. Study of the process of molecular aggregation. Research focused on amyloid protein aggregates (related, e.g., to Alzheimer disease) directly in humantissue, ex vivo and in vitro. Ex vivo material preparation for analyses. Morphological analyses performed using the Atomic Force Microscope. Kinetic analyses performed using the Spectrofluorometer. Particles dimension analyses performed using the Dynamic Light Scattering. Laboratory managing. Annual reporting to… Show more . Study of the process of molecular aggregation. Research focused on amyloid protein aggregates (related, e.g., to Alzheimer disease) directly in humantissue, ex vivo and in vitro. Ex vivo material preparation for analyses. Morphological analyses performed using the Atomic Force Microscope. Kinetic analyses performed using the Spectrofluorometer. Particles dimension analyses performed using the Dynamic Light Scattering. Laboratory managing. Annual reporting to the Scientific Project Committee Show less

. Study of the effects of physical-chemical risks factor on the amyloid aggregation process (in vitro). Self-assembly of PAH and, in general, supramolecular aggregates on nanopatterned HOPG. Procedure issuing. Protein handling and solutions preparation. Morphological analyses performed using the Atomic Force Microscope. Kinetic analyses performed using the Spectrofluorometer. Particles dimension analyses performed using the Dynamic Light Scattering. Structure probing… Show more . Study of the effects of physical-chemical risks factor on the amyloid aggregation process (in vitro). Self-assembly of PAH and, in general, supramolecular aggregates on nanopatterned HOPG. Procedure issuing. Protein handling and solutions preparation. Morphological analyses performed using the Atomic Force Microscope. Kinetic analyses performed using the Spectrofluorometer. Particles dimension analyses performed using the Dynamic Light Scattering. Structure probing by SAXS technique (DESY Synchrotron, Hamburg). Reference, for other groups, for AFM analyses (e.g.: composed metallic/organic/biologic systems). Annual reporting to the Academic Committee Show less

. Study of relationship between structure and environmental factors on the protein and peptidesmisfolding-aggregation process. Use of Atomic Force Microscopy for protein aggregation study. Investigation of HOPG nanopatterning during interaction with aqueous macromolecular solutions

. Syntheses of crystal of know and new proteins for 3D structure reconstruction. Schedule of protein solutions testing and their preparation. Setting of the automatic wide-range solution investigation robot. Pre-analysis and selection of the synthesised protein crystals