Alexander Howard Email & Phone Number

Littleton, CO, US

Cellerate CGT Consulting supports clients in development of cell and gene therapies. Drawing on extensive experience in development of T cell therapies Cellerate provides support in: process and analytical development, tech transfer, and cGMP manufacturing to support early through late phase biopharmaceutical CMC development.

Thousand Oaks, CA, US

• Lead and manage engineering team in design and execution of process development studies.
• Coordinated a team of 9 engineers and scientists in the design and execution of process development studies achieving tight timelines while focused on transparent communication of project status and potential risks to.
• Orchestrated the authorship of batch records, technical reports, and standard operating procedures for new products.
• Guided the engineering team's contributions to the integrated development of new products.
• Served as Process Development (PD) lead within the Chemistry, Manufacturing, and Controls (CMC) team for development of new cell therapy products and support of New Product Introduction (NPI).
• Cultivated supplier relationships for equipment and consumables.

Thousand Oaks, CA, US

• Champion continuous improvement in development of cell therapy production processes.
• Developed methods for the scale-up of T cell production processes in closed stirred-tank bioreactors.
• Specialized in cryopreservation, thaw, and dose preparation processes for cellular products.
• Led activities supporting tech transfer and manufacturing operations, including root cause investigations, laboratory studies, and staff training.
• Streamlined processes and developed studies by implementing statistically efficient design of experiments (DoE).
• Identified the design space and CQAs of cell therapy products that contributed to the world’s first commercially approved allogeneic T cell therapy.

Thousand Oaks, CA, US

• Perform process development and characterization studies and technology transfer activities.
• Execute process development and characterization studies and lead technology transfer activities.
• Innovate methods for cell production/cryopreservation, cell-based assays, and reagent preparation/qualification.
• Conduct maintenance and troubleshooting laboratory equipment, oversee service contracts.

Improved enzyme-based biosensors for a number of analytes in the bioprocessing field, including pharmaceuticals, biofuels, and food/beverage. Utilized design-of-experiments to improve sensor lifetime/performance, develop high-throughput screening assays, and automate sensor manufacturing.

Lakewood, Colorado, US

Diversified the capabilities of Terumo BCT's Quantum Cell Expansion System - including first successful expansion of human primary T cells. Contributed numerous engineering design verification/validation protocols and reports (controlled documents). Independently proposed and received internal funding for several research projects.

Madison, WI, US

I began my graduate career in Biomedical Engineering at UW-Madison in Fall 2011. In Spring, 2012, I joined Prof. Dave Beebe's lab, where I work on isolating rare cell types, proteins, and nucleic acids using a microfluidic technology entitled "IFAST"​ (immiscible filtration assisted by surface tension). My early work was part of a grant from the Bill and.

Fall 2010-Spring 2011:Worked one-on-one or in small groups tutoring athletes in organic chemistry, general chemistry, physics, and statics. I worked with athletes of diverse educational backgrounds to facilitate problem solving abilities, subject-specific knowledge, and enthusiasm for the sciences.

Spring 2010-Fall 2011: Creative Technology - Profs Janet DeGrazia, Charlie Nuttelman, Wendy Young, and Dan Schwartz.Attended lectures, facilitated learning, held office hours, administered exams, and graded papers for a topics-based science course for non-science majors.Spring 2011: Intro to Chemical Engineering: Prof. Charlie NuttelmanActed as guide and.

Spring-Summer 2008, Prof. Dan Schwartz Lab: Performed data analysis on adsorption/desorption of fatty acid molecules. Work was published in J Phys Chem C as "Single Molecule Observations of Fatty Acid Adsorption at the Silica/Water Interface:Activation Energy of Attachment"Fall 2008-Summer 2009: Prof Dhinakar Kompala LabMaintained Chinese hamster ovary.

Master Of Science (M.S.), Biomedical Engineering

Bachelor Of Science (B.S.), Chemical And Biological Engineering