Alex Cornean, Phd

Alex Cornean, Phd Email and Phone Number

Co-founder & CEO @ DataHarmony, Director @ Databound Limited | Biomedical Scientist @ DataHarmony
Alex Cornean, Phd's Location
Freiburg, Baden-Württemberg, Germany, Germany
About Alex Cornean, Phd

I'm a Developmental Genetics graduate from Heidelberg University. I have over eight years of experience pioneering biomedical research and a profound data science knowledge. My career is dedicated to transforming scientific inquiry and healthcare through technology.Director, Databound Limited—Databound specialises in delivering custom cloud solutions across various sectors. Our expertise in creating trusted research environments has set the stage for our next venture.Co-founder and CEO, DataHarmony - Our platform will be a game-changer for the biomedical and life sciences sectors. It accelerates innovation in the life sciences by streamlining data management and processing. Our cloud-based solution provides tailored computing resources, making advanced research technologies accessible and efficient for scientists and companies of all sizes everywhere. This accelerates development cycles and gives you complete command over your valuable data assets. We are excited to already work with a few research teams and are eager to expand our engagements with other private and academic research teams.Lead, Genome Engineering at Heidelberg University - In the Freichel lab, I continue to guide a talented team using cutting-edge CRISPR technologies for cardiovascular disease modelling and gene therapy projects. As my focus increasingly shifts towards expanding DataHarmony, I am progressively transitioning responsibilities at Heidelberg to dedicate more to advancing global research through our innovative platform.I am very passionate about - improving people's lives by contributing to and enabling gene therapy, genetics and biomedical research as a whole- helping transform companies' digital landscape- working towards carbon neutrality- long-distance trail running and multi-day trekking expeditionsIf you are 1) as excited about biomedical research as I am, 2) are facing issues with research data storage, management and analysis, or3) discuss ways in which bleeding edge digital solutions could be shaped to transform your research,feel free to reach out via DM and I'd be happy to send a calendly link, upon request, to book a meeting.

Alex Cornean, Phd's Current Company Details
DataHarmony

Dataharmony

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Co-founder & CEO @ DataHarmony, Director @ Databound Limited | Biomedical Scientist
Alex Cornean, Phd Work Experience Details
  • Dataharmony
    Co-Founder And Ceo
    Dataharmony Dec 2023 - Present
    United Kingdom
    DataHarmony's mission is to empower public and private research institutions in the life sciences by simplifying data management and analysis and fostering collaboration to accelerate life-changing breakthroughs in biomedicine. To achieve this, we are building an AI-powered data management and processing co-pilot for life sciences.
  • Databound Limited
    Director And Chief Information Officer
    Databound Limited May 2020 - Present
    United Kingdom
  • University Hospital Heidelberg
    Subgroup Leader
    University Hospital Heidelberg Oct 2022 - Present
    Heidelberg, Baden-Württemberg, Germany
    Exploring genome engineering tools in the Freichel lab together with a small team of students and researchers.Focus on disease modelling (cardiovascular mostly) using Adenine and Cytosine Base Editors (ABEs/CBEs) and Prime Editors, as well as old-school CRISPR-based Homology Directed Repair in mice and human iPS cells. New projects on pre-clinical gene therapy using CBEs.Co-authored publications:Streamlined Generation of CRISPR/Cas9-Mediated Single-Cell Knockout Clones in Murine Cell Lines (Hub et al. 2024, ACS Pharmacol. Transl. Sci.): https://doi.org/10.1021/acsptsci.3c00338
  • University Of Heidelberg
    Phd Candidate
    University Of Heidelberg Oct 2017 - Jul 2022
    Heidelberg Area, Germany
    Wittbrodt lab (at Centre for Organismal Studies)- Focus on developmental genetics and the development of genome engineering tools- Thesis title: "The role of the medaka protein O-mannosyltransferase 2 across tissues, development and dystroglycanopathies." https://archiv.ub.uni-heidelberg.de/volltextserver/32151/1/202205_PhDThesis_AC_pdfA.pdfCo-authored publications:1. Boosting targeted genome editing using the hei-tag (Thumberger et al. 2022, eLife): https://doi.org/10.7554/eLife.705582. Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction (Cornean et al. 2022, eLife): https://doi.org/10.7554/eLife.721243. CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease (Doering et al. 2023, Disease Models and Mechanisms): https://doi.org/10.1242/dmm.049811
  • University Of Heidelberg
    Master Thesis Student
    University Of Heidelberg Apr 2017 - Sep 2017
    Heidelberg
    Wittbrodt lab (at the Centre for Organismal Studies)
  • Cancer Research Uk Cambridge Institute
    Visiting Student
    Cancer Research Uk Cambridge Institute Sep 2016 - Jan 2017
    Cambridge, United Kingdom
    Hannon labon a CRUK-CI summer studentship
  • Helmholtz Munich
    Visiting Student
    Helmholtz Munich Apr 2015 - Jul 2015
    Neuherberg, München
    Desbordes lab
  • Johannes Kepler Universität Linz
    Bachelor Thesis
    Johannes Kepler Universität Linz Jul 2014 - Sep 2014
    Linz
    Pohl lab, supervised by Prof Andreas HornerInstitute of BiophysicsOverexpression, purification and reconstitution of various AQP4 protein variants into artificial lipid vesicles with subsequent stopped-flow analysis.Co-authored one publication: Positively charged residues at the channel mouth boost single-file water flowAndreas Horner*, Christine Siligan*, Alex Cornean and Peter Pohl*equal contributionhttps://doi.org/10.1039/C8FD00050F

Alex Cornean, Phd Education Details

Frequently Asked Questions about Alex Cornean, Phd

What company does Alex Cornean, Phd work for?

Alex Cornean, Phd works for Dataharmony

What is Alex Cornean, Phd's role at the current company?

Alex Cornean, Phd's current role is Co-founder & CEO @ DataHarmony, Director @ Databound Limited | Biomedical Scientist.

What schools did Alex Cornean, Phd attend?

Alex Cornean, Phd attended Heidelberg University, Heidelberg University, Universität Salzburg, Cardiff University / Prifysgol Caerdydd.

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