Hopkins University School Of Medicine.
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I am an enthusiastic cellular and molecular biologist with over a decade of experience in discovery biology, specializing in high-throughput genetic screens and advanced molecular techniques. My journey has been driven by a passion for unraveling the complexities of cellular mechanisms and leveraging cutting-edge technologies to push the boundaries of scientific knowledge.During my doctoral research, I devised a groundbreaking high-throughput genetic screen utilizing a liquid handler and fluoresence microscopy to investigate factors influencing the dissolution of protein aggregates implicated in neurodegenerative diseases. This endeavor not only uncovered novel mechanisms and regulators shedding light on potential therapeutic targets for neurodegenerative diseases, but also underscored my proficiency in molecular editing and innovative cell-based assay development to characterize cellular phenotypes. Collaboration is at the heart of my approach to research. I have actively engaged in multidisciplinary projects, including a flow cytometry-based genome-wide screen aimed at elucidating regulators of cytosolic protein homeostasis, resulting in the identification of key metabolic factors regulating proteostasis in yeast and mammalian systems.Beyond the bench, I am deeply committed to fostering collaboration and mentorship. I have mentored junior scientists, facilitated research symposia, and actively contributed to initiatives promoting diversity and inclusion in academia.Looking ahead, I am eager to apply my expertise in cellular and molecular biology to contribute to next-generation medicines. With a track record of innovation, collaboration, and leadership, I am prepared to tackle new challenges and make meaningful contributions to the scientific community.
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Boston, Massachusetts, United States
Designing and engineering yeast strains to optimize production of high-value compounds and bio-based materials
Baltimore, Maryland, United States
Initiated and performed protein homeostasis research related to aging and neurodegeneration in the lab of Dr. Rong LiDiscovered novel molecular regulators of protein homeostasis through innovative genetic engineering and cellular assays, complemented by rigorous quantitative analysis at JHSOM with Rong Li, PhD •Developed a high-throughput genetic screen from library design and construction, high-throughput transformation with a liquid handler, high-content imaging through fluorescent microscopy, and comprehensive evaluation of cell-based phenotypic data for candidate investigation•Revealed a groundbreaking phase transition in protein aggregates during dissolution in vivo, unveiling critical chaperone domains involved in this process. Identified unconventional regulatory factors including RNAses and glycolytic enzymes, offering potential avenues for future therapeutic targets in aging and neurodegeneration•Collaborated on a team project to execute a genome wide screen to uncover regulators of cytosolic proteostasis through importing of misfolding proteins into the mitochondria, leading to the discovery of Snf1/AMPK as a protective factor for mitochondrial fitness in yeast and mammalian cells•Mentored and supervised junior scientists guiding research from experimental design, molecular biology experiments, and quantitative data analysis, with the creation of Standard Operating Procedures
Amherst, Massachusetts, United States
Investigated the underlying mechanisms behind dynein-mediated nuclear migration and microtubule stability in budding yeast utilizing various molecular genetics techniques and in vivo imaging
Amherst, Massachusetts, United States
Conducted plant cell biology research in the moss Physcomitrella patens and investigated mechanisms that drive polarized cell expansion utilizing RNAi for genetic analysis
United States
Researched breast cancer progression and metastasis in mammalian cell culture focusing on endosomal trafficking mutants that regulate the expression of intracellular signaling through RNAi analysis
Other employees you can reach at ginkgobioworks.com. View company contacts for 445 employees →
Ryan Harry
Colleague at Ginkgo Bioworks, Inc.Boston, Massachusetts, United States
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Syed Salman
Colleague at Ginkgo Bioworks, Inc.Bengaluru, Karnataka, India
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Emeline Dagorn
Colleague at Ginkgo Bioworks, Inc.Greater Paris Metropolitan Region, France
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David Zhou
Colleague at Ginkgo Bioworks, Inc.Greater Boston, United States
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Catherine Li
Colleague at Ginkgo Bioworks, Inc.United States
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Jingxuan Lexie Cui
Colleague at Ginkgo Bioworks, Inc.Greater Boston, United States
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Rebecca Katzman
Colleague at Ginkgo Bioworks, Inc.Cambridge, Massachusetts, United States
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Melody Keith
Colleague at Ginkgo Bioworks, Inc.Boston, Massachusetts, United States
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Kim Evernham
Colleague at Ginkgo Bioworks, Inc.Boston, Massachusetts, United States
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Diemmy Nguyen
Colleague at Ginkgo Bioworks, Inc.Greater Boston, United States
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Quick answers generated from the profile data available on this page.
Alexis Tomaszewski works for Ginkgo Bioworks, Inc..
Alexis Tomaszewski is listed as Organism Engineer 3 at Ginkgo Bioworks, Inc..
Alexis Tomaszewski is based in Worcester, Massachusetts, United States while working with Ginkgo Bioworks, Inc..
Alexis Tomaszewski has worked for Ginkgo Bioworks, Inc., Johns Hopkins Medicine, University Of Massachusetts Amherst, and Umass Medical School.
Alexis Tomaszewski's colleagues at Ginkgo Bioworks, Inc. include Ryan Harry, Syed Salman, Emeline Dagorn, David Zhou, and Catherine Li.
You can use AeroLeads to view verified contact signals for Alexis Tomaszewski at Ginkgo Bioworks, Inc., including work email, phone, and LinkedIn data when available.
Alexis Tomaszewski holds Doctor Of Philosophy - Phd, Biochemistry, Cellular, And Molecular Biology from The Johns Hopkins University School Of Medicine.
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