Alavian is a professor of medicine and hepatologist, he established the first hepatitis clinic in 1995, at the Iranian Blood Transfusion Service in Tehran, and he is one of the founders of the Iranian Charity for Liver Support in Tehran, established in 1995. He has been the associate editor of the Journal of Clinical Virology from 2004, and an advisor and consultant on national program projects for the control of hepatitis in Iran. He has been a member of the National Committee for Hepatitis in the Iranian Ministry of Health and Medical Education since 1995. Alavian is an experienced researcher and hepatologist who has been actively involved in various national multicenter clinical trials and basic scientific projects related to viral hepatitis over the past 19 years. He has authored/co-authored over 320 articles in both local and international journals. He was the principal investigator in numerous clinical trials related to the management and treatment of hepatitis C and B patients. His main interests are; health policy, epidemiological aspects of viral hepatitis, and methods of integrating new protocols for the control of these infections. He is also interested in clinical trials of emerging medications for hepatitis B virus and hepatitis C virus infections, along with the treatment of viral hepatitis in particular diseases, including thalassemia and hemophilia. He is the founder and director of the Middle East Liver Disease (MELD) Centers which were established in Iran, in 2012, and the program has expanded throughout the entire region with the collaboration of scientists in both Middle East and Middle Asian countries.