Amirtha Priya Ramesh Email & Phone Number

London Area, United Kingdom

Supervisor-Dominique Bonnet -Haematopoietic Stem Cell Laboratory- Working on a project to improve early detection of blood cancer by studying the correlation between mutation frequency and low-granule neutrophils.

United Kingdom

Research Assistant in the group of Professor George Vassiliou within the Department of Haematology and the Wellcome-MRC Cambridge Stem Cell Institute on the Cambridge Biomedical Campus.Working on an exciting project to study the pathogenesis and treatment of clonal haematopoiesis and related blood malignancies, with the aim of identifying new preventive and therapeutic approaches for these diseases.

Manchester Area, United Kingdom

• Facilitated simulation-based medical skills training, including role play and communication, for diverse healthcare professionals and PLAB exam learners.• Evaluated diagnosis, communication, and management skills of 70-85 students to ensure medical professionalism and patient safety.• Demonstrated effective communication and interpersonal skills while interacting with healthcare professionals and learners from diverse backgrounds.

United Kingdom

• Learnt modules on immune responses, immune-oncology and diagnostic mechanisms and studied new therapeutical approaches. • Presented clinical case studies to public and developed good communication skills and exposure to strategically answer questions from scientific experts. • Deciphered new publications and prepared reports, scientific news articles and patient leaflets to apply our knowledge from the Immunodeficiency and Immunotherapy, Hypersensitivity and Allergy, Autoimmunity and Hematological Malignancy modules.Clinical Laboratory Experience:• Gained hands on practical experience on ELISA which monitored HBV vaccine responses, and subsequent patient response to therapeutic biologic therapies such as infliximab.• Analyzed the components of patient blood via serum protein electrophoresis as a method of clinical investigation for: multiple myeloma, hyper IgM syndrome or hypogammaglobulinemia as a sign of immune deficiency,• Performed flow cytometry to identify cell types via surface antigens in an immune cell population.

United Kingdom

Research project on The influence of the circadian clock on intestinal epithelial cell function , under the supervision of Dr. Julie Gibbs, Professor, University of Manchester, AV Hill, Faculty of Biology, Medicine and Health. The project used a transgenic mouse line lacking the core clock gene Rev-erb alpha in IECs (Villin-Rev-erb alpha -/-) and assessing the consequence of this manipulation on intestinal epithelial cell function, and effects of disease progression and inflammation. Analytical Techniques of interest include QPCR, ELISA and histology to assess gene expression, barrier permeability and barrier integrity and flow cytometry and QPCR to access disease progression and severity in response to induced inflammation.Achievements: Completed the project, anlaysed the data with required statistics and defended a 15,000 word thesis accumulating an overall 71% final grade on the masters thesis.

Manchester, England, United Kingdom

India

Worked at the Molecular Immunology Laboratory under the supervision of Dr. E. Berla Thangam (Former Professor, SRMIST, India)Research Topic: Checking molecular characteristics of food proteins like millets and their immunomodulatory effects on human mast cells (HMC-1) The techniques employed in the project include protein extraction(digestive hydrolysis by pepsin/trypsin) protein/peptide isolation(membrane ultrafiltration) and protein quantification (Bradford's protein quantification and SDS-PAGE electrophoresis).The immune modulation of the purified protein was checked using ELISA and Western Blotting which quantified pro and anti-inflammatory cytokine production and inflammatory signal phosphorylation.Key Roles: 1)Studied and specialized in Molecular Immunology techniques, protein-peptide characterization, and internal mast cell interaction (H4 Receptors)during inflammation.2)Planned, coordinated, and successfully completed a research project and achieved a 93%(A+) grade average on a 20,000 words dissertation and panel presentation.

Tamil Nadu, India

Worked at the Integrative Medicine Laboratory under the supervision of Dr.S.Thyagarajan (Former HOD, Dept. of Biotechnology, SRMIST, India)Gained subject knowledge and research input on Integrative Medicine and Neuro-Endocrine-Immune interaction in aging.Key Role:Supported advanced field research by assisting with experimental design, execution, and results tracking.Conducted research for writing review papers, project proposals, poster presentations, and workshops.

Chennai, Tamil Nadu, India

Attended a summer internship at the Council Of Scientific And Industrial Research–Central Leather Research Institute at Centre forAnalysis, Testing, Evaluation, and Reporting ServicesKey roles:1)Assisted in chemical and leather sample analysis, data compilation, and generation of timely reports on products requiring quality checks using instruments like HPLC, LCMS-MS, and MALDI-TOFF.2)Maximized productivity by analyzing protocols and identifying areas for improvement.3)Presented the skills obtained from the summer internship for the university industrialplacement module and received an 89% overall grade.

Master Of Science - Msc, Clinical Immunology, Overall Merit, With A 70 % On The Final Masters Project And Thesis

Acquired professional experience in advanced clinical immunology and a comprehensive understanding of autoimmune and inflammatory.

Bachelor Of Technology - Btech, Biotechnology, 80.15

Received a First Class with a Distinction degree with an overall percentage of 80.15 % Completed professional education in various.

Education record