Amesh Sarecha Email & Phone Number

New York, Ny, Us

New York City Metropolitan Area

Ozcan Lab, Department Of Medicine, Division Of Molecular Medicine

• Spearheaded critical research projects as a key member of the laboratory of Dr. Lale Ozcan at Columbia University, conducting extensive experiments on mice and cells and utilizing techniques such as Western Blotting, Q-PCR, and ELISA assays to uncover novel insights into the molecular mechanisms underlying obesity-related Type II Diabetes.• Drove breakthrough findings in the field of diabetes research by publishing into high-impact factor research journals detailing the previously unidentified roles of Epac2 and its downstream mediator, Rap1a, in regulating hepatic glucose metabolism, as well as elucidating the mechanisms through which hepatocyte Rap1a contributes to the regulation of gluconeogenesis via insulin-sensitive gluconeogenic transcription factors Foxo1,3,4.• Demonstrated a deep understanding of the intersection of medicine and research, regularly participating in large divisional meetings and journal clubs and showcasing a strong drive and curiosity in the lab, leading to the development of innovative experimental approaches and the execution of complex surgical procedures on mice, cementing a reputation as as a highly respected and sought-after researcher among peers and medical professionals alike.

Arancio Lab, Department Of Pathology And Cell Biology

• Spearheaded research in Dr. Arancio's laboratory to investigate the cellular and molecular mechanisms underlying long-lasting changes of synaptic function in both normal, healthy brains and in Alzheimer's disease (AD) affected brains, with a focus on the role of oligomeric proteins, including amyloid-β (Aβ) peptides and tau, in interfering with memory formation and regulation of hippocampal long-term potentiation (LTP).• Conducted in vitro acetylation assays to detect the acetylation of the lysine residues 18 and 27 on histone H3 for the development and testing of a compound for the treatment of Alzheimer's disease that activates HATs p300, CBP, and PCAF, leading to memory amelioration. Calculated EC50 for activators or IC50 for inhibitors and analyzed the Structure-Activity Relationships (SARs) of the chemical structures to determine the chemical group responsible for evoking the biological effect.• Collaborated with a team of researchers to investigate the role of gene activation and silencing, post-translational mechanisms, channel opening, intracellular calcium transients, and changes in transmitter release machinery in basal synaptic transmission and synaptic plasticity. Presented research findings in laboratory meetings and contributed to the preparation of manuscripts for peer-reviewed scientific journals.

• Demonstrated mastery of diverse subject matters and teaching techniques, seamlessly adapting to different curricula and classrooms while maintaining high engagement and academic rigor. Successfully delivered lessons in STEM, social studies, and language arts, leveraging interactive activities and multimedia tools to promote critical thinking, collaboration, and creativity among students.• Facilitated a positive and inclusive learning environment that fostered students' academic and social-emotional growth, utilizing research-backed strategies such as positive reinforcement, active listening, and restorative justice. Maintained effective communication with school administrators, teachers, and parents, providing timely feedback and addressing any concerns with empathy and professionalism.• Contributed to the development and implementation of school-wide initiatives by collaborating with colleagues and school administrators, showcasing a strong ability to communicate and work effectively in a team-based environment while upholding high professional standards.

New York, New York

• Expertly managed patient intake, triage, and flow by coordinating appointments, verifying insurance coverage, and conducting pre-procedural assessments to ensure patient safety and optimize procedure outcomes. Skillfully assisted with endoscopic procedures, including scope insertion, tissue sampling, and lesion removal, while closely monitoring vital signs and patient responses.• Demonstrated mastery of clinical documentation by accurately recording detailed patient histories, including relevant symptoms, past medical history, and medication regimens, while effectively communicating findings to the physician. Expertly used the EHR system to document key patient information, process orders, and generate reports that informed diagnosis and treatment decisions.• Effectively supported the physician during complex diagnostic and therapeutic procedures, including colonoscopies, EGDs, and ERCPs, by skillfully managing procedural equipment, monitoring patient vitals, and providing prompt patient care as needed. Actively contributed to patient education by offering detailed instructions on bowel preparation, post-procedure care, and follow-up appointments to ensure optimal patient outcomes.

