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Alexandra Klinger is listed as Founder | Principle Scientist at Decipher Hydro, based in Greater Philadelphia, United States, United States. AeroLeads shows a matched LinkedIn profile for Alexandra Klinger.
Alexandra Klinger previously worked as Founding Principle Scientist at Decipher Hydro and Postdoctoral Fellow at University Of Pennsylvania. Alexandra Klinger holds Ph.D., Biophysics from University Of Virginia.
At DecipherHydro, I lead collaborative efforts using a high resolution oxidative footprinting approach coupled with LC/MS-MS to quantitatively characterize both structurally and dynamically intrinsically disordered proteins and protein regions at the single amino acid level. Currently we are focused on toxic amyloid oligomers -- a promising therapeutic target in Alzheimer Disease.Biophysical and Biochemical characterization (LC/MS-MS, FTIR, UV-Vis, Fluorescence), Thermodynamics, Modeling and Simulation, Protein Characterization, Ligand Binding, and Allostery, High-throughput screening, Hit to Lead, Assay development,
Listed skills include Biochemistry, Biophysics, Fluorescence, Drug Discovery, and 28 others.
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Greater Philadelphia Area
Developing hydroxyl radical labeling coupled with LC/MS-MS to characterize intrinsically disordered proteins using individual side-chain surface accessibilities.
Philadelphia, Pennsylvania, United States
Biochemistry and Biophysics, Dr. Paul AxelsenDeveloped single amino acid resolution quantitative hydroxyl radical footprinting LC/MS-MS to elucidate and publish Alzheimer Disease relevant amyloid fibril structure.
Established biophysical mathematical models to explore extracellular matrix effects on endothelial cell networking and smooth muscle cell motility developing diagnostic tools for Pulmonary Arterial Hypertension for (PAH).
Screening Group Leader, Cranbury NJ site
Contributed to the group’s investigations into the molecular mechanisms of hemoglobin cooperativity involving a wide range of quantitative spectroscopic and thermodynamic methods.
Thesis Advisor: Dr. Mark S. Braiman Thesis Title: Kinetic Analysis of Membrane Systems Using Fourier Transform Infrared Spectroscopy
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Alexandra Klinger works for Decipher Hydro.
Alexandra Klinger is listed as Founder | Principle Scientist at Decipher Hydro.
Alexandra Klinger is based in Greater Philadelphia, United States, United States while working with Decipher Hydro.
Alexandra Klinger has worked for Decipher Hydro, University Of Pennsylvania, Johnson & Johnson, 3-Dimensional Pharmaceuticals, and Washington University.
You can use AeroLeads to view verified contact signals for Alexandra Klinger at Decipher Hydro, including work email, phone, and LinkedIn data when available.
Alexandra Klinger holds Ph.D., Biophysics from University Of Virginia.
Alexandra Klinger is listed with skills including Biochemistry, Biophysics, Fluorescence, Drug Discovery, Cell, Protein Chemistry, Spectroscopy, and Assay Development.
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