Anna Dahlman Email & Phone Number

Copenhagen, DK

Copenhagen Metropolitan Area

Copenhagen Area, Denmark

• Develop and execute nonclinical safety evaluations strategies based on intended pharmacologic effect, therapeutic indication and international guidelines and best practice.
• Design, monitor, interpret and report nonclinical safety and toxicity studies conducted at CROs.
• Represent non-clinical safety on cross functional global development teams.
• Develop and manage timelines for external and internal deliverables for CTA/IND enabling documents. Initiate and lead subteams. Ensure justification of the preclinical species.
• Author non-clinical safety sections of IND/CTA/IMPDs. Represent nonclinical safety in authority interactions such as scientific advice and pre-IND meetings.
• For compounds in clinical development, review DSURs and functional representative in Safety committee meetings.

Lund, Sweden

• Responsible for planning and conducting nonclinical safety and toxicology studies supporting the development of therapeutic antibodies in immuno-oncology, including three successful CTA submissions.The role included a.
• Evaluation of new CROs, request for proposals, site visits, and scientific support at audits
• Planning study dates, requesting study quotes, managing contracts
• Managing the budget for the nonclinical studies
• Designing, monitoring, and interpreting results from nonclinical toxicology studies (non-GLP and GLP; in vitro and in vivo), with consideration to pharmacological mode-of-action, and ensuring regulatory compliance
• Prepare nonclinical toxicology sections in clinical trial application documents (IB and Clinical study protocol).

Lund, Sweden

As a scientist at Alligator Bioscience, my role was to be the Preclinical Safety Lead for three drug development projects at Alligator Bioscience. The projects involve therapeutic antibodies, bispecific and monoclonal, for use as tumor targeted immune activating compounds in cancer patients. In a small sized company as Alligator, the role as Preclinical.

Faculty Of Medicine

Organizing and compiling the experiences from a pilot test of the new national clinical guideline for palliative care (Nationell Vårdplan för Palliativ vård, NVP). Authored the case study paper 'A novel care guide for personalized palliative care - a national initiative for improved quality of care' published in BMC Palliative Care.

Copenhagen Area, Denmark

In my role as a Scientist in the Department for Preclinical Pharmacology and Toxicology, I provided expertize in cell-based assays for drug discovery and development. I designed, performed, and analyzed in vitro experiments for mode-of-action studies and anti-tumor efficacy through to IND. Set up and evaluation of biomarkers for efficacy and tissue-cross.

Faculty Of Medicine

Faculty Of Medicine

During my doctoral studies I investigated the potential role of MSMB and CRISP-3 as prognostic biomarkers for prostate cancer progression. This included manual and automated immunohistochemical analysis of prostate cancer tissue from patients, as well as a wide range of laboratory techniques characterizing gene and protein expression, cell culture, small.

Cancer Research Unit, York University, Yorkshire, UK

Technical and methodological training in sorting subpopulations of cells from primary prostate cancer tissue, based on their difference in morphology and surface receptors.

In teh Department of Laboratory Medicine, Division of Molecular Medicine, I studied how arsenic trioxide can induce differentiation and cell death in neuroblastoma tumor cells.

In the Department for Cell and Organism Biology, Division of Molecular genetics, I worked on characterizing genetic control of telomerase length in Saccharomyces yeast cells.

Phd, Medical Science

Activities and Societies: Representative at the Department board (2007-2008), board member of the Medical PhD council (2009-2011), member.

Master'S Degree, Medicine

Thesis title: Arsenic Trioxide Induced Cell Death in Multidrug Resistant Neuroblastoma Cells: Expression Pattern of Selected Genes

Bsc, Biology

Activities and Societies: Board member of Friskis&Svettis, Växjö. In charge of the 'Members Section', responsible for all communication to.