Alan Wise Email & Phone Number

Duke Street Bio (2021-current)Small molecule drug discovery and development in DNA damage repair and cancer immunotherapyCumulus Oncology (2020-2022)Cumulus Oncology develops anti-cancer therapies for clinical settings in areas of high unmet needIOmet Pharma Ltd (2010-2018)Small molecule drug discovery and development in cancer immunotherapy and metabolismScottish Enterprise (2009-2010)Senior Executive Life Sciences: Developing strategies for supporting and developing drug discovery and drug delivery within ScotlandGlaxoSmithKline Research and Development (1997-2009)Section Head, Cell-Based Compound Profiling, (2005-09)In addition, transnational matrix role as line representative to internal Drug Discovery Portfolio Committee responsible for Neuroscience Area o Strategic role influencing selection and management of appropriate targets for Target-to-Lead drug discovery initiativeso Direct impact on programme planning and implementation of appropriate critical paths to facilitate effective progression of drug discovery programmes Project Leader (1999-2004)• Leading multi-disciplinary project teams - 7TM receptor programmes associated with dyslipidaemia, asthma and obstructive pulmonary disease areas• Establishing working relationships with scientists from varying disciplinary backgrounds at GlaxoSmithKline UK, USA and European sitesOrphan 7TM receptor program co-chair (May 2003-May 2004) Responsible for devising strategies to characterise orphan 7TM receptors within GSK and to oversee coordination of screening effortsAchievements in Exploratory Science (1994-2009)Identification of novel ligand:orphan 7TM receptor pairingsDiscovery of 7TM receptor heterodimerisation and elucidation of mechanisms Biochemistry and pharmacological significance of 7TM receptor accessory proteins7TM receptor allosterism7TM receptor/G protein fusions as research and screening toolsOral presentations:• Invited speaker to numerous international symposium, primarily focused on 7TM Receptors and Screening TechnologiesSpecialties: Expertise in GPCR research. Seen as a key contributor in this field from both a pharmaceutical and academic perspective

Listed skills include Drug Discovery, Biochemistry, Cell, Lifesciences, and 10 others.