Amanda Degraw, Ms, Phd, Dabt Email & Phone Number

Saint Paul, MN, US

Mansfield, MA, US

Abbott Park, Illinois, US

- Conduct toxicological risk assessments on medical device/component extractable and leachable studies.- Collaborate with analytical chemistry team in design of extractable and leachable characterization studies, review testing protocols, and review reports.- Perform compositional profiling based on medical device composition to assess toxicological risk.

Raynham, MA, US

Provided technical support for toxicology and biocompatibility processes to meet business objectives. Responsible for conducting toxicological risk assessments based on data derived from extractables and leachables studies, in support for new product development and sustaining activities, as well as in support of global regulatory submissions. Oversaw the.

Raynham, MA, US

Conducted biocompatibility assessments and biocompatibility evaluation plans and reports in compliance with applicable standards and FDA/ISO guidance documents within a risk-based framework. Responsible for the oversight of bioassay and extractable and leachable testing conducted at contract research organizations.

Abbott Park, Illinois, US

Responsible for the design and execution of post-market clinical evaluations of cardiac mapping catheters in collaboration with key opinion leaders in cardiac electrophysiology; determined study endpoints, authored protocols, presented study design to site directors, conducted preliminary data analysis at designated study checkpoints, and authored study.

Abbott Park, Illinois, US

- Analytical method development chemist. Subject matter expert for biological chemistry techniques, high-pressure liquid chromatography, and mass spectrometry. - Extractables and leachables testing subject matter expert. Well versed in the design and execution of studies for medical devices and their packaging materials. - Extensive knowledge in the.

Minneapolis, MN, US

- Advised on the design and supported the execution of extractable/leachable characterization testing of medical devices and pharmaceutical packaging.- Developed and validated methods for the characterization of pharmaceutical and combination products; projects included HPLC analysis for drug purity and stability characterization, drug dissolution methods.

Minneapolis, MN, US

- Trained in polymer-small molecule formulation techniques.- Created a novel biodegradable polymer containing a near-IR emitting fluorophore. Used to create microspheres to study the clearance in situ upon injection in the synovial fluid of a rat knee. - Developed HPLC and LC-MS methods for the analysis of polymer-small molecule formulations for material.

Minneapolis And St. Paul, Minnesota, US

- Thesis Title: Applications of substrate analogues for studies of prenyltransferase enzymes- Developed and characterized a protein bioconjugation technique based on the natural post-translational protein modification, prenylation. Applied technique towards the in situ evaluation of protein prenylation using HPLC, SDS-PAGE, and mass spectrometry.- Created.

- Responsible for the care of hospitalized patients including feeding, medicating, and performance of physical therapy as needed.- Assist in routine and pre-surgical exams, sample collection, and surgical procedures.

St. Paul, MN, US

Thesis Title: Solid-phase peptide synthesis of Kasumigamide, a novel anti-algal compound

Master Of Science (M.S.), Pharmacology And Toxicology

Doctor Of Philosophy (Ph.D.), Chemical Biology (Chemistry)

Bachelor Of Arts (B.A.), Chemistry