Alexander Patch Email & Phone Number

San Diego, Ca, Us

United Kingdom

Brentford, Middlesex, Gb

Rancho Cordova , California, Us

• Developing, optimizing, and managing over 17 multimillion-dollar API / small molecule / drug substance manufacturing programs across product lifecycles for 9 of the world’s top biotech and pharmaceutical companies/customers so far. • Spearheaded matrix team through CEA project (capital expenditure authorization) for upgrading manufacturing capabilities with new, automated technology to support innovative processing and continuous improvement.• Leading cross-functional project teams, including members from production, quality, engineering, regulatory, and R&D, to successfully execute continuously evolving, complex programs within budget and on time.• Optimized program changeover efficiency by restructuring activity sequencing and improving capabilities, resulting in a 33% reduction in program start-up and product-to-product changeover times.• Establishing and maintaining strong relationships with key stakeholders, including customers, senior business leaders, regulatory agencies, and vendors, to support business objectives and add program value.• Conducting risk assessments and developing risk management plans for over 17 production processes across 9 facility sites including preparing and delivering presentations to senior management, auditors, and other stakeholders.• Leading 11+ Process Hazard Analyses (PHA), Hazard and Operability Analyses (HAZOP), and process safety management training to engineering and operations personnel. • Developing batch records, work instructions, and standard operating procedures (SOPs) for new equipment, manufacturing processes, and cleaning.• Conducting root cause analyses stemming from facility and process variances, followed by developing and implementing corrective and preventive actions (CAPAs) in response.

Rancho Cordova , California, Us

• Implemented a continuous improvement project on a process by automating limiting steps, which reduced material input cost by $50k per month and cut cycle time by 20%.• Directed operations activities and priorities in a fast-paced manufacturing environment, while also having investigated and troubleshot issues as the Lead Engineer and Person of Authority for plant operations overnight across 9 facility sites.• Acted as technical liaison between engineering, customers, partners, and project management in order to formulate technical solutions and support business initiatives related to scaled up processing.• Facilitated successful regulatory audits and inspections from both customers and the US FDA, ensuring compliance with quality standards and regulations, as well as gaining FDA approval on commercial products.

London, London, Gb

• Created company’s product formulation and resource database to centralize information and support process improvement• Forged new manufacturing partnerships by consulting with blenders to align expanding production capabilities and requirements• Supported the launch of consumer goods domestic and international business to consumer (B2C) supply chain, while expanding current business to business (B2B) network.• Calculated carbon emission reductions in manufacturing and supply chain in order to quantify environmental initiatives and secure green credentials• Analyzed supply chain data in order to increase visibility of key performance metrics

• Researched and tested various reaction pathways for fuel cells and stopping mechanisms in construction of a battery-powered mini-car to be used in competition

Seattle, Wa, Us

• Designed and executed coffee engagement plans for both customers and partners to share knowledge and drive enthusiasm for the core of the company’s products• Developed a powerful aptitude to communicate and show leadership with coworkers, resulting in a positive drive in workplace performance, positivity, interpersonal skills, and commitment

• Headed as Project Manager in developing strategy to solve 23andMe’s problem of balancing DNA data privacy concerns with innovative data usefulness by expanding 23andMe’s capabilities to address possibilities of preventive healthcare in the health and regulatory ecosystem • Designed plans of full-scale plant for 16 kiloton/yr. production of diethyl ether from catalytic dehydration of bio-ethanol to be used as a fuel additive for reducing transportation emissions • Developed scaled design for Alpha-Cyclodextrin production process to be used for a new method of gold extraction, including economic, environmental, and social assessment • Created process model and PID control system designed to regulate the behavior of a non-isothermal CSTR chemical reactor in response to set point changes and external disturbances

Davis, California, Us

• Used computational chemistry and molecular dynamics to study surface reactions between frozen water and acids in the atmosphere in order to understand its relation to ozone depletion • Developed problem solving, Linux, and computational chemistry skills

Rancho Cordova , California, Us

• Led four-month long project to design, source, construct, install, and control the R&D department’s first continuous distillation skid used to distill and concentrate various solutions critical to the drug development phase. • Utilized HPLC and Gas Chromatography technology to analyze samples in continuing drug research

Bachelor'S Degree, Chemical Engineering

Education record