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Biomedical scientist who has conducted extensive research focused on immuno-oncology, T cell therapy, neutrophils, and monocytes studies, autoimmune studies, purinergic signaling, hypoxia, wound healing, nerves, ocular tissue, exocrine glands, live-cell imaging, EGFRs, GPCRs and NMDA signaling in biochemistry, neuroscience, and immunology.
Stealth Mode Startup Biotech
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Principal Scientist / AdStealth Mode Startup Biotech Oct 2021 - PresentLead immunology/oncology projects developing drug candidates for immuno-oncology therapies.- target engagement, validation, and profiling of lead candidates. - Assay development and functional readouts using both innate and adaptive immune cells.-Principal scientist from Oct 2021 to Apr 2022
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Senior ScientistKymera Therapeutics Oct 2020 - Oct 2021Watertown, Ma, UsServe on immunology projects developing targeted protein degradation to treat myeloid/lymphocyte-mediated diseases.- Developed cellular-based assays to evaluate the effect of the degrading disease-causing proteins in T cells using multiple autoimmune settings.-Initiated the ideation and execution of studies to evaluate the new targets for the next generation of degraders. -
ScientistRubius Therapeutics Oct 2018 - Oct 2020Cambridge, Massachusetts, UsAdvancing discovery group projects involving Immuno-oncology/autoimmune targets - Worked on Artificial antigen presenting cells (RTX-321) projects for enhancing antigen specific T cell mediated anti-cancer activity - Performed preclinical IND-enabling studies and drafted/submitted IND studies for RTX-321 - Initiated and validated CAR-T cell projects - Leading autoimmune projects discovery group, advancing artifical APC projects to improve the efficacy of anti-cancer cell therapies. -
Postdoctoral Researcher, Immuno-Oncology, Bioscience Division Of SriSri International Feb 2017 - Sep 2018Menlo Park, Ca, UsServe on immunotherapy research projects targeting human endogenous retrovirus to develop anti-tumor immunotherapy for solid tumors including breast, pancreatic, and ovarian cancers.- Identified antibodies against HERV-K generated from cancer patient samples including blood, serum and tissue. - Led in vivo prevention/vaccination studies using a mouse tumor model challenged with melanoma and breast cell lines. Generation of HERV-K targeted CART.- Identified functional T cell receptor pairs (αβ chains) expressed by a single tumor infiltrating T cell from breast cancer patients to develop TCR therapy specific to human endogenous retrovirus-K. -Investigated interplay between human endogenous retrovirus and Ras-oncogenes during tumor growth and metastasis. Performed a high throughout FDA approved drug-screening studies to determine anti-tumor effects. -
Postdoctoral Research FellowUniversity Of California, San Francisco Dec 2015 - Dec 2017San Francisco, California, UsServe on research projects, validating the efficacy of pre-clinical trial stage therapy for treating autoimmune-induced dry eye disease, neuropathy and exocrinopathy.-Led clinical research projects focused on neuro-immunology using autoimmune murine models (AIRE KO and CD28KO mouse models). Identification of biomarkers for nerves and stem cells for the glands.- Investigated T-cell induced chronic inflammation on innervation/neurodegeneration of the cornea, eyes and exocrine glands in Sjogren’s syndrome. -
Postdoctoral FellowHarvard Medical School/Bidmc Sep 2013 - Nov 2015Boston, Ma, UsServed on research team, under the direction of Dr. Wolfgang Junger, whose lab focuses on the clinical studies of immune cells including monocytes/neutrophils/T-cells in sepsis patients.• Characterized interactions between Toll-like receptors (TLRs) and purinergic signaling involving mitochondria that regulate NLRP3 inflammasome activation using human immune cells. • Isolated primary immune cells to examine pharmacological assays to elucidate NLRP3 inflammasome activation involving NLRP3, ASC oligomerization, and caspase-1 activation. • Characterized the role of mitochondria and autocrine purinergic signaling in primary human monocytes.• Investigated Cecal Ligation and Puncture (CLP) mice to study immunological changes that occur with sepsis. -
Phd Candidate/Research FellowBoston University School Of Medicine 2008 - 2013Boston, Ma, UsLab focuses on elucidating wound healing mechanisms that occur during repair of epithelium, neurons and extracellular matrix, using the cornea as a wound model. Thesis: Hypoxia induced alterations in the wound healing processes of the cornea: Ca2+ mobilization that occurs between neuronal and epithelial cells post-injury and the protein regulation involved in cell migration and re-assembly of the matrix. (Advisor: Dr. Vickery Trinkaus-Randall) -
Junior AnalystCovance 2006 - 2008Princeton, New Jersey, UsTechnical Analyst IIFunctioned as lead scientist in assisting companies to optimize protocol to meet their scientific needs according to standard operating procedures. • Perform experimental assays to assure the quality of commercial products.• Communicate with clients to optimize the protocol for their business.• Comprehensive onsite service to maximize customer satisfaction.• Performed assays including HPLC/GC to determine nutritional values in products.
Albert Lee Skills
Albert Lee Education Details
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Boston University School Of MedicineBiochemistry -
University Of Wisconsin-MadisonBiochemistry
Frequently Asked Questions about Albert Lee
What company does Albert Lee work for?
Albert Lee works for Stealth Mode Startup Biotech
What is Albert Lee's role at the current company?
Albert Lee's current role is Dedicated scientist skilled in conducting extensive research focused on immunology and managing research projects/groups.
What is Albert Lee's email address?
Albert Lee's email address is al****@****stx.com
What is Albert Lee's direct phone number?
Albert Lee's direct phone number is +160846*****
What schools did Albert Lee attend?
Albert Lee attended Boston University School Of Medicine, University Of Wisconsin-Madison.
What are some of Albert Lee's interests?
Albert Lee has interest in Economic Empowerment, Politics, Investing, Education, New Technologies, Science And Technology, Disaster And Humanitarian Relief, Human Rights, Health.
What skills is Albert Lee known for?
Albert Lee has skills like Protein Chemistry, Molecular Biology, Cell Culture, Research, Public Speaking, Immunofluorescence, Assay Development, Western Blotting, Biochemistry, Pcr, Teaching, Microsoft Office.
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