Covid-19 Vaccine Project Management Analytical Technical transfer and Analytical Supply Chain

Drive transformation to achieve integrated end-to-end, lean Supply Chain that is agile and flexible. Reduce long lead times and high inventory to lower the working capital.Drive business results with routine, collaborative, and cross-functional engagement across the value stream.

Analytical lead on transfer teams: managing method robustness, transfer, validation, and process performance qualification readiness activities. Overall QC demand planning.

Analytical lead on transfer teams: managing method robustness, transfer, validation, and process performance qualification readiness activities. Overall QC demand planning.

• Analytical method transfer, qualification and validation.• Assay development for potency assays and kinetic characterization of biotherapeutics on label-free, SPR-based instruments.

• Tested Alzheimer's disease therapeutic agents, including cell-free, in vitro, and in vivo systems. Conducted techniques: mouse CSF collection and drug administration (IV in mouse tail vein, I.P., and intranasal), western blotting, epitope mapping, and cell culture. • Developed assays for testing efficacy of A-beta lowering agents: Human A-beta 40 and 42 ELISA (Horikoshi et. al., 2004), Murine A-beta 40 and 42 ELISA (Hoe, et. al., 2005; Horikoshi, et. al., 2004), Human A-beta 40 and 42 TR-FRET assays, and beta-secretase enzyme inhibition

Proteomics: building DNA plasmids, ligation, bacterial and yeast transfection and culture, gel electrophoresis, PCR, protein purification, and mass spectrometry