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Pregnancy is a wonderful but dynamic and challenging time where we are starting to understand that the time from conception through the early years has a profound impact on an individual's health. I want to improve early-life health so that children are all able to make the best of life.Sometimes diseases are only unmasked by pregnancy due to the high levels of pregnancy hormones. Through accurate diagnosis and testing new treatments for women who develop diseases of pregnancy, we can improve women's health during pregnancy and also that of the babies'.My current work includes: - Investigating the role of fat and circulating fats in the development of the gestational disease intrahepatic cholestasis of pregnancy (ICP) at Imperial College London. - Evaluating clinical results of a trial investigating a potential new therapeutic for gestational diabetes and looking at treatment response in dynamic metabolic parameters. - Co-investigating early-stage potential treatments for ICP.My previous work has altered the Royal College of Obstetrician's Greentop Guidelines for diagnosis of ICP to include non-fasting blood bile acids as a more accurate reflection of disease severity. This work was particularly important as we also evaluated ethnicity-specific blood bile acid ranges, ensuring that the normal ranges were inclusive so that the disease can be accurately diagnosed. I have also been involved in numerous grant applications, ethical research applications, project management and report writing.Additional duties:- Lab management - Mentoring of junior colleagues- Human Tissue Act Named Person to ensure compliance of storage and use of human samples- Sustainability Officer working to improve sustainability within the lab through improving recycling policies and promoting awareness of efficient energy usage and reducing waste production.
Imperial College London
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Postdoctoral Research In Women And Children'S HealthImperial College LondonLondon, England, Gb -
Postdoctoral Research In Women And Children'S HealthImperial College London Aug 2023 - PresentInvestigating how gestational diseases impact women and their baby's health.-Analysis of clinical trial data investigating dynamic metabolic hormone responses to a potential new therapy for gestational diabetes.-Early-stage investigation into a potential therapy for intrahepatic cholestasis of pregnancy.- Investigation of how visceral and subcutaneous fat changes in response to high blood bile acids in intrahepatic cholestasis of pregnancy. -
Postdoctoral ResearcherKing'S College London Feb 2018 - Aug 2023Exploring the clinical pathophysiology of intrahepatic cholestasis of pregnancy and how the clinical diagnostic threshold for serum bile acids needs to be performed when women are not fasting to give an accurate diagnosis of severity. I am also involved in trial design to investigate a potential new therapeutic for gestational diabetes, alongside evaluating treatment influence on metabolic changes in response to a standardised meal. -
PhdUcl Jan 2013 - Feb 2018University College LondonAssessing mitochondrial dysfunction in patient cell lines, and understanding how the mitochondria of cancer cells adapt to nutrient starvation.
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Frequently Asked Questions about Alice Mitchell
What company does Alice Mitchell work for?
Alice Mitchell works for Imperial College London
What is Alice Mitchell's role at the current company?
Alice Mitchell's current role is Postdoctoral Research in Women and Children's Health.
What is Alice Mitchell's email address?
Alice Mitchell's email address is al****@****k.ac.uk
What schools did Alice Mitchell attend?
Alice Mitchell attended Ucl, Imperial College London.
What skills is Alice Mitchell known for?
Alice Mitchell has skills like Research, Science, Molecular Biology, Biochemistry, Cell Culture, Data Analysis, Life Sciences, Statistics, Pcr, Cell Biology, Team Leadership, Non Profit Volunteering.
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Alice Mitchell
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Alice Mitchell
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Alice Mitchell
United Kingdom
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