Alin Goroh Email & Phone Number

Regulon is an oncology-focused drug delivery company leveraging proprietary and differentiated tumor-targeting nanotechnology to develop improved branded versions of leading chemotherapy drugs. Regulon’s lead product, Lipoplatin for pancreatic cancer (same drug under the name Nanoplatin for non-small cell lung cancer, NSCLC), is a liposomally encapsulated cisplatin nanoparticle. Cisplatin is the most widely-used chemotherapy drug, the gold standard for epithelial malignancies with applications to over 50% of human cancers. Lipoplatin nanoparticles, loaded with cisplatin are uptaken by tumors and metastases (10 to 200-fold higher than normal tissue) by leaking through the compromised endothelium of tumor vasculature sprouted during neoangiogenesis, a process known as extravasation, and by the avidity of tumors for nutrients with Lipoplatin disguised as a nutrient with its lipid shell. Moreover, Lipoplatin nanoparticles fuse with the cell membrane thus emptying their toxic payload directly inside the cytoplasm of the cell bypassing the cell membrane barrier often impermeable by cisplatin especially in resistant tumors.

Listed skills include Petroleum, Стратегия Ведения Бизнеса, Ведение Переговоров, Бизнес Планирование, and 2 others.

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  Universitatea Agrară De Stat Din Moldova

  Economics