Department Of Neurological Surgery

• Collaborated closely with a renowned neurosurgeon in complex intracranial and spinal surgeries, constantly seeking to expand knowledge and hone surgical skills. Employed advanced techniques such as endoscopic endonasal surgery, image-guided surgery, and microsurgery to provide the best possible outcomes for patients. Frequently sought out opportunities to learn and grow by attending educational conferences and seminars on the latest advancements in neurosurgery.• Conducted detailed and thorough pre-operative evaluations of patients, striving to understand every aspect of their medical histories and conditions. Played a crucial role in post-operative care, overseeing patient recovery and working tirelessly to manage pain and discomfort, all while keeping a compassionate bedside manner. Exhibited a strong desire to learn by seeking mentorship from experienced practitioners and observing best practices in the field.• Worked in close collaboration with a multidisciplinary team of medical professionals, demonstrating a deep passion for providing the highest level of patient care. Participated in weekly conferences to discuss patient cases and treatment plans with neurosurgeons and medical experts, contributing innovative ideas and insights that helped improve patient outcomes. Showed a relentless drive to learn and grow by continuously seeking out new research studies and publications related to neurosurgery.

Buettner Laboratory For Metabolism And Diabetes

• Investigate the the complex interplay between central nervous system signaling and metabolic regulation through meticulous protein analysis using Western blot and ELISA techniques for key metabolic markers such as PGF, TA, Soleus, and Hypothalamus in rodents.• Conducted a range of metabolic assays to investigate the effects of cold exposure and glucose challenges on metabolic function, including the cold tolerance test (CTT) and glucose tolerance test (GTT), contributing significantly to ongoing studies aimed at understanding the mechanisms underlying metabolic dysregulation in conditions such as obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD).• Leveraged expertise in key metabolic pathways, including de novo lipogenesis, glycogenesis, lipolysis, and uncoupling protein 1 (UCP1), to generate novel insights into the molecular and cellular mechanisms underlying metabolic disorders, contributing to the development of potential therapeutic targets and novel treatment strategies for metabolic diseases.

• Distinguished performance as a seasoned Coordinator, skillfully managing and overseeing the operations of multiple polling sites across various assembly and election districts during each election cycle, ensuring flawless execution of all voting procedures and processes.• Exceptional leadership and mentorship abilities demonstrated in training and managing a diverse team of poll workers, consistently achieving high levels of efficiency, accuracy, and voter satisfaction.• Demonstrated expertise in election law, regulations, and policies, coupled with exceptional problem-solving and critical-thinking abilities, enabling swift resolution of complex logistical and technical issues to ensure an equitable and transparent election process.

• Created unforgettable visual experiences for a diverse range of clients, capturing candid moments and crafting stunning compositions that resonate long after the shoot is over. My photographs are available for purchase as prints or digital copies, providing clients with lasting memories of their special occasions.• Commanded the latest digital technology and professional-grade equipment, including the Sony a7r camera, to produce technically precise and artistically evocative photographs. My images have been featured in prominent publications and are available for purchase as prints or digital copies.• Employed a meticulous attention to detail and a keen artistic vision to produce compelling images for clients in a variety of settings. Leveraged advanced editing techniques in Adobe Creative Suite (including Lightroom and Photoshop) to skillfully enhance color, tone, and composition, creating images that are both visually compelling and emotionally impactful.

• Expertly instruct and guide middle school, high school, and college students in a wide range of subjects, including but not limited to Mathematics, Sciences, Standardized Testing, and Essay Writing, with a proven track record of boosting students' academic performance by up to 40%.• Provide comprehensive college admissions counseling and mentoring services to high school students, offering personalized guidance on selecting colleges, crafting compelling application essays, and preparing for interviews, resulting in an acceptance rate of over 95% for clients in top-tier colleges and universities.• Serve as a trusted consultant and advisor to parents and students, leveraging over nine years of experience and in-depth knowledge of the education landscape to deliver tailored recommendations on educational programs, career paths, and academic enrichment opportunities, resulting in a 100% satisfaction rate among clients.

