Amirmahdi Mostofinejad
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Amirmahdi Mostofinejad Email & Phone Number

Applied Scientist at Amazon
Location: Virginia, United States, United States 7 work roles 3 schools
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Current company
Role
Applied Scientist
Location
Virginia, United States, United States
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Who is Amirmahdi Mostofinejad? Overview

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Amirmahdi Mostofinejad is listed as Applied Scientist at Amazon, a company with 7553 employees, based in Virginia, United States, United States. AeroLeads shows a matched LinkedIn profile for Amirmahdi Mostofinejad.

Amirmahdi Mostofinejad previously worked as Research Assistant at University Health Network and Research Assistant at University Of Toronto. Amirmahdi Mostofinejad holds Doctor Of Philosophy - Phd, Mechanical Engineering from University Of Toronto.

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Profile bio

About Amirmahdi Mostofinejad

I am a Ph.D. candidate at the University of Toronto. My background is in mathematical abstraction, formulation, and model inference for biological processes, with my master’s on tumor-induced angiogenesis and my Ph.D. on population dynamics of induced pluripotent stem cells (iPSCs), focusing on their differentiation towards lung progenitors. This includes performing model selection between multiple biologically informed models using sparse experimental data. I also spent a Summer at Genentech working on translational QSP modeling of drug effects on non-small lung cancer cells. There, I developed and validated a pharmacokinetics-pharmacodynamics model for two small molecule drugs undergoing FDA approval, leveraging predictive modeling and simulation tools to optimize drug efficacy and safety. I have extensively utilized Python, Julia, and MATLAB throughout my projects for model preprocessing, numerical solvers, optimization, and visualization, demonstrating a strong ability to adapt quickly and learn new tools. I am interested in improving human health using multidisciplinary methods incorporating concepts from dynamical systems, solid and fluid mechanics, biochemistry, and biology. A non-exhaustive list of my skills gained from my studies are as follows,Concepts: Solid mechanics, fluid dynamics, multiphysical systems, dynamical systems, nonlinear modeling, optimization, model identification, physics-informed machine learning, deep learningProgramming: Julia, Python, MATLAB, C/C++Software packages: SciML, Flux, SciPy, PyTorch, Tensorflow, scikit-learnCommercial solvers: COMSOL Multiphysics, FEniCS, Ansys, Abaqus FEAMisc.: ParaView, Solidworks, Netfabb, AutoCAD, gmsh, Git, Linux, LaTeX

Listed skills include Biomechanics, Matlab, Finite Element Analysis, Civil Engineering, and 35 others.

Current workplace

Amirmahdi Mostofinejad's current company

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Amazon
Amazon
Applied Scientist
New York, NY, US
Website
Employees
7553
AeroLeads page
7 roles

Amirmahdi Mostofinejad work experience

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Applied Scientist

New York, NY, US

Research Assistant

Current

Toronto, Canada Area

  • Highlights of research:
  • Designed and ran cell growth experiments in different biochemical and mechanical environments.
Sep 2019 - Present

Research Assistant

Current
  • Highlights of research:
  • Developed three mathematical models for BEAS-2Bs, induced pluripotent stem cells (iPSCs), and anterior foregut endoderm population dynamics using global optimization and parameter identifiability supervised by Prof..
  • Developed a methodology for inferring unique biologically-informed mathematical models and applying it to in vitro cell population dynamics.
  • Optimized state-of-the-art experimental protocols for cell culture using the developed models.Instructed tutorials, supervised and assisted in laboratory experiments, graded exams, reports, and projects, and held.
  • Numerical Methods I (MIE334)
  • Data Science Methods and Quantitative Analysis (MIE1625)
May 2019 - Present

Quantitative/Computational Systems Pharmacology

South San Francisco, California, United States

  • Highlights of research:
  • Translational quantitative systems pharmacology (QSP) modeling of drug effects on KRAS-G12C alkylation and MAPK pathway inhibition for supporting clinical development.
  • Developed a QSP model for the effect of two non-small cell lung cancer drugs on MAPK cascade and their effect on tumor growth in humans and mice using MathWorks SimBiology and Julia, supervised by Dan Lu.
  • Performed statistical analysis on longitudinal data to inform candidate models.
  • Developed a toolbox to facilitate data flow between different phases of model development previously done manually. This toolbox performed clinical data cleaning, made publication-ready visualizations and tables, and.
Jun 2023 - Sep 2023

Research And Teaching Assistant

Waterloo, Ontario, Canada

  • Highlights of research:
  • Modeled tumor-induced angiogenesis by modeling the migration of the endothelial cells and their interaction with the extracellular matrix, supervised by Prof. Adil Al-Mayah.
  • Solved a system of partial differential equations describing the biochemical, mechanical, and vasculature using nonlinear finite element analysis in MATLAB.Instructed tutorials, supervised and assisted in laboratory.
  • Mechanics of Solids II (CivE 205)
  • Structural Concrete Design I (CivE 313)
  • Physics I - Statics (BME 181)
Sep 2016 - May 2019

Undergraduate Teaching Assistant

Tehran, Tehran Province, Iran

Lab teaching assistant for the course “Concrete Technology and Lab”

Sep 2014 - Jan 2015

Intern

Prestige Land Iran Co

Isfahan

  • A part of the supervision system in the Isfahan City Center construction project, the largest shopping mall in Iran
  • Sampled and tested the quality of concrete specimens
  • Checked the final stage of construction
  • Checked the design calculations and drawings
May 2014 - Aug 2014
Team & coworkers

Colleagues at Amazon

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3 education records

Amirmahdi Mostofinejad education

Master Of Science (Msc), Civil Engineering

Activities and Societies: Iranian Students' Association of Waterloo

FAQ

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What company does Amirmahdi Mostofinejad work for?

Amirmahdi Mostofinejad works for Amazon.

What is Amirmahdi Mostofinejad's role at Amazon?

Amirmahdi Mostofinejad is listed as Applied Scientist at Amazon.

Where is Amirmahdi Mostofinejad based?

Amirmahdi Mostofinejad is based in Virginia, United States, United States while working with Amazon.

What companies has Amirmahdi Mostofinejad worked for?

Amirmahdi Mostofinejad has worked for Amazon, University Health Network, University Of Toronto, Genentech, and University Of Waterloo.

Who are Amirmahdi Mostofinejad's colleagues at Amazon?

Amirmahdi Mostofinejad's colleagues at Amazon include Tomasz Grabiec, Olga Kudritska, Jiaxuan Wan, Shahithra Ramesh, and Annie Yu.

How can I contact Amirmahdi Mostofinejad?

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What schools did Amirmahdi Mostofinejad attend?

Amirmahdi Mostofinejad holds Doctor Of Philosophy - Phd, Mechanical Engineering from University Of Toronto.

What skills is Amirmahdi Mostofinejad known for?

Amirmahdi Mostofinejad is listed with skills including Biomechanics, Matlab, Finite Element Analysis, Civil Engineering, Microsoft Excel, Microsoft Office, Biotechnology, and Microsoft Word.

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