• Supervise the team of research executives and associate to execute the projects within given time• Evaluating the cost effective route for the synthesis of the API and intermediates thereof via close look on the literature survey of the molecules• Scrutinizing the viable routes and execution of work with proper safety and regulations as per GMP• Propose the specification for the raw materials and intermediates involved in process, Structure Elucidation Report generation by… Show more • Supervise the team of research executives and associate to execute the projects within given time• Evaluating the cost effective route for the synthesis of the API and intermediates thereof via close look on the literature survey of the molecules• Scrutinizing the viable routes and execution of work with proper safety and regulations as per GMP• Propose the specification for the raw materials and intermediates involved in process, Structure Elucidation Report generation by evaluation of the molecules using analytical techniques such as IR Spectroscopy, NMR (1H, 13C, APT, DEPT etc.), Mass Spectrometry etc.• Worked on API’s such as Teneligliptin, Etoricoxib, Pregabalin, Brexpiprazole, Metoprolol Succinate, Metoprolol Trartrate, Duloxetin, Fenofibrate, Lurasidone Hydrochlorid, Deferasirox, Flibanserin, Derifenacin, Rosuvastatin Calcium and Rifaximin Show less

• Supervise the team of research executives and associate to execute the projects within given time • Deciding the coast effective route of synthesis and valuable input in process development to offer simpler isolation and eventually delivery of compounds in given timeline• Working on API’s such as Alogliptin benzoate, purification Sugammadex Sodium Salt (γ-Cyclodextrin derivative), Lumacaftor Intermediates, Eribuline intermediates and Sacubitril calcium• Characterization of… Show more • Supervise the team of research executives and associate to execute the projects within given time • Deciding the coast effective route of synthesis and valuable input in process development to offer simpler isolation and eventually delivery of compounds in given timeline• Working on API’s such as Alogliptin benzoate, purification Sugammadex Sodium Salt (γ-Cyclodextrin derivative), Lumacaftor Intermediates, Eribuline intermediates and Sacubitril calcium• Characterization of molecules using modern analytical tools and preparation of Structure elucidation report for the same Show less

• Worked on Dotz Benzannulation/Pentannulation and application in natural product synthesis• Total synthesis of biologically active (-)-asteriscunolide C• Weekly report discussion with supervisor and weekly presentation on various topics of Synthetic Organic Chemistry• Purification, Analysis and Characterization of compounds with modern analytical tools

• Literature for the API’s, viable synthetic route discussion, planning of work accordingly, execution of work within time line and supervise the subordinates for the experiments• Daily meeting for the update of the planning and weekly meeting with the management for the development of R&D stuffs• Worked on API’s such as Carfilzomib (Resulted in publication of patent later on) Alogliptin, Sugammadex Sodium Salt (γ-Cyclodextrin derivative), Bedaquiline, Anidulafungine, Mecafungine… Show more • Literature for the API’s, viable synthetic route discussion, planning of work accordingly, execution of work within time line and supervise the subordinates for the experiments• Daily meeting for the update of the planning and weekly meeting with the management for the development of R&D stuffs• Worked on API’s such as Carfilzomib (Resulted in publication of patent later on) Alogliptin, Sugammadex Sodium Salt (γ-Cyclodextrin derivative), Bedaquiline, Anidulafungine, Mecafungine including their side chain synthesis Show less

• Planning of routine experiments, reporting to senior supervisor, training to subordinates and maintaining lab experiments records as well as chemical consumption records• Carried out Will-Gerrodt reaction, worked on various Pd based catalysts for Suzuki Coupling and synthesis of diamides by using different aromatic amines, performed Grignard Reaction and Birch Reduction• Worked on API product like Disopyramide phosphate

• Plan the allotted work, synthesize targeted molecules in time and maintain the lab records• Carried out variety of organic reactions namely Suzuki coupling, ortho-lithiation of amides and anilides (using n-BuLi, condensation with various electrophiles), Grignard Reaction, Mitsunobu reaction, Wittig reaction, Buchwald Hartwig coupling, Birch reduction, Robinson Schopf synthesis of Tropanone• Reduction of Various functional groups have also been carried out using Pd/C, Raney Ni, LiAlH4,… Show more • Plan the allotted work, synthesize targeted molecules in time and maintain the lab records• Carried out variety of organic reactions namely Suzuki coupling, ortho-lithiation of amides and anilides (using n-BuLi, condensation with various electrophiles), Grignard Reaction, Mitsunobu reaction, Wittig reaction, Buchwald Hartwig coupling, Birch reduction, Robinson Schopf synthesis of Tropanone• Reduction of Various functional groups have also been carried out using Pd/C, Raney Ni, LiAlH4, NaBH4, NaBH3CN, DIBAL-H, H2/Pt etc• Similarly oxidizing agents like PCC, MnO2, and Peracids have been used successfully• Synthesis of heterocyclic compounds on 50 mg to 500 g scale• Well acquainted with purification of organic compounds by crystallization, column chromatography and chromatotron (separation of compounds in 50-100 mg quantity)• Interpretation and characterization of organic compounds by IR, Mass, 1H-NMR, 13CNMR, GC, GC-MS and HPLC Show less