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Duke Street Bio (2021-current)Small molecule drug discovery and development in DNA damage repair and cancer immunotherapyCumulus Oncology (2020-2022)Cumulus Oncology develops anti-cancer therapies for clinical settings in areas of high unmet needIOmet Pharma Ltd (2010-2018)Small molecule drug discovery and development in cancer immunotherapy and metabolismScottish Enterprise (2009-2010)Senior Executive Life Sciences: Developing strategies for supporting and developing drug discovery and drug delivery within ScotlandGlaxoSmithKline Research and Development (1997-2009)Section Head, Cell-Based Compound Profiling, (2005-09)In addition, transnational matrix role as line representative to internal Drug Discovery Portfolio Committee responsible for Neuroscience Area o Strategic role influencing selection and management of appropriate targets for Target-to-Lead drug discovery initiativeso Direct impact on programme planning and implementation of appropriate critical paths to facilitate effective progression of drug discovery programmes Project Leader (1999-2004)• Leading multi-disciplinary project teams - 7TM receptor programmes associated with dyslipidaemia, asthma and obstructive pulmonary disease areas• Establishing working relationships with scientists from varying disciplinary backgrounds at GlaxoSmithKline UK, USA and European sitesOrphan 7TM receptor program co-chair (May 2003-May 2004) Responsible for devising strategies to characterise orphan 7TM receptors within GSK and to oversee coordination of screening effortsAchievements in Exploratory Science (1994-2009)Identification of novel ligand:orphan 7TM receptor pairingsDiscovery of 7TM receptor heterodimerisation and elucidation of mechanisms Biochemistry and pharmacological significance of 7TM receptor accessory proteins7TM receptor allosterism7TM receptor/G protein fusions as research and screening toolsOral presentations:• Invited speaker to numerous international symposium, primarily focused on 7TM Receptors and Screening TechnologiesSpecialties: Expertise in GPCR research. Seen as a key contributor in this field from both a pharmaceutical and academic perspective
Duke Street Bio Ltd
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Duke Street Bio LtdEdinburgh, Gb
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Chief Executive OfficerDuke Street Bio Ltd Sep 2021 - Present
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Biotech ConsultantAw Consulting Jun 2018 - Present
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Scientific ConsultantCumulus Oncology Aug 2021 - Sep 2022Edinburgh, Scotland, Gb -
Chief Executive OfficerModulus Oncology Ltd. Aug 2020 - Aug 2021
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CeoIomet Pharma Oct 2015 - May 2018Edinburgh, Gb -
Head Of BiologyIomet Pharma Dec 2010 - Sep 2015Edinburgh, Gb -
Senior ExecutiveScottish Enterprise Sep 2009 - Dec 2010Glasgow, Glasgow City, GbI work within the Life Sciences Strategy group at Scottish Enterprise. My particular areas of focus are drug discovery and drug delivery. -
Section HeadGlaxosmithkline Jan 2005 - Sep 2009Brentford, Middlesex, GbCurrent role: Section Head, Cell-Based Compound Profiling, Screening and Compound Profiling Department (2005-present)• Line management of cell based screening and compound profiling group (20 scientists) o Managing a portfolio of cell-based assays across a variety of target classes and high throughput assay technologies to support Structure Activity Relationship (SAR) initiatives for Hit-to-Lead and lead optimisation drug discovery programmes -
Section HeadGlaxosmithkline 1997 - 2009Brentford, Middlesex, Gb -
Post-Doctorate FellowUniversity Of Glasgow 1994 - 1996
Alan Wise Skills
Alan Wise Education Details
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University Of LeedsBiochemistry -
University Of LeedsBiochemistry
Frequently Asked Questions about Alan Wise
What company does Alan Wise work for?
Alan Wise works for Duke Street Bio Ltd
What is Alan Wise's role at the current company?
Alan Wise's current role is Chief Executive Officer at Duke Street Bio Ltd.
What is Alan Wise's email address?
Alan Wise's email address is al****@****pgd.com
What schools did Alan Wise attend?
Alan Wise attended University Of Leeds, University Of Leeds.
What skills is Alan Wise known for?
Alan Wise has skills like Drug Discovery, Biochemistry, Cell, Lifesciences, Drug Development, Biotechnology, Assay Development, Science, Gpcrs, In Vitro, Neuroscience, Protein Chemistry.
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