Alanne Rayssa Melo Email and Phone Number
I’m a PhD researcher in the field of Molecular Biology, who has a great passion for science. I worked in different areas of knowledge of Biological Sciences, with emphasis on the area of virology (HPV), vaccine development subfield (Science and Technology/Innovation). During my Ph.D., I researched a therapeutic DNA vaccine against cervical cancer in a pre-clinical model. In addition, throughout my scientific training, I carried out research in the fields of population genetics (genetic polymorphisms), plant breeding (in vitro micropropagation) and epigenetics (DNA methylation analysis). During my doctorate, I participated in two sandwich Doctorate internships abroad at the Istituto Nazionale Tumori Regina Elena, in Rome – Italy. During my undergraduate, master's and doctoral studies, I accumulated around 500 hours of teaching internships for elementary, secondary and higher education students, holding theoretical and practical classes in the laboratory. Through years of research, I have collaborated in the writing of scientific papers and books; I have participated in National and International Congresses (Brazil and Italy) with presentation of works in oral and poster modalities; In addition to having been part of the review boards in more than 10 undergraduate theses.As interpersonal skills I can highlight: self-management ability; great ability to work in a team with easy interaction with people; adaptation to new work environments and new research areas; ability to express myself in 3 languages (portuguese, english and italian); curiosity and passion for biomedical research; resilience and persistence when facing difficulties and willingness to learn. My mission is to contribute to the research of difficult-to-manage diseases, such as cancer, thus improving the quality of life of patients.
Unifip Centro Universitário
View- Website:
- unifip.edu.br
- Employees:
- 21
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Professor In A Postgraduate Course In Clinical HematologyUnifip Centro Universitário May 2023 - PresentJoão Pessoa, Paraíba, BrazilProfessor of the Specialization course in Clinical Hematology at Faculdade UNIFIP (João Pessoa Unit), where I teach classes divided into modules for postgraduate classes. -
Molecular BiologistLacen - Pb Sep 2022 - PresentJoão Pessoa, Paraíba, BrazilI perform diagnostic tests in the Immunology, Molecular Biology and Neonatal Screening sectors of the Central Public Health Laboratory in the state of Paraíba (LACEN - PB) - Brazil. Diagnostics include ELISA (diagnosis of various pathogens), Flow cytometry for CD4 and CD8 T lymphocytes counts in patients with HIV, Chemiluminescence (diagnosis of various pathogens), and RT-qPCR for detection of SARS-CoV-2.
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Molecular BiologistLaboratório Maurílio De Almeida Feb 2022 - Sep 2022João Pessoa, Paraíba, BrazilRole of clinical analyst in the Molecular Biology sector of the Maurílio de Almeida Laboratory, where I was responsible for diagnosing the SARS-CoV-2 virus through RTq-PCR analysis during the pandemic.
