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Senior drug hunter with 30+ years of experience bringing small molecule drug candidates against multiple target classes and therapeutic areas from discovery to clinical trials. Passionate about building and developing teams, and a culture where all scientists are motivated and have opportunities to innovate. Demonstrated scientific and organizational leadership in the discovery and development of innovative drugs. Scientific expert with over 65 peer reviewed articles, presentations, and patent filings.
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Chief Scientific OfficerTesseract Medicines Jul 2023 - PresentNewton, Massachusetts, Us -
Exceutive Vice President, Small Molecule Drug DiscoveryIkena Oncology Jun 2022 - Jul 2023Boston, Massachusetts, Us -
Senior Vice President, Small Molecule Drug DiscoveryIkena Oncology Dec 2017 - Jun 2022Boston, Massachusetts, Us
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Consultant/Advisor, Drug Discovery And ChemistryIkena Oncology Dec 2016 - Nov 2017Boston, Massachusetts, Us
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Vice President, ChemistryInfinity Pharmaceuticals Sep 2012 - Aug 2016Cambridge, Massachusetts, UsActively guided drug discovery and drug substance efforts at Infinity, with direct responsibilities for medicinal chemistry, process chemistry, and biochemistry. Worked with cross functional colleagues to define drug discovery and development strategies, priorities, and goals. -
Senior Director, ChemistryInfinity Pharmaceuticals Mar 2009 - Sep 2012Cambridge, Massachusetts, UsManaged and guided a team of 25 medicinal chemists, process chemists, and chemical engineer across multiple discovery and process development programs.
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Director, ChemistryInfinity Pharmaceuticals Sep 2005 - Mar 2009Cambridge, Massachusetts, UsAs the head of chemistry at Infinity, responsible for managing and developing a talented team of 22 medicinal and process chemists.
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Principal ScientistInfinity Pharmaceuticals May 2004 - Sep 2005Cambridge, Massachusetts, UsContributed to hedgehog, Bcl-2, and FAAH lead optimization programs, and managed a team of 9 medicinal and computational chemists.
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Associate Director Of ChemistrySyntonix Pharmaceuticals Oct 2002 - Apr 2004UsWorked with and managed a team of scientists in the design and synthesis of peptide and small molecule therapeutics conjugated to Fc, and on the design and synthesis of inhibitors of the FcRN - IgG interaction. -
Director Of ChemistryMds Proteomics Oct 2001 - Oct 2002Contributed to a phosphoproteomics platform and initiated efforts on the identification of EphB4 inhibitors. -
Senior Scientist IiMillennium Pharmaceuticals Jan 2000 - Oct 2001Cambridge, Ma, UsBecame a Millennium employee upon their acquisition of Leukosite, which had just prior acquired ProScript. At Millennium, I continued to lead the IkB kinase lead optimization program and managed a talented team of medicinal chemists. -
Senior ScientistProscript Jan 1997 - Jan 2000Contributed to IkB kinase (IKK), Ras endoprotease, and matrix metaloprotease-3 inhibitor programs.
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Scientist I, Scientist IiBiogen Jun 1993 - Jan 1997Cambridge, Ma, UsOne of the first medicinal chemists to join Biogen's small molecule drug discovery group. Contributed to the design and synthesis of small molecule integrin antagonists (a4b1 selective and a4b7 selective), ultimately identifying Bio-1211 as a clinical candidate for asthma. -
Postdoctoral AssociateMassachusetts Institute Of Technology (Mit) Jun 1992 - Jun 1993Cambridge, Ma, UsWorked in Prof. Satoru Masamune's research lab.
Alfredo Castro Skills
Alfredo Castro Education Details
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Dartmouth CollegeOrganic Chemistry -
Clark UniversityChemistry
Frequently Asked Questions about Alfredo Castro
What company does Alfredo Castro work for?
Alfredo Castro works for Tesseract Medicines
What is Alfredo Castro's role at the current company?
Alfredo Castro's current role is CSO, Tesseract Medicines.
What is Alfredo Castro's email address?
Alfredo Castro's email address is ac****@****ail.com
What schools did Alfredo Castro attend?
Alfredo Castro attended Dartmouth College, Clark University.
What skills is Alfredo Castro known for?
Alfredo Castro has skills like Pharmaceutical Industry, Medicinal Chemistry, Oncology, Chemistry, Clinical Development, Life Sciences, Drug Discovery, Biotechnology, Drug Development, Pharmacology, Lifesciences, Regulatory Submissions.
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