Alex Cornean, Phd Email and Phone Number
I'm a Developmental Genetics graduate from Heidelberg University. I have over eight years of experience pioneering biomedical research and a profound data science knowledge. My career is dedicated to transforming scientific inquiry and healthcare through technology.Director, Databound Limited—Databound specialises in delivering custom cloud solutions across various sectors. Our expertise in creating trusted research environments has set the stage for our next venture.Co-founder and CEO, DataHarmony - Our platform will be a game-changer for the biomedical and life sciences sectors. It accelerates innovation in the life sciences by streamlining data management and processing. Our cloud-based solution provides tailored computing resources, making advanced research technologies accessible and efficient for scientists and companies of all sizes everywhere. This accelerates development cycles and gives you complete command over your valuable data assets. We are excited to already work with a few research teams and are eager to expand our engagements with other private and academic research teams.Lead, Genome Engineering at Heidelberg University - In the Freichel lab, I continue to guide a talented team using cutting-edge CRISPR technologies for cardiovascular disease modelling and gene therapy projects. As my focus increasingly shifts towards expanding DataHarmony, I am progressively transitioning responsibilities at Heidelberg to dedicate more to advancing global research through our innovative platform.I am very passionate about - improving people's lives by contributing to and enabling gene therapy, genetics and biomedical research as a whole- helping transform companies' digital landscape- working towards carbon neutrality- long-distance trail running and multi-day trekking expeditionsIf you are 1) as excited about biomedical research as I am, 2) are facing issues with research data storage, management and analysis, or3) discuss ways in which bleeding edge digital solutions could be shaped to transform your research,feel free to reach out via DM and I'd be happy to send a calendly link, upon request, to book a meeting.
Dataharmony
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Co-Founder And CeoDataharmony Dec 2023 - PresentUnited KingdomDataHarmony's mission is to empower public and private research institutions in the life sciences by simplifying data management and analysis and fostering collaboration to accelerate life-changing breakthroughs in biomedicine. To achieve this, we are building an AI-powered data management and processing co-pilot for life sciences. -
Director And Chief Information OfficerDatabound Limited May 2020 - PresentUnited Kingdom -
Subgroup LeaderUniversity Hospital Heidelberg Oct 2022 - PresentHeidelberg, Baden-Württemberg, GermanyExploring genome engineering tools in the Freichel lab together with a small team of students and researchers.Focus on disease modelling (cardiovascular mostly) using Adenine and Cytosine Base Editors (ABEs/CBEs) and Prime Editors, as well as old-school CRISPR-based Homology Directed Repair in mice and human iPS cells. New projects on pre-clinical gene therapy using CBEs.Co-authored publications:Streamlined Generation of CRISPR/Cas9-Mediated Single-Cell Knockout Clones in Murine Cell Lines (Hub et al. 2024, ACS Pharmacol. Transl. Sci.): https://doi.org/10.1021/acsptsci.3c00338 -
Phd CandidateUniversity Of Heidelberg Oct 2017 - Jul 2022Heidelberg Area, GermanyWittbrodt lab (at Centre for Organismal Studies)- Focus on developmental genetics and the development of genome engineering tools- Thesis title: "The role of the medaka protein O-mannosyltransferase 2 across tissues, development and dystroglycanopathies." https://archiv.ub.uni-heidelberg.de/volltextserver/32151/1/202205_PhDThesis_AC_pdfA.pdfCo-authored publications:1. Boosting targeted genome editing using the hei-tag (Thumberger et al. 2022, eLife): https://doi.org/10.7554/eLife.705582. Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction (Cornean et al. 2022, eLife): https://doi.org/10.7554/eLife.721243. CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease (Doering et al. 2023, Disease Models and Mechanisms): https://doi.org/10.1242/dmm.049811 -
Master Thesis StudentUniversity Of Heidelberg Apr 2017 - Sep 2017HeidelbergWittbrodt lab (at the Centre for Organismal Studies) -
Visiting StudentCancer Research Uk Cambridge Institute Sep 2016 - Jan 2017Cambridge, United KingdomHannon labon a CRUK-CI summer studentship -
Visiting StudentHelmholtz Munich Apr 2015 - Jul 2015Neuherberg, MünchenDesbordes lab -
Bachelor ThesisJohannes Kepler Universität Linz Jul 2014 - Sep 2014LinzPohl lab, supervised by Prof Andreas HornerInstitute of BiophysicsOverexpression, purification and reconstitution of various AQP4 protein variants into artificial lipid vesicles with subsequent stopped-flow analysis.Co-authored one publication: Positively charged residues at the channel mouth boost single-file water flowAndreas Horner*, Christine Siligan*, Alex Cornean and Peter Pohl*equal contributionhttps://doi.org/10.1039/C8FD00050F
Alex Cornean, Phd Education Details
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Genetics / Genome Engineering -
Molecular Biosciences, Major Developmental & Stem Cell Biology -
Molecular Biosciences -
First Class
Frequently Asked Questions about Alex Cornean, Phd
What company does Alex Cornean, Phd work for?
Alex Cornean, Phd works for Dataharmony
What is Alex Cornean, Phd's role at the current company?
Alex Cornean, Phd's current role is Co-founder & CEO @ DataHarmony, Director @ Databound Limited | Biomedical Scientist.
What schools did Alex Cornean, Phd attend?
Alex Cornean, Phd attended Heidelberg University, Heidelberg University, Universität Salzburg, Cardiff University / Prifysgol Caerdydd.
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