Mohammad Aminul Islam, Ph.D. Email and Phone Number
As a Postdoctoral Associate at the University at Buffalo, I apply my expertise in multiscale modeling and quantitative systems pharmacology to understand and predict the disease dynamics and treatment effects of various inflammatory and fibrotic conditions. I have a Ph.D. in Chemical Engineering from Missouri University of Science and Technology, where I investigated intracellular to tissue-scale phenomena of drug-delivery nanoparticles and bacterial cell populations. I have also trained in human and bacterial cell culture and microfluidic devices in experimental labs.My current research projects include developing a multiscale agent-based simulator to identify the mechanisms of lung fibrosis in COVID-19 patients, building a mathematical model to quantify the patient-specific differences in the renin-angiotensin system and fibrosis outcomes, and integrating pharmacokinetics/pharmacodynamics modeling of bacterial metabolite in the gut-bone axis on osteoimmunology. I have published several papers in peer-reviewed journals and participated in several Kaggle competitions, winning silver and bronze medals. I am always eager to learn new skills and techniques, collaborate with other researchers and experts, and contribute to the advancement of science and medicine. I enjoy solving challenging problems, exploring new ideas, and communicating my findings to diverse audiences. I am looking for opportunities to further develop my career and apply my skills and knowledge to real-world problems and solutions.Google Scholar: https://scholar.google.com/citations?user=MHLemwoAAAAJ&hl=enGitHub: https://github.com/mixvcKaggle: https://www.kaggle.com/aminul01
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Assistant ProfessorUniversity Of DelawareNewark, De, Us -
Postdoctoral AssociateUniversity At Buffalo Jan 2021 - PresentUnited StatesProject A: Developed a multiscale agent-based modeling (ABM) simulator to identify the mechanisms of SARS-CoV-2-mediated fibrosis in the lung tissue of COVID-19 patients. Project B: Built a mathematical model to investigate and quantify patient-specific premorbidity, age, and sex differences on renin-angiotensin system (RAS) in virtual patient cohorts. The ABM tissue simulator was integrated into a model for RAS and fibrosis to account for patient heterogeneity in the systemic alterations in RAS and contribution to lung fibrosis outcomes. -
Postdoctoral ResearcherOklahoma State University Dec 2019 - Dec 2020United StatesIntegrated multicompartment pharmacokinetics (PK)-pharmacodynamics (PD) and mechanistic modeling approaches to quantify the effect of butyrate treatment on regulatory T cells (Tregs) in the gut, blood, and bone (gut-bone axis) and estimate the direct and indirect immune-mediated impacts of butyrate on bone metabolism. -
Graduate Teaching AssistantMissouri University Of Science And Technology Jan 2019 - May 2019Rolla, MoCHE 2100: Materials and Energy Balances -
Graduate Research AssistantMissouri University Of Science And Technology Jan 2015 - May 2019Rolla, MoComputational modeling projectsProject A: Developed a multiscale ABM model by connecting the spatio-temporal features of drug-delivery nanoparticles in the tissue to study the particle size effect on tissue penetration efficacy.Project B: Formulated a multiscale ABM framework using message passing interface (MPI) parallelism to connect the stochastic features of intracellular signaling and gene transcriptions to population dynamics and application to a full-scale model of bacterial quorum sensing.Project C: Developed a dynamic ABM modeling framework to simulate the structure-based interactions of ligand-receptor and enzyme-substrate to investigate the binding kinetics and complex formation.Experimental projectsProject A: Designed experiments to collect time-series microscopic images of bacterial cell motility and formulated mathematical models to analyze their size and concentration-dependent anomalous diffusion behavior. Image J was used to quantify the time-dependent displacement of cells from microscopic images.Project B: Conducted experiments to identify the response of different strains of E. coli in various antibiotics, temperatures, and initial concentrations. The cell population's response was quantified using flow cytometry, microplate reader, and solid agar plating.
Mohammad Aminul Islam, Ph.D. Education Details
Frequently Asked Questions about Mohammad Aminul Islam, Ph.D.
What company does Mohammad Aminul Islam, Ph.D. work for?
Mohammad Aminul Islam, Ph.D. works for University Of Delaware
What is Mohammad Aminul Islam, Ph.D.'s role at the current company?
Mohammad Aminul Islam, Ph.D.'s current role is Assistant Professor.
What schools did Mohammad Aminul Islam, Ph.D. attend?
Mohammad Aminul Islam, Ph.D. attended Missouri University Of Science And Technology, Bangladesh University Of Engineering And Technology.
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