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Phd In Genetics: Development Of Multi-Epitope Dna Vaccine As Immunotherapy Against Cervical CancerUniversidade Federal De Pernambuco Mar 2017 - Nov 2021Recife, Pernambuco, BrazilPhD in Genetics in the field of virology (human papillomavirus), vaccine development sub-area (Science and Technology/Innovation), where I researched a therapeutic DNA vaccine against cervical cancer in a pre-clinical model. During my doctorate in Brazil, I participated in two Sandwich doctorate internships abroad (2018 and 2019) at the Istituto Nazionale Tumori Regina Elena, in Rome – Italy, under the supervision of the researcher Dr. Aldo Venuti, each internship lasting 6 months (August 2018 - February 2019; February 2020 – August 2020). -
Phd In Genetics - Dna Vaccine DevelopmentIfo - Istituto Nazionale Tumori Regina Elena - Istituto Dermatologico San Gallicano Aug 2018 - Aug 2020Rome, Latium, ItalyDuring my PhD in Genetics (virology field - human papillomavirus; and Vaccine Development sub-area - Science and Technology/Innovation) I researched a therapeutic DNA multiepitope vaccine against cervical cancer in a pre-clinical model using the immunomodulator Ii-PADRE as an adjuvant for the activation of the helper response. Our data revealed that it is possible to observe a slight trend towards an increase in Th1 cytokines, lower tumor density, and lower pleomorphism in tumors of animals immunized with the plasmid multi E7 associated with Ii-PADRE, which may indicate a possible immunogenic potential of this vaccine strategy for inducing a protective cellular response. The research carried out by our group contributes to the search for increasing the survival of patients with tumors caused by HPV, a highly disseminated virus in the population. -
Doctoral StudentIfo - Istituto Nazionale Tumori Regina Elena - Istituto Dermatologico San Gallicano Aug 2018 - Aug 2020Rome, Latium, Italy -
Master'S Degree Student In Cellular And Molecular BiologyUniversidade Federal Da Paraíba Mar 2013 - Mar 2015João Pessoa, Paraiba, BrazilDuring the master's I developed research in the field of epigenetics, and researched the relationship between sun exposure and skin cancer, through the analysis of DNA methylation in promoter regions of proto oncogenes and microRNA genes with tumor suppressor function. To this purpose, skin samples were analyzed, which were obtained from sun-exposed and sun-protected areas from 28 corpses of both sexes, aged 30-89 years with no history of skin diseases obtained from the Brazilian Service of Death Investigation. Then, the skin samples were submitted to DNA methylation analysis using Methylation Specific PCR (MSP) by previous modification of the DNA with sodium bisulfite. The research project is entitled: Influence of sun exposure on the DNA methylation profile of the MMP9 and MIR137 genes in skin cells. With this work, I won a Young Geneticist award -1 st place, master's level - during an oral presentation at the XX Genetics Meeting of the Northeast ENGENE (Brazil - 2014). -
Undergraduate Student In Biological Sciences (Licentiate And Bachelor'S Degree)Universidade Estadual Da Paraíba Mar 2008 - Jun 2012Campina Grande, Paraiba, BrazilDuring graduation I participated in the Brazilian Scientific Initiation Program (PIBIC), where I worked in the field of Population genetics, carrying out research on the association of genetic polymorphisms (microsatellite genotyping) in patients with Congenital Hypothyroidism, a rare disease. This work became my graduate thesis. The research project is entitled: Microsatellite genotipation of the TPO gene in patients with Congenital Hypothyroidism. -
Scholarship Graduate StudentEmbrapa 2010 - 2011Campina Grande, Paraiba, BrazilDuring graduation I participated in the Brazilian Scientific Initiation Program (PIBIC), at the Brazilian Agricultural Research Corporation named EMBRAPA - cotton subdivision. At that time I had the opportunity to develop research in the field of plant genetic improvement - in vitromicropropagation subfield, and I worked with the in vitro cultivation techniques forthe species Agave sisalana. Title of the research project: In vitro propagation of bulb of the Agave sisalana species
Alanne Rayssa Melo Education Details
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Molecular Genetics -
Epigenetics, Dna Methylation, Skin Cancer, Microrna, Solar Radiation, Mmp -
Population Genetics, Genetic Polymorphisms, Microsatellite Genotyping
Frequently Asked Questions about Alanne Rayssa Melo
What company does Alanne Rayssa Melo work for?
Alanne Rayssa Melo works for Unifip Centro Universitário
What is Alanne Rayssa Melo's role at the current company?
Alanne Rayssa Melo's current role is Researcher and professor in the fields of Molecular Biology and Immunology - PhD in Genetics.
What schools did Alanne Rayssa Melo attend?
Alanne Rayssa Melo attended Universidade Federal De Pernambuco, Universidade Federal Da Paraíba, Universidade Estadual Da Paraíba.
Who are Alanne Rayssa Melo's colleagues?
Alanne Rayssa Melo's colleagues are Tamíris Brasileiro, Allana Azevedo, Joseilson Carlos, Aislânia Alves, Mary Dutra, Daneelly Henrique, Amanda Nammur.
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