Andrew Woolley Email & Phone Number

Lawrence Township, Nj, Us

Responsible for the development of well-validated tissue-based research assays and their utilization for decisional biomarker support across numerous Immuno-Oncology programs at BMS.Leading spatial-analysis characterization of histology tissues using chromogenic immunohistochemistry (IHC), multiplex immunofluorescence (mIF), in situ hybridization (ISH), spatial transcriptomics (10x platforms), and digital pathology image analysis (HALO AI platform).SME managing the transfer of novel, in-house IHC assays and materials to CRO-partners in support of multiple early-stage clinical programs.

North Chicago, Illinois, Us

Driving the validation and execution of cutting-edge tissue-based assay technologies to inform drug discovery and translation in Oncology under the Precision Medicine organization at AbbVie.Leveraging AI-based digital pathology image analysis for cell segmentation, tissue classification, and cellular neighborhood clustering on whole-slide imaging data (IHC, ISH, IF, highplex-IF).Working closely with bioinformatics, genomics, and clinical program leads to generate predictive signatures for clinical trial biomarker decision making.

San Francisco, Ca, Us

Responsible for independent and team-based design, execution, and analysis of biological assays to support translation of pipeline projects and drug candidate selection with tissue-based and cell-based assays at a biopharma startup. From blood-flow assays up to preclinical animal studies, performed across a variety of indications from vascular diseases, oncology, CNS disorders & fibrosis. Work performed in-house, at microscopy facilities, and through supervising CRO partners. Responsibilities also included supporting all scientists in advanced histology, imaging, and image analysis needs, as well as managing pathology and microscopy equipment purchasing.

San Francisco, Ca, Us

Consultant supporting preclinical, translational research at Symic Bio and other Bay Area startups, including IHC and in vitro assay development.- Optimizing experimental & histological strategies to assess novel therapeutics- Performing advance microscopy, data analysis, etc., to generate and evaluate preclinical data- Designing and supervising surgery, tissue collection, and sample processing in animal models

Sydney, New South Wales (Nsw), Au

Postdoc with Bionic Vision Australia​ consortium, developing visual prosthesis technology. Led imaging projects to support clinical device translation under Scientia Prof. Nigel Lovell (School of Biomedical Engineering) and Prof. John Morley (School of Medicine). http://bionicvision.org.au/- Utilizing micro-CT and 9.4T MRI equipment to image 'bionic eye'​ implant within tissue.- Imaging physiology (two-photon microscopy) in retinal tissue and neural cultures.- Performing translation research using human cadaver and larger lab animal tissues.- Successful grant (Cooper Medical Research Foundation): gene therapy AAV imaging in retina.- Contributing Investigator on successful grant (NHMRC): microstimulation of retinal tissue.- Conceiving, assigning, and guiding projects in the Graduate School of Biomedical Engineering.

West Lafayette, In, Us

DARPA-funded Postdoc in SUBNETS program. Developed and utilized advanced histological imaging and 'cranial window'​ imaging methods to capture device integration data within brain tissue.- Discovered depth-dependent response of immune cells to brain implanted microdevices.- Published on PNS cells entering CNS around brain implants.- Integrated 'optical clearing'​ strategies into the histological processing of device-implanted brain tissue, allowing deeper imaging into tissue around implanted devices.- Paired 'cranial-window'​ imaging with brain-implanted microelectrode arrays, imaging transgenic biomarkers over time while recording physiology and electrical impedance.- Devised and validated a 'systemic labeling' strategy to allow simultaneous assessment of blood vessel reorganization and blood-brain-barrier permeability around brain implants in histology.

West Lafayette, In, Us

Improved our understanding of the brain-implanted microdevice integration in brain tissue. Informed the development of biomedical implants for treating diseases and disorders of the nervous system.- Developed innovative method (Device-Capture Histology) to reveal complex changes around brain implants across a variety of neural cell types (oligodendrocytes, microglia, astrocytes, neurons)- Achieved multidisciplinary expertise in aseptic surgery, laser-based microscopy, immunohistochemistry, neurobiology, immunology, and neural engineering.- Coordinated a small team to successfully integrate new research techniques into the lab.- Presented at Society for Neuroscience and other conferences (BMES, M&M, etc.).

West Lafayette, In, Us

Enjoyed teaching, consistently received high teacher ratings from students:- Biology of the Living Cell- Quantitative Physiology- Advanced Genetics and Molecular Biology (Lab Instructor)- Introduction to Biological Sciences (Lab Instructor)Enjoyed mentoring students in the lab:- Assigned and managed student projects.- Trained students in lab safety and skills (surgery, microscopy, histology).- Encouraged student presentation of research, resulting in numerous poster awards.- Take pride that many of students are now professional clinicians and researchers.

Phd, Neurobiology

Bs, Biology, With Minors In Psychology, Chemistry, Business