Alexandra Doolittle Email & Phone Number

Charleston, South Carolina Metropolitan Area

- Deliver comprehensive project administration support, including maintaining, reviewing, and communicating project progress, ensuring smooth and efficient project operations.- Proactively ensure the development and adherence to project timelines to ensure timely completion of deliverables.- Support the development of agendas and prepare project reports, facilitating effective communication and providing stakeholders with clear updates on project status.

San Francisco, California

- Conducted CRISPR Screens, Viral Production, Plaque, and Toxicity Assays on infected cells with Coronavirus 229E, SARS CoV2, Salmonella, and MuNoV, contributing to the development of effective treatments and prevention strategies for infectious diseases.- Regularly completed data analysis and presented findings, facilitating data-driven decision making and progress in research projects.- Maintained clear and concise documentation of experimental protocols and results, ensuring reproducibility and facilitating future research efforts.

Greater Philadelphia Area

- Provided consultation and support in the drug design process at RiboNova Inc., leveraging PyMOL to analyze molecular structures and optimize drug candidates.- Effectively communicated challenges, progress, and findings to management.- Conducted comprehensive analysis of prior art for company patents, identifying potential infringements.- Visited Brookhaven Laboratories’ Synchotron. Worked with Engineers to visualize/characterize our target through Small Angle Scattering

- Conducted research on intervertebral disc degeneration at Thomas Jefferson University, contributing to the advancement of knowledge in the field.- Presented research findings to the graduate program, effectively communicating complex scientific concepts in a clear and concise manner.- Contributed to four peer-reviewed scientific papers.- Received a Best Poster Award at the ORS PSRS 4th International Spine Research Symposium for “Arp2/3 Promotes the Nucleus Pulposus Cellular Response to Osmotic Stress” Doolittle AC, Shappiro IM, Risbud, MV.

Wynewood, Pa

-Played a role in the startup of RiboNova Inc., a company specializing in rare disease diagnostics and therapeutics, contributing to the establishment and growth of the organization.- Gained valuable research experience in experimental design, tissue culture, molecular biology techniques, and molecular modeling.- Collaborated on the design and modeling of small molecular drugs using PyMOL, contributing to the development of potential therapeutic solutions.-Successfully managed and troubleshooted multiple ongoing experiments corresponding to various projects, ensuring smooth progress and timely completion.

- Conducted research in the field of regenerative medicine, specifically focusing on designing and producing hydrogels for use as stem cell scaffolds in bone defect repair.- Utilized solid phase peptide synthesis to create self-assembling peptides that leverage the synergistic effects of RGDs and PHSRN to differentiate MSCs to osteoblasts.

Philadelphia, Pa

- Conducted extensive prior art research on patent W02012064675A3: Nuclions and Ribocapsids.- Demonstrated strong attention to detail and meticulous research skills in the analysis of complex scientific information.

West Chester, Pa

- Developed and optimized protocols on the Flow Cytometer for the detection of MSCs and Osteoblasts in Bone Marrow Aspirate (BMA).- Conducted analysis of steroids for their osteoblast differentiation potential and developed protocols for testing their effectiveness .

Lawrenceville, Nj

-Contributed to the development of a functional assay to test the reduction of IL-2 upon cell treatment with a rheumatoid arthritis drug, utilizing Luminex and Flow Cytometer techniques.

B.A., Biological Engineering

Activities and Societies: Alpha Phi, ArcTan - Red Cross, Undergraduate Association Athletic Board

Executive Mba, Business Administration And Management, General

Master Of Science (M.Sc.), Biomedical/Medical Engineering, Honors

Thesis: The Synergistic Effects of RGDS and PHSRN Fixed on Polymer Scaffolds to Induce Osteogenesis Worked on the creation of hydrogels.