Alex Ritter Email & Phone Number

• Thoughtful, creative immunologist/cell biologist with 12 years of experience investigating cytotoxic T cell function through advanced microscopy techniques. • My research applies quantitative imaging approaches to visualize and measure effects of perturbation on biological systems with a special focus on live cell imaging of cytotoxic T lymphocyte (CTL) killing of cancer cells. • Extensive experience in data acquisition and analysis with a broad range of cutting-edge imaging modalities including live cell imaging techniques (Lattice light sheet, spinning disc microscopy, TIRF imaging, live cell super-resolution, and widefield fluorescence) and fixed standard- and super-resolution microscopy (SIM, PALM). I know what imaging techniques are appropriate to answer specific biological questions. • Developed quantitative approach to measure instantaneous killing of targets by T cells in real time following therapeutic intervention or genetic perturbation in both 2D and 3D tumor cultures. • Identified novel mechanism by which cancer cells resist killing by cytotoxic T cells. • Established quantitative imaging techniques to monitor subcellular dynamics of organelles and cytoskeleton in CTLs destroying cancer cells.• Captured and produced quality images and videos that are widely used to demonstrate cytotoxic T cell activity in scientific talks, textbooks, online, and on television. • Maintain connections with a wide network of microscopy experts at top academic institutions to share knowledge and collaborate. • Glass worker with 4 years of experience. Recent projects include modeling biological systems with hot glass.

Listed skills include Molecular Biology, Cell Culture, Research, Data Analysis, and 11 others.