New York City Metropolitan Area

• Conducted rigorous market research and analysis for leading life sciences companies, utilizing advanced analytics tools such as SAS, PowerBI, and Microsoft Office to deliver critical insights and support strategic decision-making.• Collaborated closely with cross-functional teams to develop and execute comprehensive commercial strategies that drove significant revenue growth and market share gains, achieving an increase in sales and increase in market share across multiple clients.• Led successful sales force optimization initiatives by applying proven methodologies such as data-driven territory optimization, performance analytics, and coaching programs, resulting in improvement in productivity and reduction in operating costs.

Bronx, New York

• Managed patient intake and front desk operations, using electronic medical records (EMR) software to accurately document patient information and ensure smooth operations.• Demonstrated proficiency in communicating with patients and staff, using effective communication skills to manage patient concerns, explain procedures, and facilitate a positive patient experience.• Assisted radiology technicians with positioning patients for imaging exams, using proper protocols to ensure patient safety and accurate exam results.

New York City Metropolitan Area

• Participated in immersive and hands-on medical experiences that included observing cadaver dissection and advanced surgical techniques in the Gross Anatomy Lab, fostering a deep understanding of human anatomy and physiology that laid a strong foundation for future medical studies.• Worked collaboratively with healthcare professionals and fellow students to solve complex medical case studies, such as Diabetes Ketoacidosis and Polycystic Kidney Disease, using critical thinking, analytical skills, and evidence-based medicine to develop comprehensive patient-centered care plans.• Developed practical skills in patient care and surgical procedures by learning how to properly handle operating room appliances and conducting patient checkups under the guidance of experienced physicians. Additionally, gained valuable insight into the healthcare system and the importance of patient-centered care through participation in various community service initiatives and outreach programs.

Department Of Pathology

• Prepared and analyzed diverse tissue samples, including frozen sections and necrotic tissues, using a range of advanced histological techniques such as Hematoxylin and Eosin (H&E) staining, immunohistochemistry, and special staining. Ensured timely delivery of samples and accurate identification of patient specimens, resulting in improved patient care and disease diagnosis.• Analyzed and interpreted pathological specimens, including necrotic tissues and fine needle aspiration biopsies, utilizing advanced microscopy techniques and clinical knowledge to accurately diagnose diseases and guide patient care.• Assisted pathologists in the diagnosis and treatment of patients, including providing critical information on the nature, stage, and progression of various disease conditions. Conducted quality control checks on laboratory equipment, maintained lab inventory, and helped maintain a safe and efficient laboratory environment.

Long Island, Ny

• Utilized pulsed gel electrophoresis to isolate and analyze DNA fragments from environmental samples, resulting in the identification of novel microbial communities and potential indicators of water quality.• Conducted rigorous field sampling and laboratory experiments to study the life histories, growth rates, and ecological roles of multiple species of aquatic organisms, leading to new discoveries about the dynamics of food webs in freshwater ecosystems.• Formulated and tested hypotheses about the relationships between environmental stressors, such as temperature and nutrient availability, and the phenotypic traits of aquatic organisms, advancing our understanding of the ecological and evolutionary consequences of environmental change.

Bachelor'S Degree, Biochemistry, Mathematics Concentration, Gpa: 3.92

Teaching Assistant (General Chemistry Laboratory, Calculus IV, Discrete Time Models in Finance) Undergraduate Peer Tutor Hindu Student.

Bachelor'S Degree, Biological Sciences, Gpa: 4.0

Alpha Epsilon Delta Health Professional Honors Society Society of Scientists and Engineers Emerging Leaders Minority Association.

Valedictorian, Gpa: 105.35

Interact Club (President) Math Team (Captain) Science Olympiad Varsity Track and Field Team (Captain) Varsity Cross Country Team Varsity.