Amber Pospistle Email & Phone Number

Huntersville, Nc, Us

Cambridge, Massachusetts, United States

- Computational biology intern in the Getz Lab, which focuses on computational cancer genomics- Continuing as an intern through Spring 2025- Benchmarking Tonly2, a statistical method that predicts whether a mutation is somatic or germline from tumor-only samples- Optimization of Tonly2 including implementation of multiprocessing- Presented poster and oral presentation at the Broad Institute- Results will be included in a manuscript to be submitted in Winter or Spring 2023/2024

- Undergraduate research assistant in the lab of Forest Agostinelli- Deep learning model to predict protein-ligand binding affinity

- Share my experience applying to and participating in national fellowships at outreach events- Present about national fellowship opportunities to first-year students - Meet with students interested in national fellowships for 1 on 1 coffee chats

- Undergraduate researcher in the Cai Lab in the Arnold School of Public Health- Conducted literature review and proposed my own project - Chose appropriate methodology for the project and completed all analyses independently- Currently preparing a first-author manuscript with my findings - Abstract award at the National Big Data Health Science Conference

New York, New York, United States

- Participant in the Computational Biology Summer Program hosted by Memorial Sloan Kettering Cancer Center, Weill Cornell, and Rockefeller University - Worked independently on a computational immuno-oncology research project - Attended journal clubs and lab meetings - Presented at Memorial Sloan Kettering and the Stamps Scholars National Convention- Manuscript expected to be submitted in 2023

Durham, North Carolina, United States

- Took courses in Introduction to Computational Science, Computational Biology/Bioinformatics, Computational Medicinal Chemistry, Organic Chemistry, and Special Topics in Pharmacy- Performed computational pharmacokinetics predictions, pharmacokinetic modeling using differential equations, metabolism studies, docking studies, and pharmacodynamics studies for neuraminidase inhibitors- Developed a differential equations model in STELLA using differential equations and parameters from literature to model immune cell populations and tumor size over time after treatment with dendritic cell vaccines, T-cell adoptive therapy, chemotherapy, and combined treatments- Performed a Genome-Wide Association Study to identify quantitative trait loci (genomic regions associated with variation in a phenotypic trait) associated with plaque buildup, cholesterol, triglycerides, and glucose in mice fed a Western (high-fat) and normal diet

Pine Lake Preparatory

- Oversee team operations including fundraising, sponsorship, awards writing, public relations, community outreach, and finance.- Work directly with team captain, engineering director, operations subteam leads, scheduling/project management lead, coach and mentors.- Train operations subteam leads and team members.- Coordinate STEM outreach events at local community centers or events

Pine Lake Preparatory

-Developed and led the project management subteam upon identifying need - Collaborated with several leads and teams to develop a schedule and project management platform- Provided project management and scheduling training for team members

Pine Lake Preparatory

- Participated on the electrical team as well as strategy team during competitions.- Participated in engaging community members in STEM activities and volunteering at robotics competitions for elementary and middle school students.

- Participated in a internship with UNC Chapel Hill School of Medicine (Hoadley Lab) for 30 hours per week. - Computational biology project focused on breast cancer and the tumor microenvironment.- Attended lab meetings and a professional conference. - Performed data analysis using R and Microsoft Excel.

- Participated in a internship with East Carolina University Department of Biology (Issa Lab) on a neuroscience research project for 35 hours per week.- Performed polymerase chain reaction (PCR), gel electrophoresis, and other genetic lab techniques.- Presented research project at North Carolina Undergraduate Research and Creativity Symposium at Duke University, NC.

Computational Biology

Activities and Societies: Chi Alpha, Gamecocks Aiding Refugees in Columbia, Neuroscience Club, Omega Phi Alpha National Service Sorority.

Ncssm Online

NCSSM Online is a competitive, application-based, supplemental, two-year sequenced honors program for juniors and seniors in North Carolina.

High School Diploma

Activities and Societies: Team SPORK, EPIC/VEX Robotics, Key Club, Aquaponics, National Honor Society, Spanish Honor Society, Mu Alpha Theta