Alyssa J. Miller, Phd

Alyssa J. Miller, Phd Email and Phone Number

Associate Director at Conception @ Conception
Alyssa J. Miller, Phd's Location
Berkeley, California, United States, United States
Alyssa J. Miller, Phd's Contact Details

Alyssa J. Miller, Phd personal email

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About Alyssa J. Miller, Phd

Scientist and team leader with expertise in stem cell biology, genetics, developmental biology, 3D tissue engineering and organoids, with a focus on cell fate decisions. I am passionate about developing people and ideas to leverage stem cell biology to improve human lives.https://twitter.com/_Alyssa_J_

Alyssa J. Miller, Phd's Current Company Details
Conception

Conception

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Associate Director at Conception
Alyssa J. Miller, Phd Work Experience Details
  • Conception
    Associate Director, Head Of Cell And Tissue Engineering
    Conception Jan 2023 - Present
    Berkeley, California, Us
    I lead multiple multidisciplinary teams of scientists to develop ovarian organoids and in other vitro tissue systems to generate viable human eggs from pluripotent stem cells.Specifically, I provide scientific leadership and direction for 2 core teams within our organization. This work includes high level strategy development and project planning to improve efficiency of experimental designs across teams and analysis and integration of data company wide to decide next steps to achieve long term goals. I manage a diverse group of researchers, including team leads and scientists from associate to senior level, and provide active mentorship tailed to individuals to help them reach their scientific and professional potential.
  • Conception
    Associate Director, Organoid Team Lead
    Conception Sep 2021 - Dec 2022
    Berkeley, California, Us
    I built and managed a team of researchers focused on generating 3-dimensional tissue structures to facilitate germ cell development and follicle assembly and growth in vitro. I led this team to deliver two milestones critical for proof of concept 8 and 4 months ahead of schedule. While in this role, I also led our cell production pipeline, facilitating a 10x scale up in production in under 6 months.In this role I have mentored 13 researchers ranging from research associate, scientist and senior scientist levels, routinely managing a team size between 5-10 direct reports.
  • Conception
    Scientist
    Conception Mar 2021 - Sep 2021
    Berkeley, California, Us
    I work as a part of a multidisciplinary team generating viable human eggs from human pluripotent stem cells.During my time in this role, I developed a project to direct the differentiation of iPSC to a specific cell state and optimized related in vitro tissue formation. I developed assays to characterize cells including IHC, FLOW and FACS panels, and collaborated with computational biologists to generate, process and interpret bulk and single cell RNA-seq datasets. I led the scientific direction for how to benchmark these cells against in vivo counterparts. I also gained experience generating reporter cell lines using lentiviruses and CRISPR editing.
  • University Of Pennsylvania School Of Medicine
    Postdoctoral Research Fellow
    University Of Pennsylvania School Of Medicine Oct 2019 - Mar 2021
    Pa, Us
    During my postdoc, I studied the role of epigenetic modifications during stem cell differentiation during human development and disease in the laboratory of Dr. Ken Zaret. The goal of my work was to understand how heterochromatin dynamics allow functional maturation of human insulin-producing pancreatic beta cells during normal development, and to use this knowledge to develop more mature beta cells from human pluripotent stem cells in a dish. Long term, this work aims to improve clinical treatment options for diabetes by improving the quality and quantity of beta cells for transplantation and by identifying therapeutic targets to prevent or reverse beta cell de-differentiation in diabetics.
  • University Of Michigan Medical School
    Graduate Student
    University Of Michigan Medical School Sep 2014 - Sep 2019
    Ann Arbor, Mi, Us
    Ph.D. Candidate in the graduate program for cellular and molecular biology in the laboratory of Dr. Jason Spence. My thesis work focused on understanding cell fate decisions during human lung development and using this information to generate in vitro models of lung development and disease from human pluripotent stem cells.
  • University Of Michigan Office Of Technology Transfer
    Technology Transfer Fellow
    University Of Michigan Office Of Technology Transfer Jun 2017 - Jun 2018
    I used my expertise in science and technology to analyze and interpret academic invention disclosures. Specifically, I produced concise reports for a non-science professional audience that are used in patent licensing decisions. Reports include invention summaries, customer segments, competition landscapes, market analysis and prior art analysis. My analysis has covered inventions from a wide variety of research disciplines, including research tools, medical devices, diagnostics and software.
  • Massachusetts General Hospital
    Lab Manager / Research Technician
    Massachusetts General Hospital Jun 2012 - Aug 2014
    Boston, Ma, Us
    Assisting with Pulmonary research focusing on the use of high resolution, near-infrared optical imaging techniques to better understand and diagnose lung diseases.Managed a clinical trial related to the use of a medical device during thoracic surgery. This included all IRB protocols and reviews, management of participant recruitment and properly storing all study related documents. Managed all animal protocol designs and approvals through IACUC.
  • Massachusetts General Hospital
    Pulmonary Function Technician
    Massachusetts General Hospital May 2011 - Aug 2012
    Boston, Ma, Us
    Worked in a clinical setting assisting patients to perform breathing maneuvers used to monitor and diagnose pulmonary diseases.
  • Hepregen Corporation
    Product Development Intern
    Hepregen Corporation May 2010 - Aug 2010
    Medford, Massachusetts, Us
    Worked as a Product Development Intern to assist in the manufacture of micro-patterned liver co-culture plates. Collected and analyzed functional data of cultures using ELISA competitive binding assays, PCR, and staining techniques (rat and human platforms).
  • Boston University
    Undergraduate Research Assistant
    Boston University Sep 2008 - May 2009
    Boston, Ma, Us
    Assisted in the research and study of animal behavior and sensory biology of the North American Lobster.Developed an individual research project exploring the localization of mechano- and chemo receptors in lobster antennules.

Alyssa J. Miller, Phd Skills

Research Statistics Neuroscience Cell Culture Pcr Programming Python Sql Stem Cell Research Molecular Genetics Biochemistry Science

Alyssa J. Miller, Phd Education Details

  • University Of Michigan
    University Of Michigan
    Cellular And Molecular Biology
  • Boston University
    Boston University
    German
  • Guilford College
    Guilford College
    High School Diploma - Early College At Guilford

Frequently Asked Questions about Alyssa J. Miller, Phd

What company does Alyssa J. Miller, Phd work for?

Alyssa J. Miller, Phd works for Conception

What is Alyssa J. Miller, Phd's role at the current company?

Alyssa J. Miller, Phd's current role is Associate Director at Conception.

What is Alyssa J. Miller, Phd's email address?

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What is Alyssa J. Miller, Phd's direct phone number?

Alyssa J. Miller, Phd's direct phone number is (734)-764*****

What schools did Alyssa J. Miller, Phd attend?

Alyssa J. Miller, Phd attended University Of Michigan, Boston University, Guilford College.

What skills is Alyssa J. Miller, Phd known for?

Alyssa J. Miller, Phd has skills like Research, Statistics, Neuroscience, Cell Culture, Pcr, Programming, Python, Sql, Stem Cell Research, Molecular Genetics, Biochemistry, Science.

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